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Deoxyuridine Triphosphatase ELISA试剂盒

(Deoxyuridine Triphosphatase (DUT))
This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19. [provided by RefSeq, Jul 2008].
Deoxyuridine Triphosphatase (DUT) ELISA 试剂盒 Deoxyuridine Triphosphatase (DUT) ELISA 试剂盒 Deoxyuridine Triphosphatase (DUT) ELISA 试剂盒 (ABIN6966332)

DUT 适用: 人 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate

Deoxyuridine Triphosphatase (DUT) ELISA 试剂盒 (ABIN1129512)

DUT 适用: 大鼠 Colorimetric 78-5000 pg/mL

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Popular Deoxyuridine Triphosphatase ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966332
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1129512
Quantity 96 tests
Datasheet Datasheet

Aliases for Deoxyuridine Triphosphatase ELISA试剂盒

deoxyuridine triphosphatase (DUT) ELISA试剂盒
Deoxyuridine triphosphatase (dUTPase) ELISA试剂盒
deoxyuridine triphosphatase (P18) ELISA试剂盒
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