CD72 Molecule 蛋白 (CD72)

Plays a role in B-cell proliferation and differentiation.. 再加上,我们可以发CD72 抗体 (160)CD72 试剂盒 (11)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
CD72 12517 P21855
CD72 971 P21854
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Showing 10 out of 21 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
大肠杆菌(E. Coli) 大鼠 His tag,T7 tag 100 μg Log in to see 15至18个工作日
大肠杆菌(E. Coli) His tag,TRX tag   50 μg Log in to see 4 Days
HEK-293 Cells Fc Tag Human CD72, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 2至3个工作日
小麦胚 GST tag 10 μg Log in to see 11至12个工作日
大肠杆菌(E. Coli) His tag,T7 tag 100 μg Log in to see 15至18个工作日
大肠杆菌(E. Coli) 小鼠 His tag,T7 tag 100 μg Log in to see 15至18个工作日
HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
HEK-293 Cells Fc Tag   0.1 mg Log in to see 2至3个工作日

CD72 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine) ,
, ,
Human , , ,
, , , , , , ,
Rat (Rattus)

更多CD72 Molecule (CD72)互动伙伴

Mouse (Murine) CD72 Molecule (CD72) interaction partners

  1. CD72 appears to specifically inhibit B cell response to the endogenous TLR7 (显示 TLR7 蛋白) ligand Sm/RNP (显示 RNPC3 蛋白).

  2. CD72 negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcepsilonRIalpha.

  3. CD5 (显示 CD5 蛋白) and CD72 play a critical role in maintaining regulatory T and B cell homeostasis

  4. These results strongly suggest that the Cd72(c) is a crucial modifier gene that regulates Fas(lpr (显示 FAS 蛋白))-induced autoimmune disease due to its reduced activity of B cell signal regulation.

  5. Cd72 polymorphism affects susceptibility to lupus phenotypes.

  6. Inhibitory coreceptors CD72 and CD22 (显示 CD22 蛋白) are responsible for setting the requirement of CD40 (显示 CD40 蛋白) signaling for survival and proliferation of antigen-stimulated spleen B cells.

  7. results strongly suggest that the apoptosis preventing signal evoked by CD72 ligation is delivered through the pathway of NF-kappaB (显示 NFKB1 蛋白), c-Myc (显示 MYC 蛋白), p27(Kip1 (显示 CDKN1B 蛋白)) and cyclin (显示 PCNA 蛋白)

  8. Strength of B-cell antigen receptor signals is strictly tuned by the interaction of CD100 (显示 SEMA4D 蛋白) with CD72; this interaction is essential for maintaining immunological homeostasis as well as generating a proper immune response.

  9. CD72 plays a dominant role as a negative regulator of BCR (显示 BCR 蛋白) signaling in primary mature B lymphocytes.

  10. CD72 is required to maintain B cell anergy and functions as a regulator of peripheral B cell tolerance

Human CD72 Molecule (CD72) interaction partners

  1. Interferon-alpha (显示 IFNA 蛋白)-induced CD100 (显示 SEMA4D 蛋白) expression on naive CD8 (显示 CD8A 蛋白)(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction.

  2. Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis

  3. CD72 expression on activated B cells of SLE patients was significantly lower than that of normal controls. sema3A (显示 SEMA3A 蛋白) enhanced CD72 expression of B cells, but it was still lower in SLE patients than in normal individuals.

  4. data demonstrated aberrant expression of CD72 exists on B cells of myasthenia gravis and multiple sclerosis patients and expression level of CD72 molecule has a significantly negative correlation with anti-AchR antibody levels in myasthenia gravis

  5. CD72 mRNA expression level correlates with Sema4D (显示 SEMA4D 蛋白) expression in peripheral blood mononuclear cells in immune thrombocytopenia.

  6. CD100 (显示 SEMA4D 蛋白), CD72 and CD45 (显示 PTPRC 蛋白) were expressed in placenta and exhibited different mRNA and protein levels in normal pregnancy and miscarriage. Protein levels were highly dysregulated around 10 weeks of gestation in first and second miscarriage placentas.

  7. CD100 (显示 SEMA4D 蛋白)-CD72 interaction can be the mechanism by which NK cell communicate with B cells.

  8. Data show that ligation of CD72 with the BU40, or with rCD100 negatively regulates KIT-mediated mast cell proliferation, chemotaxis, and chemokine (显示 CCL1 蛋白) production.

  9. results indicated that the presence of CD72-*2 allele decreases risk for human systemic lupus erythematosus conferred by FCGR2B-232Thr, possibly by increasing the AS isoform of CD72

  10. CD72 is a key molecule in regulating mature B cell differentiation; CD72 signaling reduces the expression of X-box binding protein 1 (显示 XBP1 蛋白) in B cells



Plays a role in B-cell proliferation and differentiation.

Gene names and symbols associated with CD72 Molecule 蛋白 (CD72)

  • CD72 antigen (Cd72)
  • CD72 molecule (CD72)
  • CD72b 蛋白
  • CD72c 蛋白
  • Ly-19 蛋白
  • Ly-32 蛋白
  • Ly-m19 蛋白
  • Lyb-2 蛋白
  • LYB2 蛋白

Protein level used designations for CD72 Molecule 蛋白 (CD72)

B-cell differentiation antigen CD72 , lymphocyte antigen 32 , CD72 antigen , lyb-2

12517 Mus musculus
971 Homo sapiens
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