蛋白简介

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.

Gene names and symbols associated with DUSP5

• dual specificity phosphatase 5 (DUSP5) 抗体
• dual specificity phosphatase 5 (dusp5) 抗体
• dual specificity phosphatase 5 S homeolog (dusp5.S) 抗体
• dual specificity phosphatase 5 (Dusp5) 抗体

• Cpg21 抗体
• DUSP 抗体
• DUSP5 抗体
• Gm337 抗体
• HVH3 抗体
• 显示所有的同义词和别名
• MGC84792 抗体
• wu:fc03b11 抗体
• wu:fc86e02 抗体

Protein level used designations for DUSP5

dual specificity protein phosphatase 5-like , dual specificity phosphatase 5 , dual specificity protein phosphatase 5 , VH1-like phosphatase 3 , dual specificity protein phosphatase hVH3 , serine/threonine specific protein phosphatase , MAP-kinase phosphatase (cpg21) , MAP-kinase phosphatase CPG21 , candidate plasticity-related gene 21