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Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995 [PubMed 7738094]). 再加上，我们可以发Dynein, Cytoplasmic 1, Light Intermediate Chain 2 蛋白 (7)和数多这个蛋白质的别的产品。
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Human Polyclonal DYNC1LI2 Primary Antibody for IP, WB - ABIN947797
Malik, Saito, Takaoka, Miki, Nakanishi: BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein. in Cell cycle (Georgetown, Tex.) 2016
Results suggest that dynein 2 light intermediate chain (D2LIC (显示 DYNC2LI1 抗体)) is a bona fide subunit of cytoplasmic dynein (显示 DYNC1H1 抗体) 2 that may play a role in maintaining Golgi organization by binding cytoplasmic dynein (显示 DYNC1H1 抗体) 2 to its Golgi-associated cargo.
Results suggest that Par3 acts as a cortical factor that tethers microtubules through its association with LIC2 dynein.
Cortically localized dynein, essential for maintaining correct spindle orientation, consists majorly of LIC2-dynein, which interacts with cortical 14-3-3 epsilon (显示 YWHAE 抗体)- zeta and Par3 (显示 F2RL2 抗体), conserved proteins required for orienting the spindle.
This study uncovers a novel functional hierarchy during mitotic checkpoint (显示 BUB3 抗体) inactivation between the closely related but homologous LIC subunits of cytoplasmic dynein (显示 DYNC1H1 抗体).
These results suggest that cytoplasmic dynein (显示 DYNC1H1 抗体) 1 binds to BRCA2 (显示 BRCA2 抗体) through the latter's centrosomal localization signal and BRCA2 (显示 BRCA2 抗体) mediates the cohesion between centrosomes during the S phase, potentially serving as a cell-cycle checkpoint.
although dynein lacking light intermediate chains (LICs) drives microtubule gliding at normal rates, the LICs are required for the formation and maintenance of a bipolar spindle.
using a variety of complementary approaches, our results indicate a novel specific role for the LICs in dynein recruitment to components of the late endocytic pathway.
FIP3 (显示 IKBKG 抗体) was identified as the first membrane-associated interacting-partner for DLIC-2.
Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995
cytoplasmic dynein 1 light intermediate chain 2
, dynein, cytoplasmic 1, light intermediate chain 2
, LIC-2 dynein light intermediate chain 53/55
, dynein light intermediate chain 2, cytosolic
, dynein, cytoplasmic, light intermediate polypeptide 2
, dynein, cytoplasmic, light intermediate chain 2