May play a role in apoptosis suppression (By similarity).. 再加上，我们可以发FAM129B 蛋白 (5) 和 和数多这个蛋白质的别的产品。
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Human Polyclonal FAM129B Primary Antibody for ICC, IF - ABIN4310187
Conrad, Major, Cleary, Ferrer, Roberts, Marine, Chung, Arthur, Moon, Berndt, Chien: FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells. in F1000Research 2014
We have demonstrated that FAM129B in cancer promotes Nrf2 activity by reducing its ubiquitination through competition with Nrf2 for Keap1 binding via its DLG and ETGE motifs. In addition, FAM129B reduces chemosensitivity by augmenting Nrf2 antioxidative signaling and confers poor prognosis in breast and lung cancer
activated EGFR phosphorylates the Y593 residue of the protein known as family with sequence similarity 129, member B (FAM129B), which is overexpressed in many types of human cancer.
The rapid induction of apoptosis in FAM129B knockdown cells was reversed by co-transfection with recombinant FAM129B, indicating that its effect on apoptosis was specific.
Phosphorylation of FAM129B has a role in controlling melanoma cell invasion.
Fam129b in epidermal keratinocytes accompanied by alteration of wound healing-related gene expression is necessary for regulation of cell motility.
May play a role in apoptosis suppression (By similarity).
melanoma invasion by ERK
, niban-like protein 1
, family with sequence similarity 129, member B
, hypothetical protein LOC100145245
, Niban-like protein 1