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BACE1 蛋白

(Beta-secretase 1 (BACE1))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].

23 results

BACE1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7273905
 
BACE1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7273904
 
BACE1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7273906
 
BACE1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
产品编号 ABIN7121998
 
BACE1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1346345
 
BACE1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
产品编号 ABIN7320444
 
BACE1 宿主: 人 宿主: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE.
Pubmed 2 references
产品编号 ABIN2180626
 
BACE1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505103
 
BACE1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % WB, SDS, Imm, PC
产品编号 ABIN7391801
 
BACE1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % WB, SDS, Imm, PC
产品编号 ABIN7411204
 
BACE1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA
产品编号 ABIN7575117
 
BACE1 宿主: 人 宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
产品编号 ABIN7607491
 
BACE1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7391804
 
BACE1 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7391807
 
BACE1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7318053
 
BACE1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7318054
 
BACE1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7318055
 
BACE1 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS, EAA Active
产品编号 ABIN7596290
 
BACE1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2715129
 
BACE1 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, ELISA, IP
产品编号 ABIN3008460
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Enzyme Activity Assay (EAA)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • 适用
    • Human
    • Mouse
    • Rat
    • Cow
    • Guinea Pig
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Yeast
    • Baculovirus infected Insect Cells
    • Mammalian Cells
    • Wheat germ
  • 抗原表位
    • AA 22-457
    • AA 170-428
    • AA 181-366
    • AA 190-430
    • AA 22-429
    • AA 22-460
    • AA 22-501
    • AA 46-152
    • Transcript Variant A
  • 标记
    • His tag
    • 非结合性
    • Fc Tag
    • His tag,GST tag
    • GST tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • 生物活性
    • Biologically Active
  • Supplier
    • antibodies-online
    • CUSABIO
    • ACROBiosystems
    • Abbexa
    • OriGene

Latest Publications for our BACE1 蛋白

Mycroft-West, Devlin, Cooper, Procter, Miller, Fernig, Guerrini, Guimond, Lima, Yates, Skidmore: "Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus." in: Neural regeneration research, Vol. 15, Issue 8, pp. 1546-1553, (2020) (PubMed).

Peters-Libeu, Campagna, Mitsumori, Poksay, Spilman, Sabogal, Bredesen, John: "sAβPPα is a Potent Endogenous Inhibitor of BACE1." in: Journal of Alzheimer's disease : JAD, Vol. 47, Issue 3, pp. 545-55, (2015) (PubMed).

Aliases for BACE1 蛋白

beta-secretase 1 (BACE1) 蛋白
beta-site APP cleaving enzyme 1 (Bace1) 蛋白
beta-secretase 1 (Bace1) 蛋白
beta-site APP-cleaving enzyme 1 (bace1) 蛋白
ASP2 蛋白
BACE 蛋白
Bace 蛋白
BACE1 蛋白
C76936 蛋白
HSPC104 蛋白
MGC145931 蛋白
zgc:77409 蛋白
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