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The protein encoded by CNIH2 is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. 再加上，我们可以发Cornichon Homolog 2 (Drosophila) 蛋白 (6)和数多这个蛋白质的别的产品。
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Cornichon-2 and cornichon-3 (显示 CNIH3 抗体) dictate subunit-specific AMPA (显示 GRIA3 抗体) receptor trafficking and synaptic transmission.
Transmembrane AMPA (显示 GRIA3 抗体) receptor regulatory proteins and cornichon-2 allosterically regulate AMPA (显示 GRIA3 抗体) receptor antagonists and potentiators.
Cornichon homolog 2 (CNIH-2) associates with TARP gamma-8 (显示 CACNG8 抗体) in hippocampus postsynaptic densities; CNIH-2 protein levels are diminished in transmembrane AMPA (显示 GRIA3 抗体) receptor regulatory protein (显示 TGFB1 抗体) (TARP) gamma-8 (显示 CACNG8 抗体) knockout mice.
Significant upregulation of CNIH-2 mRNA expression was found in schizophrenia.
The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants.
, protein cornichon homolog 2
, cornichon homolog 2
, cornichon homolog 3
, cornichon homolog 2 (Drosophila)
, cornichon homolog 2-like
, Cornichon family AMPA receptor auxiliary protein 2
, rotein cornichon homolog 2