anti-Amyloid beta (Abeta) 抗体

Abeta encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. 再加上,我们可以发beta Amyloid 蛋白 (3)beta Amyloid 试剂盒 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
Abeta 351 P05067
Abeta 54226 P08592
Abeta 11820 P12023
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antibodies-online.cn销售最多的anti-beta Amyloid 抗体

Showing 10 out of 277 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 ELISA, ICC, IF, IHC, IHC (ff), IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - Immunofluorescent detection of beta Amyloid with MOAB-2 in the subiculim of 1-, 2- and 4- month old 5xFAD mice. Scale bar 20 um (from PMID: 22423893). Immunohistochemistry: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - IHC analysis of beta Amyloid on normal mouse brain (left) and 5xFAD mouse brain (right) using DAB with hematoxylin counterstain. The MOAB-2 antibody was used at 1:20 on normal mouse brain and at 1:400 on 5xFAD mouse brain. 0.1 mL Log in to see 7至9个工作日
$514.63
详细
非结合性 IHC, ELISA, WB 100 μg Log in to see 1至2个工作日
$389.00
详细
Cow 非结合性 WB Western blot analysis of Beta Amyloid expression in HEK293T (A), Hela (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
小鸡 非结合性 IHC, WB Immunohistochemical analysis of Beta Amyloid (pT743) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Beta Amyloid (pT743) expression in MCF7 colchicine-treated (A), mouse liver (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$575.00
详细
小鼠 山羊 非结合性 ELISA, WB Western Blot: beta Amyloid Antibody [NBP1-97755] - (0.03ug/ml) Analysis of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$485.88
详细
非结合性 ELISA, IHC, IHC (p), WB Immunohistochemistry: beta Amyloid Antibody [NBP2-25093] - Analysis of APP in human brain tissue with APP antibody at 2.5 ug/ml. Immunohistochemistry-Paraffin: beta Amyloid Antibody [NBP2-25093] - Human brain (Alzheimer's disease) tissue with APP antibody at 10 ug/mL. 0.1 mg Log in to see 8至11个工作日
$485.88
详细
Cow 非结合性 ELISA, ICC, IF, IHC, Act (ligand), WB Western Blot: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Lane 1-10: beta Amyloid pyro E3 peptide. Load: 1 ug per lane 1-2, 0.2 ug per lane 3-4, 0.05 ug per lane 5-6, 0.01 ug per lane 7-8, 0.005 ug per lane 9-10. Primary antibody: Beta Amyloid pyro E3 antibody at 0.5 ug/mL for overnight at 4C. Secondary antibody: IRDye800 rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4C. Predicted/Observed size: 86.9 kDa for beta Amyloid pyro E3 peptide. Cross reactivity with Beta Amyloid 3 peptide is >1000 fold below pyrE3 reactivity and contains no reactivity towards the Beta Amyloid 42 A beta peptide (data not shown). Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE3Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44048 antibody. 0.05 mg Log in to see 7至9个工作日
$585.06
详细
非结合性 WB Western blot analysis of Beta Amyloid expression in mouse kidney (A), mouse heart (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 EIA, IF, IHC (p), WB 0.1 mg Log in to see 6至8个工作日
$533.50
详细
Fruit Fly 非结合性 ELISA, ICC, IF, IHC, Act (ligand), WB Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - beta-amyloid (pyroglu11) NBP1-44070 in red (left) co-labeled with 6E10 in green (middle) and merge (right). Image from verified customer review. Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE11Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44070 antibody. 0.05 mg Log in to see 7至9个工作日
$585.06
详细

通过反应活性、应用领域、克隆类型和共轭标记 Abeta 抗体

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引用最多的anti-beta Amyloid 抗体

  1. Human Monoclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284085 : Youmans, Tai, Kanekiyo, Stine, Michon, Nwabuisi-Heath, Manelli, Fu, Riordan, Eimer, Binder, Bu, Yu, Hartley, LaDu: Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. in Molecular neurodegeneration 2012 (PubMed)
    Show all 10 Pubmed References

  2. Cow (Bovine) Polyclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284076 : He, Barrow: The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta. in Biochemistry 1999 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal beta Amyloid Primary Antibody for ELISA, IF - ABIN5508784 : Markoutsa, Papadia, Clemente, Flores, Antimisiaris: Anti-Aβ-MAb and dually decorated nanoliposomes: effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012 (PubMed)
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  4. Human beta Amyloid Primary Antibody for ELISA (Capture), IF - ABIN1110165 : Levites, Jansen, Smithson, Dakin, Holloway, Das, Golde et al.: Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor ... in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 3 Pubmed References

  5. Fruit Fly (Drosophila melanogaster) Polyclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284077 : Youssef, Florent-Béchard, Malaplate-Armand, Koziel, Bihain, Olivier, Leininger-Muller, Kriem, Oster, Pillot: N-truncated amyloid-beta oligomers induce learning impairment and neuronal apoptosis. in Neurobiology of aging 2008 (PubMed)
    Show all 3 Pubmed References

  6. Human beta Amyloid Primary Antibody for IF, IP - ABIN1110164 : Levites, Smithson, Price, Dakin, Yuan, Sierks, Kim, McGowan, Reed, Rosenberry, Das, Golde: Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 (PubMed)
    Show all 2 Pubmed References

  7. Human beta Amyloid Primary Antibody for ELISA (Capture), ELISA (Detection) - ABIN1110166 : Levites, Das, Price, Rochette, Kostura, McGowan, Murphy, Golde: Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model. in The Journal of clinical investigation 2006 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal beta Amyloid Primary Antibody for IHC (fro), IHC (p) - ABIN2477631 : Romaguera, Grimalt, Vilaplana: Eczematous and purpuric allergic contact dermatitis from boots. in Contact dermatitis 1990 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal beta Amyloid Primary Antibody for ELISA, WB - ABIN1573928 : Jia, Liu, Song, Pan, Chen, Cui, Wang: Berberine suppresses amyloid-beta-induced inflammatory response in microglia by inhibiting nuclear factor-kappaB and mitogen-activated protein kinase signalling pathways. in The Journal of pharmacy and pharmacology 2012 (PubMed)

更多抗beta Amyloid的相互作用对抗体

Human Amyloid beta (Abeta) interaction partners

  1. This review highlights the existing link between oxidative stress and Alzheimer's disease, and the consequences towards the ABETA (显示 APP 抗体) peptide and surrounding molecules in terms of oxidative damage. [review]

  2. overall results and observations regarding human serum albumin (显示 ALB 抗体), amyloid-beta, and metal ions advance our knowledge of how protein-protein interactions associated with amyloid-beta and metal ions could be linked to Alzheimer's disease pathogenesis

  3. electrostatic interactions in the center of the Abeta (显示 APP 抗体) peptide sequence play a crucial role in the three-dimensional fold of the fibrils, and by inference, fibril-induced neuronal toxicity and AD pathogenesis

  4. This study applies methodologies on the initial stages of aggregation of a hexamer of Alzheimer's amyloid beta fragment 25-35 (ABETA (显示 APP 抗体) 25-35) and finds that transitions within the hexameric aggregate are dominated by entropic barriers and speculates that especially the conformation entropy plays a major role in the formation of the fibril as a rate limiting factor.

  5. c-Abl is activated in AbetaOs exposed neurons and in Alzheimer's disease patient's brain, and the inhibition of activated c-Abl ameliorates cognitive deficits

  6. RelA (显示 NFkBP65 抗体), RelB (显示 RELB 抗体) and c-Rel (显示 NFkBP65 抗体) can be activated by Abeta1-40, all of which mediate pro-inflammatory cytokine transcription and retinal pigment epithelium damage.

  7. specific balance between the concentrations of monomeric and fibrillar alpha-synuclein determines the outcome of the Abeta42 aggregation reaction

  8. Nuclear HSP70 (显示 HSP70 抗体) leads to enhancement of vaccinia H1-related phosphatase (VHR (显示 DUSP3 抗体)) activity via protein-protein interaction rather than its molecular chaperone (显示 HSP90AA1 抗体) activity, thereby suppressing excessive ERK (显示 EPHB2 抗体) activation. Downregulation of either VRK3 or HSP70 (显示 HSP70 抗体) rendered cells vulnerable to glutamate (显示 GRIN1 抗体)-induced apoptosis.

  9. The authors show that lipoproteins including brain (apoE (显示 APOE 抗体)) and circulating (high-density lipoprotein, HDL (显示 HSD11B1 抗体)) synergize to facilitate beta-amyloid transport across bioengineered human cerebral vessels.

  10. The Network analyses identified APP (显示 APP 抗体) expression in temporal cortex in patient with late-onset Alzheimer's disease.

Mouse (Murine) Amyloid beta (Abeta) interaction partners

  1. ADAP KO mice developed glomerular pathology. ADAP KO podocytes lack cell protrusions with actin cytoskeleton forming circumferential stress fibers.

  2. Therefore, APP (显示 APP 抗体) modulates Nav1.6 (显示 SCN8A 抗体) sodium channels through a Go-coupled JNK (显示 MAPK8 抗体) pathway, which is dependent on phosphorylation of APP (显示 APP 抗体) at Thr668.

  3. These findings suggest that in the absence of CLU (显示 CLU 抗体), Abeta (显示 APP 抗体) clearance shifts to perivascular drainage pathways, resulting in fewer parenchymal plaques but more CAA because of loss of CLU (显示 CLU 抗体) chaperone activity, complicating the potential therapeutic targeting of CLU (显示 CLU 抗体) for AD.

  4. Chronic Dyrk1 (显示 DYRK1A 抗体) inhibition reversed cognitive deficits in Alzheimer's disease transgenic mice via reduction of APP (显示 APP 抗体) and phosphorylated tau pathology.

  5. The results of the present study substantiate that cGMP has a role in the endocytic pathway of APP (显示 APP 抗体) and suggest a scenario where the cyclic nucleotide enhances the production of Abeta (显示 APP 抗体) by favoring the trafficking of APP (显示 APP 抗体) from the cell cortex to the endolysosomal compartment.

  6. Study showed that the APP (显示 APP 抗体) Osaka mutation has dual effects: it causes a loss-of-function of APP (显示 APP 抗体) and gain-of-toxic-function of Abeta (显示 APP 抗体), though the latter seems to come out only after the former causes GABAergic depletion. Also present OSK-KI mice as a mouse model to replicate the hereditary form of recessive familial Alzheimer's disease.

  7. Results show that the duration of UP state, which is a key feature of cortical synaptic integration occurring predominantly during slow-wave sleep, is significantly increased in the prefrontal cortex in the absence of APP (显示 APP 抗体). This was accompanied by a specific reduction in the glutamine synthetase (显示 GLUL 抗体) and tissue GABA content and sequential upregulation in the levels of GABA-B receptor expression.

  8. results support the hypothesis that the miR (显示 MLXIP 抗体)-132/212 network, including Sirt1 (显示 SIRT1 抗体) and likely other target genes, contributes to abnormal Abeta (显示 APP 抗体) metabolism and senile plaque deposition in AD.

  9. Activation of CaMKIV (显示 CAMK4 抗体) by soluble amyloid-beta1-42 impedes trafficking of axonal vesicles and impairs activity-dependent synaptogenesis

  10. Abpp (显示 APP 抗体) /KPI(R13I) mutant mice were similarly deficient as Abpp (显示 APP 抗体) knock out mice in regulating cerebral thrombosis in experimental models of carotid artery thrombosis and intracerebral hemorrhage.

beta Amyloid (Abeta) 抗原简介

蛋白简介

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Gene names and symbols associated with anti-Amyloid beta (Abeta) 抗体

  • amyloid beta precursor protein (APP) 抗体
  • amyloid beta precursor protein (app) 抗体
  • amyloid beta precursor protein (App) 抗体
  • amyloid beta (A4) precursor protein (App) 抗体
  • aaa 抗体
  • Abeta 抗体
  • Abpp 抗体
  • ad1 抗体
  • Adap 抗体
  • Ag 抗体
  • appi 抗体
  • betaApp 抗体
  • ctfgamma 抗体
  • Cvap 抗体
  • E030013M08Rik 抗体
  • PN-II 抗体
  • pn2 抗体

Protein level used designations for anti-Amyloid beta (Abeta) 抗体

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II , amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease) , amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) , beta-amyloid precursor protein , alzheimer disease amyloid A4 protein homolog , amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) , ABPP , AG , amyloid A4 , amyloidogenic glycoprotein , appican , protease nexin II

GENE ID SPECIES
351 Homo sapiens
448208 Xenopus (Silurana) tropicalis
100427716 Macaca mulatta
54226 Rattus norvegicus
11820 Mus musculus
anti-beta Amyloid (Abeta) 抗体 精选生产商
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