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FTO 抗体 (N-Term)

FTO 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6971672
发货至: 中国
  • 抗原 See all FTO 抗体
    FTO (Fat Mass and Obesity-Associated (FTO))
    抗原表位
    • 17
    • 15
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 61
    • 28
    • 25
    • 6
    • 6
    • 6
    • 6
    • 3
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    • 1
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    • 1
    宿主
    • 53
    • 8
    • 1
    • 1
    克隆类型
    • 44
    • 19
    多克隆
    标记
    • 34
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    This FTO antibody is un-conjugated
    应用范围
    • 56
    • 23
    • 18
    • 14
    • 14
    • 13
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    产品特性
    FTO (fat mass and obesity associated) is a dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. This protein has high activity towards single-stranded RNA containing 3-methyluracil and single-stranded DNA containing 3-methylthymine. FTO has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine and has no activity towards 1-methylguanine or double-stranded DNA. FTO contributes to the regulation of the global metabolic rate, energy expenditure, energy homeostasis, regulation of body size and body fat accumulation. FTO has recently been shown to have the highest activity towards demethylation of 6-methyladeninine in single-stranded RNA suggesting that FTO is involved in processing of nuclear RNAs and may play an important role in RNA epigenetics. FTO antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
    纯化方法
    Affinity Purified
    免疫原
    This antibody was raised against a peptide within the N-terminal region of human FTO.
    亚型
    IgG
    Top Product
    Discover our top product FTO Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原
    FTO (Fat Mass and Obesity-Associated (FTO))
    别名
    FTO (FTO 产品)
    别名
    AW743446 antibody, mKIAA1752 antibody, RGD1305121 antibody, FTO, alpha-ketoglutarate dependent dioxygenase antibody, fat mass and obesity associated antibody, fat mass and obesity associated L homeolog antibody, FTO antibody, Fto antibody, fto.L antibody
    分子量
    60 kDa
    NCBI登录号
    NP_001073901
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