anti-Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) 抗体

regulatory(beta) subunit of casein kinase II\; plays a role as a docking site for a subset of CK2 substrates [RGD, Feb 2006].. 再加上,我们可以发Casein Kinase 2, alpha Prime Polypeptide 蛋白 (11)Casein Kinase 2, alpha Prime Polypeptide 试剂盒 (9)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CSNK2A2 1459 P19784
CSNK2A2 13000 O54833
CSNK2A2 307641  
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Showing 10 out of 87 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-CSNK2A2 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL 2至3个工作日
Cow 非结合性 WB WB Suggested Anti-CSNK2A2 Antibody Titration: 0.2-1 ug/mlPositive Control: MCF7 cell lysate 100 μL 2至3个工作日
小鼠 非结合性 FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of HepG2 cells using CSNK2A2 mouse mAb (green) and negative control (red) . 100 μL 3至4个工作日
小鼠 非结合性 ELISA, FACS, IHC, IHC (p) 100 μL 11至14个工作日
非结合性 IHC, WB Immunohistochemistry of paraffin-embedded human liver cancer using CSNK2A2 antibody at dilution of 1:100 (400x lens). 100 μL 11至13个工作日
Bat 非结合性 WB 100 μL 11至14个工作日
Bat 非结合性 IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL 11至14个工作日
非结合性 ELISA, IHC, WB Western blot analysis of Hela whole cell lysates, using CSNK2A2 Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276767 at 1/100 staining Rat lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11至12个工作日
小鼠 非结合性 IF, ELISA, WB Detection limit for recombinant GST tagged CSNK2A2 is approximately 0.3ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg 11至12个工作日
Biotin ELISA, IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μg 11至14个工作日

引用最多的anti-Casein Kinase 2, alpha Prime Polypeptide 抗体

  1. Human Monoclonal CSNK2A2 Primary Antibody for FACS, ELISA - ABIN1098114 : Chemnitz, Pieper, Grüttner, Hauber: Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression. in European journal of immunology 2009 (PubMed)
    Show all 2 Pubmed References

更多抗Casein Kinase 2, alpha Prime Polypeptide的相互作用对抗体

Human Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) interaction partners

  1. Multiple conformations of kinase II subunit alpha (CK2alpha) hinge region, located near the active site, were observed during the dynamics.

  2. The influence of the combined treatment on apoptosis in leukemia cells, as well as on cell-cycle progression and the levels of TS, CK2alpha and P-Ser529-p65 were determined.

  3. CK2 is required to mediate FXR SUMOylation.

  4. this study shows that breakpoint cluster region protein regulates inflammation development via the alpha subunit of casein kinase II

  5. we identify a therapeutically exploitable posttranslational mechanism by which CK2alpha-mediated degradation of BRMS1 promotes metastases in lung cancer

  6. These data support a role for casein kinase 2 in regulation of protein synthesis by downregulating stress granule formation through G3BP1.

  7. In this study, the disordered feature of Nopp140 and the effect of CK2alpha on the structure of Nopp140 were examined using single-molecule fluorescence resonance energy transfer (smFRET) and electron paramagnetic resonance (EPR).

  8. KLF4 acts as a tumor suppressor or oncogene to activate or repress target gene transcription depending on its acetylation status, which is regulated by p21 and CK2 interaction-mediated HDAC2 phosphorylation

  9. results suggest that CK2alpha might play an oncogenic role in hepatocellular carcinoma

  10. CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and may have role in malignant B-cell growth.

  11. We conclude that this class of chimeric peptides, in addition to altering some properties of CK2 holoenzyme, affects several other cellular targets, causing profound perturbations of cell biology

  12. Over-expressed CK2alpha positively regulate Hh/Gli1 signaling in human mesothelioma.

  13. we propose that Foxc2 is functionally maintained in the cytoplasm of normal epithelial cells by CK2alpha/alpha'-mediated phosphorylation at serine 124, which is dependent on proper targeting of the holoenzyme via the CK2b regulatory subunit.

  14. Data suggest casein kinase II (CK2) inhibitors indeno[1,2-b]indole-9,10-dione, which also inhibited the breast cancer resistance protein ABCG2, might be a good therapeutic strategy to improve anticancer drug efficiency.

  15. CSNK2A2 phosphorylates telomeric repeat binding factor 1 and plays an important role for regulation of telomere length.

  16. CK2alpha' exhibits a striking preference for caspase-3 phosphorylation in cells as compared to CK2alpha and that CK2beta exhibits the capacity to abolish caspase-3 phosphorylation

  17. In hsCK2alpha' an open conformation of the interdomain hinge/helix alphaD region that is critical for ATP-binding is found corresponding to an incomplete catalytic spine. In contrast hsCK2alpha often adopts the canonical, PKA-like version of the catalytic spine.

  18. Lack of DNA-PKcs is accompanied by an increase in the protein level of one of the catalytic isozymes of protein kinase CK2, i.e., CK2alpha' and a concomitant increase in CK2 activity.

  19. A thorough investigation of CK2alpha identifies key energetic hot spots on the surface of CK2alpha and their thermostability and catalytic activity in comparison to the wild type subunit.

  20. Data presented the crystal structures of CK2alpha in complex with CX-4945 and adenylyl phosphoramidate at 2.7 and 1.3 A, respectively.

Mouse (Murine) Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) interaction partners

  1. Phosphosites notoriously generated by CK2 are not fully abrogated in CK2 alpha/alpha'((-/-)) cells, while some phosphosites unrelated to CK2 are significantly altered. CK2 promotes phosphoproteomics perturbations attributable to kinases other than CK2.

  2. We found that C/EBPbeta is phosphorylated by CK2 under AMPK suppression and ER stress, which are important from the viewpoint of the worsening pathological condition of type 2 diabetes, such as decreased insulin secretion and apoptosis of pancreatic beta cells/

  3. Data (including data from studies using knockout mice) suggest that Brg1 is phosphorylated by casein kinase 2 (Ck2; Ck2alpha1 and Ck2alpha-prime are catalytic subunits) in proliferating skeletal myoblasts; Brg1 is catalytic subunit of SWI/SNF chromatin-remodeling enzymes; Ck2-mediated phosphorylation of Brg1 appears to regulate myoblast proliferation. (Brg1 = Brahma-related gene 1 protein)

  4. data implicate CK2 as a regulator of the Th17/Treg axis and Th17 cell maturation and suggest that CK2 could be targeted for the treatment of Th17 cell-driven autoimmune disorders.

  5. CD5-CK2 signaling axis regulates positive selection by modulating activation of ERK and promoting survival independent of proximal TCR signals

  6. This study shows for the first time that LPS inhibits colonic biotin uptake via decreasing membrane expression of its transporter and that these effects likely involve a CK2-mediated pathway.

  7. CK2.1 peptide drives chondrogenesis and cartilage formation without induction of chondrocyte hypertrophy by releasing CK2 from distinct sites at BMPRIa

  8. showed that inhibition of CK2 greatly enhanced M3R-stimulated insulin secretion in human islets

  9. CK2-regulated IQJC-SCHIP-1 association with AnkG contributes to axon initial segment maintenance.

  10. We suggest that L1 stimulates neuritogenesis by activating CK2alpha leading to decreased levels of PTEN and p53 via a novel, L1-triggered and CK2alpha-mediated signal transduction pathway.

  11. our results identify CK2 as a novel regulator of TBK1 and IRF3 and suggest that targeting CK2 by small molecular inhibitor may be a viable approach to prevent and treat viral infections.

  12. Cytokine-induced activation of NFkappaB in beta cells is dependent on CK2 activity, which phosphorylates NFkappaB p65 at serine 529.

  13. we investigated whether PAF could induce NF-kappaB activation and tumour metastasis via enhancing CK2 activity.

  14. Data indicate that CD5-casein kinase 2 (CK2) signaling is necessary for efficient nuclear localization of orphan nuclear receptor ROR-gammaT (RORgammat).

  15. Phosphorylation of CFTR at Thr1471 by CK2 correlates with decreased stability of the protein.

  16. CK2 phosphorylation of papillomavirus E2 is a negative regulator of viral DNA replication during latent viral replication.

  17. These observations identify CK2 as a key regulator of homeostatic properties of the intestinal epithelium that serves to promote wound healing, in part through inhibition of apoptosis under conditions of inflammation.

  18. upon BDNF signaling PACSIN 1 is phosphorylated by CK2 which is essential for spine formation

  19. These results indicate CK2 to be linked with unfolded protein response and to resist endoplasmic reticulum stress by activating the XBP-1-GRP78 arm of UPR.

  20. results indicate CK2 is crucial for osteoblast differentiation and could be a target for future therapeutics of fracture healing

Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) 抗原简介


regulatory(beta) subunit of casein kinase II\; plays a role as a docking site for a subset of CK2 substrates

Gene names and symbols associated with CSNK2A2

  • casein kinase 2 alpha 2 (CSNK2A2) 抗体
  • casein kinase 2, alpha prime polypeptide (Csnk2a2) 抗体
  • casein kinase 2 alpha 2 (Csnk2a2) 抗体
  • casein kinase 2 alpha 2 L homeolog (csnk2a2.L) 抗体
  • casein kinase 2 alpha 2 (csnk2a2) 抗体
  • casein kinase 2, alpha prime polypeptide a (csnk2a2a) 抗体
  • casein kinase 2, alpha prime polypeptide (CSNK2A2) 抗体
  • 1110035J23Rik 抗体
  • C77789 抗体
  • CK2 抗体
  • ck2a2 抗体
  • csnk2a1 抗体
  • CSNK2A2 抗体
  • wu:fi09h12 抗体

Protein level used designations for CSNK2A2

CK II alpha' , casein kinase II subunit alpha' , casein kinase II, alpha 2, polypeptide , casein kinase 2, alpha prime polypeptide , casein kinase II subunit alpha'-like , casein kinase 2 alpha 2 , ck2 alpha' , etID309898.7 , CK II , casein kinase II, alpha' subunit , LOW QUALITY PROTEIN: casein kinase II subunit alpha'

1459 Homo sapiens
13000 Mus musculus
282420 Bos taurus
307641 Rattus norvegicus
432180 Xenopus laevis
454131 Pan troglodytes
478108 Canis lupus familiaris
493442 Xenopus (Silurana) tropicalis
712455 Macaca mulatta
100388528 Callithrix jacchus
30488 Danio rerio
100513017 Sus scrofa
415626 Gallus gallus
100719884 Cavia porcellus
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