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BCL2A1 encodes a member of the BCL-2 protein family. 再加上，我们可以发BCL2-Related Protein A1 抗体 (116) 和 BCL2-Related Protein A1 蛋白 (12)和数多这个蛋白质的别的产品。
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Crystal structures of anti-apoptotic BFL-1 and its complex with a covalent stapled BH3 peptide inhibitor have been presented.
Demonstrate immunohistochemical expression of Wnt11 and BCL2A1 in complete moles and normal villi.
Bfl-1 was mitochondrially resident in both resting and apoptotic cells and experienced regulation by the proteasome and NFkappaB pathways.
Bcl2a1 overexpressing granulocytic MDSCs demonstrated prolonged survival.
Results indicate that mismatches in minor H antigens HA-8 (KIAA0020) and ACC-1 (BCL2A1) predisposed to chronic graft-versus-host disease (GvHD).
BCL2A1 is a novel marker associated with seizure prognosis following surgery for low-grade brain neoplasms.
MITF-BCL2A1 as a lineage-specific oncogenic pathway in melanoma and underscore its role for improved response to BRAF-directed therapy.
Bcl2a1 should be considered as a proto-oncogene with a potential role in both lymphoid and myeloid leukemogenesis
Mitochondrial antiapoptotic factor Bfl-1 is significantly reduced by suppressor of cytokine signaling (SOCS)1.
results highlight Bfl-1 as a major effector in activation-induced human mast cell survival
Data indicate that BCL2a1 expression enhances tumor cell survival in nervous system (CNS) leading to intracranial tumor growth.
Data demonstrate that calpain-mediated cleavage of full-length Bfl-1 induces the release of C-terminal membrane active alpha-helices that are responsible for its conversion into a pro-apoptotic factor.
neutrophils from patients with sepsis express reduced levels of antiapoptotic Mcl1 and A1
results directly implicate Bfl-1 and Bcl-x(L) in HTLV-1-infected T-cell survival and suggest that both Bfl-1 and Bcl-x(L) represent potential therapeutic targets for ATLL treatment.
The transcription factor Spi-B regulates human plasmacytoid dendritic cell survival through direct induction of the antiapoptotic gene BCL2-A1.
Inhibition of Mcl-1 and A1 strongly induced cell death in some melanoma cell lines.
These findings are the first indication that Bfl-1 plays a crucial role in setting the elevated threshold of resistance of this malignant cell type to apoptosis
Bfl-1 importantly regulates lung cancer cell sensitivity to gemcitabine.
Bfl-1/A1 negatively regulates autophagy and expression of Bfl-1/A1 in H37Rv infected macrophages
Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma.
a high-level expression of BCL2A1 in the conceptus at Day 21 of gestation, and it was expressed and increased in the extraembryonic membrane, cotyledon, and intercotyledon from implantation to term.
regulation of A1 and Bak contribute to mitochondrial membrane stability, reduced caspase-9 activity, and delayed apoptosis in bovine neutrophils exposed to glucocorticoids
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
bcl-2-like protein 5
, bcl-2-related protein A1
, hematopoietic BCL2-related protein A1
, hemopoietic-specific early response protein
, protein BFL-1
, B-cell leukemia/lymphoma 2 related protein A1
, B-cell leukemia/lymphoma 2 related protein A1d
, BCL2-related protein A1d
, protein A1
, Bcl-2-like protein 5
, BCL2-related protein A1
, Bcl-2-related protein A1