anti-E74-Like Factor 5 (Ets Domain Transcription Factor) (ELF5) 抗体

The protein encoded by ELF5 is a member of an epithelium-specific subclass of the Ets transcritpion factor family. 再加上,我们可以发ELF5 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ELF5 13711 Q8VDK3
ELF5 366142  
ELF5 2001 Q9UKW6
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antibodies-online.cn销售最多的anti-ELF5 抗体

Showing 10 out of 72 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-Elf5 Antibody Titration: 0.2-1 ug/ml Positive Control: Mouse Kidney 100 μL Log in to see 2至3个工作日
山羊 非结合性 ELISA   100 μg Log in to see 6至7个工作日
Cow 非结合性 IC, IF, IP, WB Immunofluorescent analysis of ELF5 staining in HuvEc cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of ELF5 expression in HeLa (A), HuvEc (B), Jurkat (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
非结合性 ELISA, WB Western blot analysis of extracts from Jurkat/293/HuvEc cells, using ELF5 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
非结合性 EIA, WB 0.4 mL Log in to see 6至8个工作日
Bat 非结合性 IHC, IHC (p), WB Mouse Salivary Glands: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-ELF5 antibody IHC of mouse salivary glands. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. O ... 50 μg Log in to see 11至14个工作日
非结合性 WB Western blot analysis of ELF5 Antibody (Center) (ABIN391589) in MCF7,T47D cell line lysates and mouse lung tissues lysates(35 µg/lane). ELF5 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of ELF5 (arrow) using rabbit polyclonal ELF5 Antibody (Center) (ABIN391589). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ELF5 gene. 400 μL Log in to see 10至11个工作日
山羊 非结合性 IHC (p), IHC, ELISA Immunohistochemistry-Paraffin: ELF5 Antibody [ABIN249582] - (4ug/ml) staining of paraffin embedded Human Thyroid Gland. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. 0.1 mg Log in to see 7至9个工作日
非结合性 ELISA, IF, WB 100 μL Log in to see 16 Days
非结合性 ELISA, ICC, IF, WB Western blot analysis of ELF5 using Jurkat whole cell lysates ABIN6278568 staining LOVO by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL Log in to see 11至12个工作日

引用最多的anti-ELF5 抗体

  1. Human Polyclonal ELF5 Primary Antibody for IHC (p), IHC - ABIN249582 : Oettgen, Kas, Dube, Gu, Grall, Thamrongsak, Akbarali, Finger, Boltax, Endress, Munger, Kunsch, Libermann: Characterization of ESE-2, a novel ESE-1-related Ets transcription factor that is restricted to glandular epithelium and differentiated keratinocytes. in The Journal of biological chemistry 1999 (PubMed)


Mouse (Murine) E74-Like Factor 5 (Ets Domain Transcription Factor) (ELF5) interaction partners

  1. Downregulation of ELF5 increases the expression of AR-response genes and the progression of prostate cancer. ELF5 interaction with AR is androgen dependent.

  2. Conditional inactivation of Elf5 in the developing collecting ducts results in a small but significant reduction in the expression levels of Aqp2 (显示 AQP2 抗体) and Avpr2 (显示 AVPR2 抗体) genes.

  3. Mechanistically, RL negatively regulates Stat5 (显示 STAT5A 抗体) phosphorylation and Elf5 expression at the onset of lactogenesis. Continuous RL exposure leads to the expansion of basal and bipotent cells in WT and MMTV-RANK acini. Overall, we demonstrate that enhanced Rank signaling impairs secretory differentiation during pregnancy by inhibition of the prolactin (显示 PRL 抗体)/p-Stat5 (显示 STAT5A 抗体) pathway.

  4. Elf5 at the center of a stoichiometry-sensitive transcriptional network, where it acts as a molecular switch governing the balance between TSC (显示 SLC12A3 抗体) proliferation and differentiation

  5. Elf5 and Ets2 (显示 ETS2 抗体) maintain the mouse extraembryonic ectoderm in a dosage dependent synergistic manner

  6. Elf5 counteracts precocious trophoblast differentiation by maintaining Sox2 (显示 SOX2 抗体) and 3 and inhibiting Hand1 (显示 HAND1 抗体) expression.

  7. Blockade of RankL (显示 TNFSF11 抗体) action prevented progesterone-induced side branching and the expansion of Elf5(+) mature luminal cells.

  8. Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2.

  9. Studies suggest that Elf5 loss leads to hyperactivation of the Notch (显示 NOTCH1 抗体) signaling pathway, which might constitute in part, the underlying molecular mechanism for the altered cell lineage decisions in Elf5-null mammary epithelial cells.

  10. Elf5 promoter methylation is regulated during mammary differentiation in vivo.

Human E74-Like Factor 5 (Ets Domain Transcription Factor) (ELF5) interaction partners

  1. Elf5 expression was associated with decreased overall and disease-free survival of triple negative breast cancers patients.

  2. When ELF5 was transfected into the parental MCF7 cells that lack CEACAM1 (显示 CEACAM1 抗体), lumen formation was restored, indicating that ELF5 can replace CEACAM1 (显示 CEACAM1 抗体) in this model system of lumenogenesis.

  3. These results support the contention that ABO (显示 ABO 抗体) expression is dependent upon a downstream positive regulatory element functioning through a tissue-restricted transcription factor, Elf5, in epithelial cells.

  4. Low ELF5 expression is associated with ovarian cancer.

  5. The results of this study suggest that ELF5 is a candidate gene that confers genetic susceptibility for pediatric asthma in the Taiwanese population and SNP rs3910901 may have a minor impact on pediatric asthma in the Taiwanese population.

  6. a novel EWSR1 (显示 EWSR1 抗体)/ETS (显示 ETS1 抗体) chimeric gene, was identified in a patient diagnosed with refractory AML (显示 RUNX1 抗体), suggesting a potential role of leukemogenesis in rare cases of AML (显示 RUNX1 抗体). This fusion gene is very likely to exhibit oncogenic potential by interfering with the p53 (显示 TP53 抗体)/p21 (显示 CDKN1A 抗体)-dependent pathway.

  7. Alternative promoter use, conferring differential regulatory responses, is the main mechanism governing ELF5 action rather than differential transcriptional activity of the isoforms.

  8. Data (including data from studies in transgenic mice) suggest that expression of ELF5 in luminal breast cancer correlates with increased myeloid cell invasion, inflammation, and lung metastasis.

  9. we identified Elf5 as a novel biomarker of urothelial cancer on several biological levels and established a causative link between Elf5 and epithelial-mesenchymal transition in urothelial cancer.

  10. Elf5 expression is inversely correlated with epithelial-mesenchymal transition in prostate cancer.

Cow (Bovine) E74-Like Factor 5 (Ets Domain Transcription Factor) (ELF5) interaction partners

  1. Elf5 regulation in the trophectoderm

ELF5 抗原简介


The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with ELF5

  • E74 like ETS transcription factor 5 (ELF5) 抗体
  • E74-like factor 5 (Elf5) 抗体
  • E74 like ETS transcription factor 5 (Elf5) 抗体
  • ESE-2 抗体
  • ESE-5 抗体
  • ESE-5. 抗体
  • ESE2 抗体

Protein level used designations for ELF5

E74-like factor 5 (ets domain transcription factor) , ETS-related transcription factor Elf-5 , Epithelium specific Ets-2 , epithelium-restricted ESE-1-related Ets factor , epithelium-specific Ets transcription factor 2 , E74-like factor 5 ESE-2a

608908 Canis lupus familiaris
739906 Pan troglodytes
13711 Mus musculus
366142 Rattus norvegicus
2001 Homo sapiens
539420 Bos taurus
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