anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) 抗体

CEACAM1 encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. 再加上,我们可以发Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) 蛋白 (36)Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) 试剂盒 (35)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CEACAM1 634 P13688
CEACAM1 81613 P16573
CEACAM1 26365 P31809
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antibodies-online.cn销售最多的anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) 抗体

Showing 10 out of 326 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 FACS, IF, IF/ICC Flow cytometric analysis of mouse SEMA4D (CD100) expression on splenocytes. 100 μg Log in to see 14至16个工作日
$273.90
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小鼠 非结合性 cELISA, FACS, IHC (fro) Specificity testing of GM8G5. BOSC cells were transiently transfected with expression vectors containing the cDNA of either CEACAM1, 3, 4, 5, 6, 7 or 8. Expression of the constructs was tested with monoclonal antibodies known to recognise the correspondi GM8G5 on renal cell carcinoma (RCC). Hybridoma supernatant of GM8G5 recognises CEACAM1 expressed on the surface of native RCC (orange curve) and on RCC stimulated with IFN-gamma (red curve). PBS served as negative control (black curve) 100 μg Log in to see 6至7个工作日
$453.70
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小鼠 非结合性 IHC (p), WB Anti-CEA antibody (monoclonal), IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti-CEA antibody (monoclonal), IHC(P) IHC(P): Human Rectal Cancer Tissue 100 μg Log in to see 4至6个工作日
$280.00
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小鼠 非结合性 EIA, FACS, IHC (fro), IF Fig. 1: Specificity testing of GM8G5. BOSC cells were transiently transfected with expression vectors containing the cDNA of either CEACAM1, 3, 4, 5, 6, 7 or 8. Expression of the constructs was tested with monoclonal antibodies known to recognise the corresponding proteins (B, coloured curves, D14HD11, BAC2, 80H3), an irrelevant monoclonal antibody served as negative control (red curves). For specificity testing (A), GM8G5 hybridoma supernatant was tested on all CEACAM transfectants. A positive signal was obtained only with CEACAM1 transfected cells (purple curve). Fig. 2: GM8G5 on renal cell carcinoma (RCC). Hybridoma supernatant of GM8G5 recognises CEACAM1 expressed on the surface of native RCC (orange curve) and on RCC stimulated with IFN (red curve). PBS served as negative control (black curve). 0.1 mg Log in to see 6至8个工作日
$456.50
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小鼠 非结合性 ELISA, FACS, ICC, IF, IHC, IHC (fro), IHC (p), IP, WB Immunohistochemistry-Paraffin: CEACAM-1/CD66a Antibody (COL-1) [NBP2-29454] - Formalin-fixed, paraffin-embedded human colon cancer stained with CEA COL-1 antibody at 1:200 using peroxidase-conjugate and DAB chromogen. Immunohistochemistry-Paraffin: CEACAM-1/CD66a Antibody (COL-1) [NBP2-29454] - Staining of colon cancer. 0.1 mg Log in to see 7至9个工作日
$488.73
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小鼠 PE FACS Detection of CEACAM-1/CD66a in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human Fc gamma RIII (CD16) CFS-conjugated Monoclonal Antibody. 100 Tests Log in to see 8至9个工作日
$319.79
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大鼠 非结合性 ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Rat Liver Tissue. 100 μg Log in to see 15至18个工作日
$380.00
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非结合性 IHC, IHC (p) Anti-CEACAM1 antibody  ABIN1048423 IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11至14个工作日
$484.00
详细
非结合性 WB Western blot analysis of CD66a expression in A549 (A), HT29 (B), SW620 (C), mouse liver (D), mouse kidney (E) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
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非结合性 ELISA, WB Western blot analysis of CD66 (Phospho-Ser508) using Calc LOVO whole cell lysates 100 μL Log in to see 11至12个工作日
$450.00
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引用最多的anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) 抗体

  1. Human Monoclonal CEACAM1 Primary Antibody for EIA, FACS - ABIN114594 : Hammarström: The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. in Seminars in cancer biology 1999 (PubMed)
    Show all 11 Pubmed References

  2. Human Monoclonal CEACAM1 Primary Antibody for FACS - ABIN4897487 : Gebauer, Wicklein, Tachezy, Grob, Steinemann, Manukjan, Göhring, Schlegelberger, Maar, Izbicki, Bockhorn, Schumacher: Establishment and Characterization of a Pair of Patient-derived Human Non-small Cell Lung Cancer Cell Lines from a Primary Tumor and Corresponding Lymph Node Metastasis. in Anticancer research 2016 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal CEACAM1 Primary Antibody for FACS - ABIN2689373 : Kuroki, Arakawa, Matsuo, Oikawa, Misumi, Nakazato, Matsuoka: Molecular cloning of nonspecific cross-reacting antigens in human granulocytes. in The Journal of biological chemistry 1991 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal CEACAM1 Primary Antibody for FACS - ABIN2689374 : Siler, Eggensperger, Hand, Milenic, Miller, Houchens, Hinkle, Schlom: Therapeutic efficacy of a high-affinity anticarcinoembryonic antigen monoclonal antibody (COL-1). in Biotechnology therapeutics 1994 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal CEACAM1 Primary Antibody for CyTOF, FACS - ABIN4900284 : Rahmoun, Molès, Pedretti, Mathieu, Fremaux, Raison-Peyron, Lecron, Yssel, Pène: Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils. in The Journal of investigative dermatology 2009 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal CEACAM1 Primary Antibody for IHC (p), WB - ABIN3043635 : Li, Chen, Zeng, Li, Zhang, Lin, Zhang, Xie, He, Shu, Yang, Tang, Fu: Matrigel basement membrane matrix induces eccrine sweat gland cells to reconstitute sweat gland-like structures in nude mice. in Experimental cell research 2015 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal CEACAM1 Primary Antibody for FACS - ABIN4897486 : Samineni, Zhang, Shively: Carcinoembryonic antigen-related cell adhesion molecule 1 negatively regulates granulocyte colony-stimulating factor production by breast tumor-associated macrophages that mediate tumor angiogenesis. in International journal of cancer 2013 (PubMed)

  8. Mouse (Murine) Polyclonal CEACAM1 Primary Antibody for CyTOF, FACS - ABIN4899129 : Schmidt, Woedtke, Stenzel, Lindner, Polei, Vollmar, Bekeschus: One Year Follow-Up Risk Assessment in SKH-1 Mice and Wounds Treated with an Argon Plasma Jet. in International journal of molecular sciences 2017 (PubMed)

更多抗Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein)的相互作用对抗体

Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) interaction partners

  1. These experiments also confirmed that protein levels of CEACAM-1, which functions in cell adhesion, is dependent on LLO biosynthesis in vivo. Kato III cells and the MPDU1-rescued Kato IIIM cells therefore provide a novel model to examine the consequences of defective LLO biosynthesis both in vitro and in vivo.

  2. The MAPK-driven CEACAM1p activity is mediated by ETS1.

  3. CEACAM1 mRNA or protein expression are independent prognostic markers for ovarian cancer carcinomas.

  4. We suggest that CEACAM1 could be a prognostic marker of oral squamous cell carcinoma and oral carcinoma in situ. Our most important finding was that it could help pathologists diagnosing oral carcinoma in situ

  5. GNAS mutation is a highly specific test for IPMN. When GNAS testing is added to CEA and KRAS, a significantly greater overall accuracy (86.2%) is achieved.

  6. CEACAM1 single nucleotide polymorphisms association with lymphedema caused by Wuchereria bancrofti.

  7. HBx, VEGF and CEACAM1 were widely expressed in HBV-related HCC. HBx may facilitate occurrence and progression of HBV-related HCC via down-regulating CEACAM1 and up-regulating VEGF.

  8. these data identify CEACAM1 as a clinically highly interesting target in multiple sclerosis pathogenesis and open new therapeutic avenues for the treatment of the disease.

  9. serum levels of CEACAM1 in healthy pregnant women were much lower than in non-pregnant women

  10. CEACAM1 overexpression significantly suppressed MM cell proliferation, induced cell apoptosis, and inhibited cell invasion and migration possibly through activation of caspase-3 and downregulation of MMP-2 and MMP-9.

  11. Data suggest that the serum level of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) may be used to discriminate gastrointestinal cancer patients from health controls.

  12. In this paper, a dual-target electrochemical aptasensor has been developed for simultaneous detection of carcinoembryonic antigen and mucin-1 based on metal ion electrochemical labels and Ru(NH3)6(3+) electronic wires

  13. Furthermore, the proposed aptasensor was successfully applied in determining CEA in serum samples, showing its superior prospects in clinical diagnosis.

  14. we show here that Human Metapneumovirus (HMPV)-infected cells upregulates CEACAM1 to restrict HMPV infection

  15. Helicobacter pylori HopQ binds the amino-terminal IgV-like domain of human CEACAM1, CEACAM3, CEACAM5 or CEACAM6 proteins, thereby enabling translocation of the major pathogenicity factor CagA into host cells.

  16. Here, the authors identify members of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as receptors of Helicobacter pylori and show that HopQ is the surface-exposed adhesin that specifically binds human CEACAM1, CEACAM3, CEACAM5 and CEACAM6.

  17. Data show that SOX9 regulates CEACAM1 primarily via Sp1 and ETS1.

  18. short cytoplasmic domain isoforms at the primary lesion invasion front associated with recurrence and prognosis of patients with colorectal liver metastasis after curative hepatectomy; expression of CEACAM1-4S enhances the tumor-initiating property of colorectal cancer cells

  19. Results report that CEACAM1 was uniquely expressed at high levels in both human neoplastic mast cells (mastocytosis) and medullary thyroid carcinoma cell (MTC) lines, and suggest that the dominantly interacting proteins SHP1 or SFK determine whether CEACAM1-L displays a positive or negative role in tumor cells. .

  20. SASH1 acts through NOTCH1 and its inhibitor DLK1 in a three-dimensional model of lumenogenesis involving CEACAM1.

Mouse (Murine) Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) interaction partners

  1. CEACAM1 controls epithelial-mesenchymal transition in vitro and in vivo by site-specific regulation of beta-catenin phosphorylation

  2. A 30-day high fat feeding regimen demonstrated that white adipose tissue-derived fatty acids repressed hepatic CEACAM1-dependent regulation of insulin and lipid metabolism in 3-month-old male C57BL/6J mice.

  3. determined the crystal structure of mCEACAM1b and identified the structural differences and additional residue differences between mCEACAM1a and mCEACAM1b that affect MHV binding and entry

  4. REVIEW: summarizes the vascular effects of CEACAM1 and focuses on its role in vascular morphogenesis and endothelial barrier regulation

  5. CEACAM1 exacerbates hypoxic cardiomyocyte injury and post-infarction cardiac remodeling by enhancing cardiomyocyte mitochondrial dysfunction and endoplasmic reticulum stress-induced apoptosis.

  6. The increase in total fat mass in Cc1(-/-) mice is mainly attributed to hyperphagia and reduced spontaneous physical activity. Although the contribution of the loss of CEACAM1 from anorexigenic proopiomelanocortin neurons in the arcuate nucleus is unclear, leptin resistance and elevated hypothalamic fatty-acid synthase activity could underlie altered energy balance in these mice.

  7. Ceacam1 is essential for normal integrin aIIbb3-mediated platelet function; the disruption of mouse Ceacam1 induced moderate integrin aIIbb3-mediated functional defects.

  8. hepatic CEACAM1 expression at fasting is mediated by Pparalpha-dependent mechanisms.

  9. Gram-positive bacteria promote the mRNA expression of CEACAM1 or CEACAM20 in the small intestine. Inflammatory cytokines or butyrate likely participates in such effects of commensal bacteria.

  10. CEACAM1 is a crucial regulator of B-cell survival, influencing B-cell numbers and protective antiviral antibody responses

  11. High-fat diet amplifies the permissive effect of Ceacam1 deletion on renal expression of all renin-angiotensin system components, PI3K phosphorylation, inflammation, and fibrosis.

  12. Ceacam1L acts as a crucial factor in glioblastoma-initiating cell maintenance and tumorigenesis by activating c-Src/STAT3 signaling. Monomers of the cytoplasmic domain of Ceacam1L bound to c-Src and STAT3 and induced their phosphorylation.

  13. CEACAM1 levels in the liver were reduced in prenatally stressed diet-induced obesity offspring after the high fat diet challenge, suggesting that preexisting genetic predisposition combined with prenatal stress increases the risk for obesity in adulthood.

  14. high-fat diet reduced hepatic CEACAM1 expression and that overexpressing CEACAM1 in liver curtailed diet-induced metabolic abnormalities by protecting hepatic insulin clearance.

  15. a physiologic role of CEACAM1 in the regulation of osteoclastogenesis

  16. CD66a and CD117 may be useful markers to isolate several cell types consisting of SMG epithelium and to analyze their molecular and cellular nature.

  17. expression significantly reduced in the colon tissue of mice with ulcerative colitis

  18. This is the first study demonstrating that CEACAM1 enhances vascular remodeling and tuft regression by increasing endothelial resistance to alterations in oxygen tension, thus accelerating vascular recovery after systemic hypoxia.

  19. CEACAM1 serves as a heterophilic ligand for TIM-3 that is required for its ability to mediate T-cell inhibition, and this interaction has a crucial role in regulating autoimmunity and anti-tumour immunity

  20. CEACAM1 controls matrix metalloproteinase-9 secretion by neutrophils in postischemic inflammation at the blood brain barrier after stroke.

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) 抗原简介

蛋白简介

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Gene names and symbols associated with CEACAM1

  • carcinoembryonic antigen related cell adhesion molecule 1 (CEACAM1) 抗体
  • carcinoembryonic antigen-related cell adhesion molecule 1 (ceacam1) 抗体
  • carcinoembryonic antigen related cell adhesion molecule 1 (Ceacam1) 抗体
  • carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) 抗体
  • carcinoembryonic antigen-related cell adhesion molecule 6 (LOC101103343) 抗体
  • bb-1 抗体
  • Bgp 抗体
  • Bgp1 抗体
  • BGPI 抗体
  • BGPR 抗体
  • C-CAM 抗体
  • Cc1 抗体
  • Ccam1 抗体
  • CD66a 抗体
  • Cea-1 抗体
  • Cea-7 抗体
  • Cea1 抗体
  • Cea7 抗体
  • CEACAM1 抗体
  • hm:zeh0068 抗体
  • Hv-2 抗体
  • Hv2 抗体
  • mCEA1 抗体
  • Mhv-1 抗体
  • MHVR 抗体
  • MHVR1 抗体
  • mmCGM1 抗体
  • mmCGM1a 抗体
  • mmCGM2 抗体
  • zeh0068 抗体

Protein level used designations for CEACAM1

CD66a antigen , antigen CD66 , carcinoembryonic antigen-related cell adhesion molecule 1 , ATP-dependent taurocolate-carrier protein , C-CAM 105 , CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin) , GP110 , bone gamma-carboxyglutamic acid (Gla) protein , cell-CAM 105 , ecto-ATPase , osteocalcin , pp120 , pp120/ecto-ATPase , BGP-1 , CEA-related cell adhesion molecule 1 , MHV-R , biliary glycoprotein 1 , biliary glycoprotein D , carcinoembryonic antigen 1 , carcinoembryonic antigen 7 , hepatitis virus (MHV-4) susceptibility , hepatitis virus receptor , murine hepatitis virus receptor , carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) , carcinoembryonic antigen-related cell adhesion molecule 6

GENE ID SPECIES
634 Homo sapiens
114465 Danio rerio
612435 Canis lupus familiaris
81613 Rattus norvegicus
26365 Mus musculus
101103343 Ovis aries
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