anti-Anaphase Promoting Complex Subunit 15 (ANAPC15) 抗体

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. 再加上,我们可以发Anaphase Promoting Complex Subunit 15 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ANAPC15 25906 P60006
ANAPC15    
ANAPC15    
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Showing 6 out of 8 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB Host: Rabbit Target Name: ANAPC15 Sample Type: HT1080 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2至3个工作日
$289.00
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非结合性 ICC, IF, IHC, IHC (p), WB Western Blot: C11orf51 Antibody [NBP1-84151] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY415516) Immunocytochemistry/Immunofluorescence: C11orf51 Antibody [NBP1-84151] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & vesicles. 0.1 mL Log in to see 10至13个工作日
$491.63
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Cow 非结合性 WB   50 μg Log in to see 7至9个工作日
$551.83
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非结合性 IHC (p), WB Immunohistochemical staining of human appendix with C11orf51 polyclonal antibody  shows strong cytoplasmic positivity in lymphoid cells at 1:200-1:500 dilution. Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate). Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with C11orf51 polyclonal antibody . 100 μL Log in to see 11至12个工作日
$517.50
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非结合性 IHC, ELISA, WB   150 μL Log in to see 13至16个工作日
$753.50
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非结合性 IHC, ELISA, WB   50 μL Log in to see 2至3个工作日
$510.36
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引用最多的anti-Anaphase Promoting Complex Subunit 15 抗体

  1. Human Polyclonal ANAPC15 Primary Antibody for ICC, IF - ABIN4285964 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

更多抗Anaphase Promoting Complex Subunit 15的相互作用对抗体

Human Anaphase Promoting Complex Subunit 15 (ANAPC15) interaction partners

  1. cryo-EM structure of an APC (显示 APC 抗体)/C-Cdh1 (显示 CDH1 抗体) complex with Apc1 (显示 SLC25A24 抗体)(WD40 (显示 DCAF12L2 抗体)) deleted showed that the mutant APC (显示 APC 抗体)/C is locked into an inactive conformation in which the UbcH10 (显示 UBE2C 抗体)-binding site of the catalytic module is inaccessible. Additionally, an EM density for Apc15 is not visible

  2. Anaphase promoting complex subunit 15(APC15) mediates the constant turnover of CDC20 (显示 CDC20 抗体) and mitotic checkpoint (显示 BUB3 抗体) protein complexes, allowing the spindle checkpoint assembly to respond to the attachment state of kinetochores.

  3. APC15 is required for anaphase-promoting complex/cyclosome-bound mitotic checkpoint (显示 BUB3 抗体) complex-dependent CDC20 (显示 CDC20 抗体) autoubiquitylation and degradation and for timely anaphase initiation.

Anaphase Promoting Complex Subunit 15 (ANAPC15) 抗原简介

蛋白简介

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20.

Gene names and symbols associated with ANAPC15

  • anaphase promoting complex subunit 15 (ANAPC15) 抗体
  • APC15 抗体
  • C11orf51 抗体
  • C15H11orf51 抗体

Protein level used designations for ANAPC15

anaphase-promoting complex subunit 15 , protein HSPC020 homolog

GENE ID SPECIES
25906 Homo sapiens
505356 Bos taurus
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