CD72 Molecule 蛋白 (CD72)

Plays a role in B-cell proliferation and differentiation.. 再加上,我们可以发CD72 抗体 (165)CD72 试剂盒 (10)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
CD72 12517 P21855
CD72 971 P21854
CD72    
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Showing 10 out of 20 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
详细
Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
$5,262.31
详细
大肠杆菌(E. Coli) 大鼠 His tag,T7 tag 100 μg Log in to see 15至18个工作日
$733.00
详细
大肠杆菌(E. Coli) His tag,TRX tag   50 μg Log in to see 4 Days
$522.50
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HEK-293 Cells Fc Tag Human CD72, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 2至3个工作日
$319.00
详细
小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$325.44
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大肠杆菌(E. Coli) His tag,T7 tag 100 μg Log in to see 15至18个工作日
$685.00
详细
大肠杆菌(E. Coli) 小鼠 His tag,T7 tag 100 μg Log in to see 15至18个工作日
$698.00
详细
HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
$814.00
详细
HEK-293 Cells Fc Tag   0.1 mg Log in to see 2至3个工作日
$584.38
详细

CD72 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine) ,
, ,
Human , , ,
, , , , , , ,
Rat (Rattus)

更多CD72 Molecule (CD72)互动伙伴

Mouse (Murine) CD72 Molecule (CD72) interaction partners

  1. CD72 appears to specifically inhibit B cell response to the endogenous TLR7 ligand Sm/RNP.

  2. CD72 negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcepsilonRIalpha.

  3. CD5 and CD72 play a critical role in maintaining regulatory T and B cell homeostasis

  4. These results strongly suggest that the Cd72(c) is a crucial modifier gene that regulates Fas(lpr)-induced autoimmune disease due to its reduced activity of B cell signal regulation.

  5. Cd72 polymorphism affects susceptibility to lupus phenotypes.

  6. Inhibitory coreceptors CD72 and CD22 are responsible for setting the requirement of CD40 signaling for survival and proliferation of antigen-stimulated spleen B cells.

  7. results strongly suggest that the apoptosis preventing signal evoked by CD72 ligation is delivered through the pathway of NF-kappaB, c-Myc, p27(Kip1) and cyclin

  8. Strength of B-cell antigen receptor signals is strictly tuned by the interaction of CD100 with CD72; this interaction is essential for maintaining immunological homeostasis as well as generating a proper immune response.

  9. CD72 plays a dominant role as a negative regulator of BCR signaling in primary mature B lymphocytes.

  10. CD72 is required to maintain B cell anergy and functions as a regulator of peripheral B cell tolerance

  11. CD72 is an inhibitory receptor on NK cells regulating cytokine production.

  12. CD72 activates extracellular signal-regulated kinase and c-Jun N-terminal kinase (but not p38 mitogen-activated protein kinase), synergizing with B cell receptor signals to induce proliferation of B cells in X-linked immunodeficiency.

Human CD72 Molecule (CD72) interaction partners

  1. Interferon-alpha-induced CD100 expression on naive CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction.

  2. Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis

  3. CD72 expression on activated B cells of SLE patients was significantly lower than that of normal controls. sema3A enhanced CD72 expression of B cells, but it was still lower in SLE patients than in normal individuals.

  4. data demonstrated aberrant expression of CD72 exists on B cells of myasthenia gravis and multiple sclerosis patients and expression level of CD72 molecule has a significantly negative correlation with anti-AchR antibody levels in myasthenia gravis

  5. regulates serum immunoglobulin leveln and disease resistance in systemic lupus erythematosus

  6. CD72 mRNA expression level correlates with Sema4D expression in peripheral blood mononuclear cells in immune thrombocytopenia.

  7. CD100, CD72 and CD45 were expressed in placenta and exhibited different mRNA and protein levels in normal pregnancy and miscarriage. Protein levels were highly dysregulated around 10 weeks of gestation in first and second miscarriage placentas.

  8. CD100-CD72 interaction can be the mechanism by which NK cell communicate with B cells.

  9. Data show that ligation of CD72 with the BU40, or with rCD100 negatively regulates KIT-mediated mast cell proliferation, chemotaxis, and chemokine production.

  10. results indicated that the presence of CD72-*2 allele decreases risk for human systemic lupus erythematosus conferred by FCGR2B-232Thr, possibly by increasing the AS isoform of CD72

  11. CD72 is a key molecule in regulating mature B cell differentiation; CD72 signaling reduces the expression of X-box binding protein 1 in B cells

  12. increased nucleotide mutation of CD72 mRNA accounts for the decreased expression level of CD72 in B cells, and it might be related to hyperactivity of B cells in patients with SLE

  13. CD72 polymorphisms are associated with age of appearing clinical manifestations in idiopathic thrombocytopenic purpura in Chinese patients.

蛋白简介CD72

蛋白简介

Plays a role in B-cell proliferation and differentiation.

Gene names and symbols associated with CD72 Molecule 蛋白 (CD72)

  • CD72 antigen (Cd72)
  • CD72 molecule (CD72)
  • CD72b 蛋白
  • CD72c 蛋白
  • Ly-19 蛋白
  • Ly-32 蛋白
  • Ly-m19 蛋白
  • Lyb-2 蛋白
  • LYB2 蛋白

Protein level used designations for CD72 Molecule 蛋白 (CD72)

B-cell differentiation antigen CD72 , lymphocyte antigen 32 , CD72 antigen , lyb-2

GENE ID SPECIES
12517 Mus musculus
971 Homo sapiens
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