anti-Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) 抗体

The protein encoded by CDC27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. 再加上,我们可以发和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CDC27 996 P30260
CDC27 217232 A2A6Q5
CDC27 360643 Q4V8A2
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antibodies-online.cn销售最多的anti-CDC27 抗体

Showing 10 out of 146 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-CDC27 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  NCI-H226 cell lysate. CDC27 is strongly supported by BioGPS gene expression data to be expressed in NCI-H226 WB Suggested Anti-CDC27  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: NCI-H226 cell lysate.CDC27 is strongly supported by BioGPS gene expression data to be expressed in NCI-H226 100 μL 2至3个工作日
$289.00
详细
Cow 非结合性 WB 100 μL 2至3个工作日
$289.00
详细
Cow 非结合性 IP, IHC, WB Immunohistochemical analysis of CDC27 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of CDC27 expression in A549 (A), K562 (B), Jurkat (C), HEK293T (D), HeLa (E) whole cell lysates. 200 μL 13至14个工作日
$487.50
详细
Chimpanzee 非结合性 EIA, WB   0.1 mg 4至8个工作日
$632.50
详细
非结合性 ELISA, WB Western blot analysis of extracts from HuvEc/HepG2/COLO205 cells, using H-NUC Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2至3个工作日
$302.50
详细
非结合性 ELISA, IHC, WB 100 μL Available
$363.46
详细
Cow 小鼠 非结合性 EIA, IHC (p), IP, WB 0.1 mg 6至8个工作日
$313.50
详细
小鼠 非结合性 ELISA, IHC, WB Figure 1: Western blot analysis using CDC27 mouse mAb against CDC27(AA: 724-830)-hIgGFc transfected HEK293 cell. Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer tissues (left) and colon cancer tissues (right) using CDC27 mouse mAb with DAB staining. Dilution: 1/200 - 1/1000 100 μL 8至11个工作日
$491.79
详细
Cow 非结合性 WB 100 μL 11至14个工作日
$551.83
详细
非结合性 ELISA, IHC, IHC (p), WB Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.05 mg 11至14个工作日
$484.00
详细

引用最多的anti-CDC27 抗体

  1. Dog (Canine) Polyclonal CDC27 Primary Antibody for IP, ELISA - ABIN550486 : Wassmann, Benezra: Mad2 transiently associates with an APC/p55Cdc complex during mitosis. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 3 Pubmed References

  2. Cow (Bovine) Polyclonal CDC27 Primary Antibody for IP, ELISA - ABIN550487 : Topper, Campbell, Tugendreich, Daum, Burke, Hieter, Gorbsky: The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis. in Cell cycle (Georgetown, Tex.) 2002 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal CDC27 Primary Antibody for IHC, ELISA - ABIN969035 : Goto, Eddy: Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal CDC27 Primary Antibody for ICC, IF - ABIN4296917 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

  5. Human Monoclonal CDC27 Primary Antibody for IHC, ELISA - ABIN965835 : Koloteva-Levine, Pinchasi, Pereman, Zur, Brandeis, Elroy-Stein: The Apc5 subunit of the anaphase-promoting complex/cyclosome interacts with poly(A) binding protein and represses internal ribosome entry site-mediated translation. in Molecular and cellular biology 2004 (PubMed)
    Show all 2 Pubmed References

更多抗CDC27的相互作用对抗体

Human Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) interaction partners

  1. CDC27 facilitated cells invasion and metastasis via Twist pathway, leading to initiation of epithelial-mesenchymal transition and silencing of Twist expression could reverse this process.

  2. mir-218-2 promotes glioblastomas growth, invasion and drug resistance by targeting CDC27 expression.

  3. The levels of CDC20 and CylinB1 increased and the levels of Ku70 and APC3 decreased after irradiation. APC/C(Cdh1) is involved in regulation of radiosensitivity in human NPC CNE-1 cells.

  4. Data indicate that UBE2S and APC3 co-regulate the expression level of P21 at G2/M check point via the ubiquitin-proteasome system.

  5. Cdc27 is a novel binding partner of Elmo1.Cdc27-Elmo1 has a cellular role independent from the Elmo-Dock1-Rac signal module.

  6. miR-27a could modulate proliferation and radiosensitivity of TNBC cells. CDC-27 is a direct target of miR-27a and its downregulation conferred increased radioresistance of the cells.

  7. These findings suggested that polymorphisms in cdc27 may contribute to the susceptibility of BC though functional studies are needed to further elucidate the underling mechanisms of the associations

  8. The structures show how one APC16 binds asymmetrically to the symmetric APC3 dimer and, together with biochemistry and prior data, explain how APC16 recruits APC7 to APC3.

  9. Low cdc27 and high securin expression predict short survival for breast cancer patients.

  10. Down-regulation of CDC27 protein is associated with radiation resistance.

  11. Data indicate that additional density present in the anaphase-promoting complex (APC/C) structure, proximal to Apc3/Cdc27 of the (tetratricopeptide repeat) lobe, is assigned to the TPR subunit Apc7, a subunit specific to vertebrate APC/C.

  12. the biochemical, structural, and cellular determinants of the novel interaction between MCPH1 and Cdc27 and suggest that this interaction may occur within the larger context of MCPH1-APC/C.

  13. phosphorylation of Cdc27 by CKII is involved in TGF-beta-induced activation of APC.

  14. Cdc20 requires APC3 and APC8 to bind and activate the APC/C when the spindle assembly checkpoint is satisfied, but only APC8 when active, and APC10 is crucial for the destruction of cyclin B1 and securin, but not cyclin A

  15. the spindle checkpoint may regulate CDC27/APC activity at mitosis

  16. HOXC10 co-immunoprecipitates the APC subunit CDC27, and its in vitro degradation is reduced in APC-depleted extracts or by competition with the APC substrate cyclin A.

  17. The interaction is direct and is mediated by the tandem BRCA1 C-terminal domains of MDC1 and the C terminus of the Cdc27 (APC3) subunit of the anaphase-promoting complex/cyclosome.

Mouse (Murine) Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) interaction partners

  1. Cdc27 directs cyclin D1 to alternative degradation by anaphase promoting complex/cyclosome.

CDC27 抗原简介

蛋白简介

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CDC27

  • cell division cycle 27 (CDC27) 抗体
  • cell division cycle 27 (cdc27) 抗体
  • cell division cycle 27 (Cdc27) 抗体
  • cell division cycle 27 S homeolog (cdc27.S) 抗体
  • cell division cycle protein 27 homolog (LOC100123129) 抗体
  • anaphase-promoting complex subunit Apc3 (nuc2) 抗体
  • AI452358 抗体
  • ANAPC3 抗体
  • APC3 抗体
  • BC023187 抗体
  • CDC27 抗体
  • CDC27Hs 抗体
  • D0S1430E 抗体
  • D17S978E 抗体
  • HNUC 抗体
  • NUC2 抗体
  • NV10210 抗体
  • wu:fb54g06 抗体
  • wu:fc88c12 抗体

Protein level used designations for CDC27

CDC27 homolog , H-NUC , anaphase promoting complex subunit 3 , anaphase-promoting complex subunit 3 , anaphase-promoting complex, protein 3 , cell division cycle 27 homolog , cell division cycle protein 27 homolog , nuc2 homolog , cell division cycle 27 homolog (S. cerevisiae) , 20S cyclosome/APC complex protein apc3 , Nuclear alteration protein 2 , Nuclear scaffold-like protein p76 , cell division cycle protein 27

GENE ID SPECIES
996 Homo sapiens
30450 Danio rerio
454815 Pan troglodytes
540660 Bos taurus
779925 Xenopus (Silurana) tropicalis
217232 Mus musculus
360643 Rattus norvegicus
419960 Gallus gallus
443994 Xenopus laevis
490924 Canis lupus familiaris
717321 Macaca mulatta
100025278 Monodelphis domestica
100054552 Equus caballus
100123129 Nasonia vitripennis
100444022 Pongo abelii
100594961 Nomascus leucogenys
100731091 Cavia porcellus
2542438 Schizosaccharomyces pombe 972h-
100345196 Oryctolagus cuniculus
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