anti-E74-Like Factor 5 (Ets Domain Transcription Factor) (ELF5) 抗体

The protein encoded by ELF5 is a member of an epithelium-specific subclass of the Ets transcritpion factor family. 再加上,我们可以发ELF5 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ELF5 13711 Q8VDK3
ELF5 366142  
ELF5 2001 Q9UKW6
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • 在线下订单

antibodies-online.cn销售最多的anti-ELF5 抗体

Showing 10 out of 76 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-Elf5 Antibody Titration: 0.2-1 ug/ml Positive Control: Mouse Kidney 100 μL 2至3个工作日
山羊 非结合性 ELISA ABIN184782 (4µg/ml) staining of paraffin embedded Human Thyroid Gland. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. This data is from a previous batch, not on sale. 100 μg 6至7个工作日
Cow 非结合性 IC, IF, IP, WB Immunofluorescent analysis of ELF5 staining in HuvEc cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of ELF5 expression in HeLa (A), HuvEc (B), Jurkat (C) whole cell lysates. 200 μL 13至14个工作日
非结合性 ELISA, WB Western blot analysis of extracts from Jurkat/293/HuvEc cells, using ELF5 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2至3个工作日
非结合性 EIA, WB 0.4 mL 6至8个工作日
Bat 非结合性 IHC, IHC (p), WB Mouse Salivary Glands: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-ELF5 antibody IHC of mouse salivary glands. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. O ... 100 μL 11至14个工作日
非结合性 ELISA, IF, WB 100 μL Available
非结合性 ELISA, ICC, IF, WB Western blot analysis of ELF5 using Jurkat whole cell lysates ABIN6278568 staining LOVO by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL 11至12个工作日
Bat 山羊 非结合性 ELISA   100 μg 11至14个工作日
非结合性 IF/ICC, WB Western blot analysis of extracts of various cell lines, using ELF5 antibody (ABIN5974316) at 1/1000 dilution. Immunofluorescence analysis of A549 cells using ELF5 antibody (ABIN5974316). Blue: DAPI for nuclear staining. 100 μL 11至16个工作日

引用最多的anti-ELF5 抗体

  1. Human Polyclonal ELF5 Primary Antibody for IHC (p), IHC - ABIN249582 : Oettgen, Kas, Dube, Gu, Grall, Thamrongsak, Akbarali, Finger, Boltax, Endress, Munger, Kunsch, Libermann: Characterization of ESE-2, a novel ESE-1-related Ets transcription factor that is restricted to glandular epithelium and differentiated keratinocytes. in The Journal of biological chemistry 1999 (PubMed)


Mouse (Murine) E74-Like Factor 5 (Ets Domain Transcription Factor) (ELF5) interaction partners

  1. Downregulation of ELF5 increases the expression of AR-response genes and the progression of prostate cancer. ELF5 interaction with AR is androgen dependent.

  2. Conditional inactivation of Elf5 in the developing collecting ducts results in a small but significant reduction in the expression levels of Aqp2 and Avpr2 genes.

  3. Mechanistically, RL negatively regulates Stat5 phosphorylation and Elf5 expression at the onset of lactogenesis. Continuous RL exposure leads to the expansion of basal and bipotent cells in WT and MMTV-RANK acini. Overall, we demonstrate that enhanced Rank signaling impairs secretory differentiation during pregnancy by inhibition of the prolactin/p-Stat5 pathway.

  4. Elf5 at the center of a stoichiometry-sensitive transcriptional network, where it acts as a molecular switch governing the balance between TSC proliferation and differentiation

  5. Elf5 and Ets2 maintain the mouse extraembryonic ectoderm in a dosage dependent synergistic manner

  6. Elf5 counteracts precocious trophoblast differentiation by maintaining Sox2 and 3 and inhibiting Hand1 expression.

  7. Blockade of RankL action prevented progesterone-induced side branching and the expansion of Elf5(+) mature luminal cells.

  8. Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2.

  9. Studies suggest that Elf5 loss leads to hyperactivation of the Notch signaling pathway, which might constitute in part, the underlying molecular mechanism for the altered cell lineage decisions in Elf5-null mammary epithelial cells.

  10. Elf5 promoter methylation is regulated during mammary differentiation in vivo.

  11. identify novel transcriptional targets of Elf5 and show that Muc4 is a direct target of Elf5, further elucidating the mechanisms through which Elf5 regulates proliferation and differentiation in the mammary gland

  12. Results identify a novel Elf5-binding segment upstream of the Ccnd2 gene and demonstrate that Elf5 can transcriptionally repress Ccnd2 by directly binding to the proximal promoter region.

  13. Elf5 is essential for developmental processes in the embryo and in the mammary gland during pregnancy

  14. demonstrated for the first time that Elf5 protein is localised to epithelium of exocrine glands including the kidney, mammary gland, stomach and the submandibular salivary gland

  15. Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning.

  16. KRF is a novel transcription factor that is restricted to nuclear extracts isolated from keratinocytes and that binds to unique DNA sequences, which do not resemble any known consensus binding motif for transcription factors.[KRF]

  17. Socs2 and Elf5 are key members of the set of prolactin-regulated genes that mediate prolactin-driven mammary development.

  18. Elf5 is an FGF-sensitive transcription factor in the lung with a dynamic pattern of expression, and FGF regulation of Elf5 by means of FGFR2b occurs through the PI3-Kinase/Akt pathway.

  19. analysis reveals previously undiscovered expression site for Elf5 in the differentiated cells of the inner root sheath of hair follicle

  20. Elf5 specifies the differentiation of CD61+ progenitors to establish the secretory alveolar lineage during pregnancy, providing a link between prolactin, transcriptional events, and alveolar development.

Human E74-Like Factor 5 (Ets Domain Transcription Factor) (ELF5) interaction partners

  1. Authors found that expression of ELF5 was obviously decreased in ovarian cancer cell lines. The cells viability, invasion and metastasis were inhibited by overexpression ELF5.

  2. Elf5 expression was associated with decreased overall and disease-free survival of triple negative breast cancers patients.

  3. When ELF5 was transfected into the parental MCF7 cells that lack CEACAM1, lumen formation was restored, indicating that ELF5 can replace CEACAM1 in this model system of lumenogenesis.

  4. These results support the contention that ABO expression is dependent upon a downstream positive regulatory element functioning through a tissue-restricted transcription factor, Elf5, in epithelial cells.

  5. Low ELF5 expression is associated with ovarian cancer.

  6. The results of this study suggest that ELF5 is a candidate gene that confers genetic susceptibility for pediatric asthma in the Taiwanese population and SNP rs3910901 may have a minor impact on pediatric asthma in the Taiwanese population.

  7. a novel EWSR1/ETS chimeric gene, was identified in a patient diagnosed with refractory AML, suggesting a potential role of leukemogenesis in rare cases of AML. This fusion gene is very likely to exhibit oncogenic potential by interfering with the p53/p21-dependent pathway.

  8. Alternative promoter use, conferring differential regulatory responses, is the main mechanism governing ELF5 action rather than differential transcriptional activity of the isoforms.

  9. Data (including data from studies in transgenic mice) suggest that expression of ELF5 in luminal breast cancer correlates with increased myeloid cell invasion, inflammation, and lung metastasis.

  10. we identified Elf5 as a novel biomarker of urothelial cancer on several biological levels and established a causative link between Elf5 and epithelial-mesenchymal transition in urothelial cancer.

  11. Elf5 expression is inversely correlated with epithelial-mesenchymal transition in prostate cancer.

  12. ELF5 provides a key transcriptional determinant of breast cancer molecular subtype by suppression of estrogen sensitivity in luminal breast cancer cells.

  13. Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2.

  14. Loss of ELF5 is associated with kidney cancer.

  15. ELF5 is expressed in the human placenta in villous cytotrophoblast cells but not in post-mitotic syncytiotrophoblast and invasive extravillous cytotrophoblast cells.

  16. findings show that Ese-2 upregulates K18 gene expression through specific interactions within ETS binding sites in the regulatory first intron of the gene

  17. Our studies have identified a critical stretch of nucleotides that is important for both basal as well as calcium responsive reporter activity and that binds to a nuclear factor, keratinocyte restricted factor (KRF).

  18. Identification of the ESE-2 consensus site and characterization of the transcriptional activation properties of ESE-2 shed new light on its potential as a regulator of target genes.

Cow (Bovine) E74-Like Factor 5 (Ets Domain Transcription Factor) (ELF5) interaction partners

  1. Elf5 regulation in the trophectoderm

ELF5 抗原简介


The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with ELF5

  • E74 like ETS transcription factor 5 (ELF5) 抗体
  • E74-like factor 5 (Elf5) 抗体
  • E74 like ETS transcription factor 5 (Elf5) 抗体
  • ESE-2 抗体
  • ESE-5 抗体
  • ESE-5. 抗体
  • ESE2 抗体

Protein level used designations for ELF5

E74-like factor 5 (ets domain transcription factor) , ETS-related transcription factor Elf-5 , Epithelium specific Ets-2 , epithelium-restricted ESE-1-related Ets factor , epithelium-specific Ets transcription factor 2 , E74-like factor 5 ESE-2a

608908 Canis lupus familiaris
739906 Pan troglodytes
13711 Mus musculus
366142 Rattus norvegicus
2001 Homo sapiens
539420 Bos taurus
anti-ELF5 (ELF5) 抗体 精选生产商