(Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))
The product of this gene is a membrane-associated guanylate kinase. The encoded protein may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Mar 2013].
Bongiorno-Borbone, Kadaré, Benfenati, Girault: "FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3." in: Biochemical and biophysical research communications, Vol. 337, Issue 2, pp. 641-6, (2005) (PubMed).
Kindler, Rehbein, Classen, Richter, Böckers: "Distinct spatiotemporal expression of SAPAP transcripts in the developing rat brain: a novel dendritically localized mRNA." in: Brain research. Molecular brain research, Vol. 126, Issue 1, pp. 14-21, (2004) (PubMed).
Ranta, Zhang, Ross, Takkunen, Hirvasniemi, de la Chapelle, Gilliam, Lehesjoki: "Positional cloning and characterisation of the human DLGAP2 gene and its exclusion in progressive epilepsy with mental retardation." in: European journal of human genetics : EJHG, Vol. 8, Issue 5, pp. 381-4, (2000) (PubMed).
Takeuchi, Hata, Hirao, Toyoda, Irie, Takai: "SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density." in: The Journal of biological chemistry, Vol. 272, Issue 18, pp. 11943-51, (1997) (PubMed).
Aliases for DLGAP2 抗体
DLG associated protein 2 (DLGAP2) 抗体 disks large-associated protein 2 (LOC463960) 抗体 discs, large (Drosophila) homolog-associated protein 2a (dlgap2a) 抗体 discs, large (Drosophila) homolog-associated protein 2 (DLGAP2) 抗体 disks large-associated protein 2 (LOC100447448) 抗体 DLG associated protein 2 (Dlgap2) 抗体 discs, large (Drosophila) homolog-associated protein 2 (Dlgap2) 抗体 6430596N04Rik 抗体 DAP2 抗体 PSD-95 抗体 SAPAP2 抗体 Sapap2 抗体