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GTPase-activating protein for the ADP ribosylation factor family (Potential). 再加上，我们可以发ADAP2 蛋白 (8)和数多这个蛋白质的别的产品。
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Human Polyclonal ADAP2 Primary Antibody for IHC (p), IHC - ABIN250032
Jenne, Tinschert, Stegmann, Reimann, Nürnberg, Horn, Naumann, Buske, Thiel: A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions. in Genomics 2000
ArfGAP domain-containing protein 2 (ADAP2) is identified as a key novel scaffolding protein that integrates different modules of the RIG-I (显示 DDX58 抗体) pathway, located at distinct subcellular locations, and mediates cellular antiviral type I interferon (显示 IFNA 抗体) production.
Data suggest ADAP2 (an interferon-beta (显示 IFNB1 抗体) stimulated gene) disrupts pathogenic internalization of some RNA viruses/virions (dengue, vesicular stomatitis) by altering ADP ribosylation factor 6 (显示 ARF6 抗体)-mediated processes including up-regulation of pinocytosis.
Centaurin-alpha (显示 ADAP1 抗体) interacts with beta-tubulin (显示 TUBB 抗体) and stabilizes microtubules.
The human gene for centaurin alpha 2 is located on chromosome 17, position 17q11.2, near the neurofibromatosis 1 (NF1 (显示 NF1 抗体)) locus and concentrated at the plasma membrane.
ADAP2 has a role in heart development, and might be a reliable candidate gene for the occurrence of cardiovascular malformations in patients with NF1 (显示 NF1 抗体) microdeletion.
GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity.
centaurin, alpha 2
, ArfGAP with dual PH domains 2
, centaurin-alpha 2 protein
, arf-GAP with dual PH domain-containing protein 2
, centaurin beta
, Centaurin-alpha2 protein