FTO 抗体
(Fat Mass and Obesity-Associated (FTO))
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| FTO 抗体 | 人 | 兔 Monoclonal |
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| Recombinant FTO 抗体 | 人 | 兔 Monoclonal |
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| FTO 抗体 (AA 279-505) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| FTO 抗体 | 人 | 小鼠 Monoclonal |
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| FTO 抗体 | 小鼠 | 小鼠 Monoclonal |
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| Recombinant FTO 抗体 | 人 | 兔 Monoclonal |
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| Recombinant FTO 抗体 | 人 | 兔 Monoclonal |
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| Recombinant FTO 抗体 | 人 | 兔 Monoclonal |
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| FTO 抗体 | 人 | 小鼠 Monoclonal |
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| FTO 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| FTO 抗体 (N-Term) | 大鼠 | 小鼠 Monoclonal |
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| FTO 抗体 (N-Term) | 人, 小鼠, 大鼠, Cow, 绵羊, Pig, 马, 猴, Hamster | 兔 Polyclonal |
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| FTO 抗体 (AA 416-505) | 人 | 兔 Polyclonal |
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| FTO 抗体 | 小鼠 | 兔 Polyclonal |
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| FTO 抗体 | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| FTO 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| FTO 抗体 | 人, 小鼠, 大鼠, 犬, Cow, 绵羊, 马, 灵长类 | 小鼠 Monoclonal |
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| FTO 抗体 (AA 165-265) | 人 | 兔 Polyclonal |
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| FTO 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| FTO 抗体 | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 4G9
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 279-505
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
KO 验证
- 质量等级
- KO Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 25GB3630
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
KO 验证
- 质量等级
- KO Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 25GB3625
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
KO 验证
- 质量等级
- KO Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 25GB2700
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB21572
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 1-30, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
6 references - 适用
- 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5-2H10
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- N-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠, Cow, 绵羊, Pig, 马, 猴, Hamster
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 416-505
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠, 犬, Cow, 绵羊, 马, 灵长类
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5-2H10
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 165-265
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Latest Publications for our FTO 抗体
: "m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2." in: Nature communications, Vol. 10, Issue 1, pp. 5332, (2020) (PubMed).
: "Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates." in: Nature chemical biology, Vol. 15, Issue 9, pp. 865-871, (2019) (PubMed).
: "N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response." in: Molecular cell, Vol. 69, Issue 4, pp. 636-647.e7, (2019) (PubMed).
: "N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications." in: Nature neuroscience, Vol. 21, Issue 2, pp. 195-206, (2019) (PubMed).
: "Dynamic m6A modification regulates local translation of mRNA in axons." in: Nucleic acids research, Vol. 46, Issue 3, pp. 1412-1423, (2019) (PubMed).
: "The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 42, Issue 7, pp. 1502-1510, (2017) (PubMed).
: "FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1-induced transcription." in: Biochemical and biophysical research communications, Vol. 464, Issue 3, pp. 826-32, (2015) (PubMed).
: "Dynamic m(6)A mRNA methylation directs translational control of heat shock response." in: Nature, Vol. 526, Issue 7574, pp. 591-4, (2015) (PubMed).
: "The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. ..." in: Science (New York, N.Y.), Vol. 318, Issue 5855, pp. 1469-72, (2007) (PubMed).
: "Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates." in: Nature chemical biology, Vol. 15, Issue 9, pp. 865-871, (2019) (PubMed).
: "N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response." in: Molecular cell, Vol. 69, Issue 4, pp. 636-647.e7, (2019) (PubMed).
: "N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications." in: Nature neuroscience, Vol. 21, Issue 2, pp. 195-206, (2019) (PubMed).
: "Dynamic m6A modification regulates local translation of mRNA in axons." in: Nucleic acids research, Vol. 46, Issue 3, pp. 1412-1423, (2019) (PubMed).
: "The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 42, Issue 7, pp. 1502-1510, (2017) (PubMed).
: "FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1-induced transcription." in: Biochemical and biophysical research communications, Vol. 464, Issue 3, pp. 826-32, (2015) (PubMed).
: "Dynamic m(6)A mRNA methylation directs translational control of heat shock response." in: Nature, Vol. 526, Issue 7574, pp. 591-4, (2015) (PubMed).
: "The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. ..." in: Science (New York, N.Y.), Vol. 318, Issue 5855, pp. 1469-72, (2007) (PubMed).
Aliases for FTO 抗体
FTO, alpha-ketoglutarate dependent dioxygenase (FTO) 抗体fat mass and obesity associated (Fto) 抗体
FTO, alpha-ketoglutarate dependent dioxygenase (Fto) 抗体
fat mass and obesity associated L homeolog (fto.L) 抗体
AW743446 抗体
mKIAA1752 抗体
RGD1305121 抗体
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