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CYP2E1 encodes a member of the cytochrome P450 superfamily of enzymes. 再加上,我们可以发Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 试剂盒 (42) 和 Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 蛋白 (22)和数多这个蛋白质的别的产品。
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Human Polyclonal CYP2E1 Primary Antibody for IF, IHC - ABIN1534388 : Umeno, McBride, Yang, Gelboin, Gonzalez: Human ethanol-inducible P450IIE1: complete gene sequence, promoter characterization, chromosome mapping, and cDNA-directed expression. in Biochemistry 1989 (PubMed) Show all 2 references for ABIN1534388
Human Polyclonal CYP2E1 Primary Antibody for ELISA, IHC - ABIN4302103 : Niu, Yuan, Leng, Pang, Gu, Chen: CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls. in Medical oncology (Northwood, London, England) 2011 (PubMed)
Chicken Polyclonal CYP2E1 Primary Antibody for WB - ABIN2776801 : Dey, Kessova, Cederbaum: Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1. in Archives of biochemistry and biophysics 2006 (PubMed)
Human Polyclonal CYP2E1 Primary Antibody for IHC, IHC (p) - ABIN4302104 : Fagerberg, Hallström, Oksvold, Kampf, Djureinovic, Odeberg, Habuka, Tahmasebpoor, Danielsson, Edlund, Asplund, Sjöstedt, Lundberg, Szigyarto, Skogs, Takanen, Berling, Tegel, Mulder, Nilsson, Schwenk et al.: Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. ... in Molecular & cellular proteomics : MCP 2014 (PubMed)
Human Polyclonal CYP2E1 Primary Antibody for IHC, IHC (p) - ABIN4302106 : Hou, Bukong, Kodys, Szabo: Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells. in Alcoholism, clinical and experimental research 2013 (PubMed)
The localization of CYP1A2 (显示 CYP1A2 抗体), CYP2B4 and CYP2E1 within the ER was determined by partial membrane solubilization with Brij 98
This meta-analysis suggests that there is an increased risk of antituberculosis drug-induced hepatotoxicity in individuals carrying the C1/C1 genotype of the CYP2E1 RsaI/PstI (显示 SPINK1 抗体) polymorphism; however, no association was found for the DraI polymorphism
NS5A contributes to reactive oxygen species production by activating expression of NADPH (显示 NQO1 抗体) oxidases 1 and 4 as well as cytochrome P450 2E1.
This meta-analysis suggests that the CYP2E1 polymorphisms contributed to the susceptibility of nasopharyngeal carcinoma, especially in Asian populations.
Study indicate that ALDH2 (显示 ALDH2 抗体) Glu487Lys and CYP4502E1 polymorphisms could be risk factors for the development of gastric cancer in the Chinese population.
genetic association studies in population in Italy: Data suggest that SNPs in CYP2E1 are associated with differentiated thyroid carcinoma.
CYP2E1 RsaI/PstI (显示 SPINK1 抗体) polymorphisms may modify the susceptibility to HNC (显示 MMP8 抗体), particularly among Asians, mixed population, and never-smokers.
CYP2E1 rs2031920 and COMT (显示 COMT 抗体) rs4680 are not major contributors to lung cancer risk.
Single nucleotide polymorphism in CYP2E1 gene is Associated with Breast Cancer.
background prevalence of CYP2E1*B polymorphism and their activity in Western Indian population was observed. The study suggests no association between the CYP2E1 genotyping with antituberculous drug-induced hepatotoxicity
This meta-analysis suggests that the CYP2E1 RsaI/PstI (显示 SPINK1 抗体) polymorphisms are a risk factor for developing oral cancer
Data, including data from studies in knockout mice, suggest that the oxidative metabolism of 1,2-dichloropropane, a carcinogenic solvent/insecticide, is exclusively catalyzed by Cyp2e1; this biotransformation step is indispensable for manifestation of hepatotoxic effect of the solvent.
Taken together, these results suggested that 1,2-dichloroethane (1,2-DCE (显示 DHCR24 抗体)) could enhance CYP2E1 protein expression and enzymatic activity, which could cause oxidative damage in liver, serving as an important mechanism underlying 1,2-DCE (显示 DHCR24 抗体)-induced liver damage
CYP2E1 is important in causing aging-dependent hepatic steatosis, apoptosis and fibrosis possibly through increasing nitroxidative stress.
Our results support a significant role for CYP2E1 as a novel 4-Aminobiphenyl N-oxidizing enzyme in adult mice
Schisandrol B protects against APAP-induced liver injury, potentially through inhibition of CYP2E1/3A11-mediated APAP bioactivation and regulation of the p53 (显示 TP53 抗体), p21 (显示 D4S234E 抗体), CCND1 (显示 CCND1 抗体), PCNA (显示 PCNA 抗体), and BCL-2 (显示 BCL2 抗体) to promote liver regeneration.
Studied hepatic stellate cell cytoglobin (显示 CYGB 抗体) involvement in acetaminophen induced hepatotoxicity through the regulation of CYP2E1.
Data suggest that expression of Cyp2e1 in adipose tissue can be regulated by dietary factors; here, expression of Cyp2e1 in white adipose tissue is down-regulated in obesity caused by high-fat diet.
The Cyp2e1-null mice displayed a susceptibility to lung toxicity of styrene similar to that of the wild-type animals; however, Cyp2f2-null mice were resistant to styrene-induced pulmonary toxicity.
significant increases in Col1a1 (显示 COL1A1 抗体), serine/threonine-protein kinase 1, Ctnnb1 (显示 CTNNB1 抗体), CSRNP1 (显示 CSRNP1 抗体), Ddit4 (显示 DDIT4 抗体), Cyp2e1, and Krit1 (显示 KRIT1 抗体) expressions and great decreases inreceptor D2, Neu1 (显示 NEURL 抗体), and Dhcr7 (显示 DHCR7 抗体) expressions following long-term exposure to TiO2 NPs (显示 NPS 抗体)
ATF4 (显示 ATF4 抗体) expression in the liver is responsible for the protective effects against high fat diet-induced CYP2E1 expression.
A highly significant association was found between variation in skatole levels and SNPs within the CYP2E1 gene on chromosome 14.
The relationship between a single nucleotide polymorphism of CYP2E1 and boar taint in pork from Belgian swine is reported.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
cytochrome P450 2E1 , 4-nitrophenol 2-hydroxylase , Cytochrome P450 2E1 , Cytochrome P450 LM3A , Cytochrome P450 isozyme 3A , Cytochrome P450-ALC , Cytochrome P450-J , cytochrome P-450j , CYPIIE1 , cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 , cytochrome P450-J , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , cytochrome P450, 2e1, ethanol inducible , cytochrome P450-ALC , P450-J , P450RLM6 , cytochrome P450 subfamily 2e1 (ethanol-inducible) , cytochrome P450, subfamily 2E, polypeptide 1 , cytochrome P450RLM6 , cytochrome P-450-J , cytochrome P450 CYP2E1