anti-Amyloid beta (Abeta) 抗体

Abeta encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. 再加上,我们可以发beta Amyloid 蛋白 (3)beta Amyloid 试剂盒 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
Abeta 351 P05067
Abeta 54226 P08592
Abeta 11820 P12023
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antibodies-online.cn销售最多的anti-beta Amyloid 抗体

Showing 10 out of 261 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 ELISA, ICC, IF, IHC, IHC (ff), IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - Immunofluorescent detection of beta Amyloid with MOAB-2 in the subiculim of 1-, 2- and 4- month old 5xFAD mice. Scale bar 20 um (from PMID: 22423893). Immunohistochemistry: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - IHC analysis of beta Amyloid on normal mouse brain (left) and 5xFAD mouse brain (right) using DAB with hematoxylin counterstain. The MOAB-2 antibody was used at 1:20 on normal mouse brain and at 1:400 on 5xFAD mouse brain. 0.1 mL Log in to see 7至9个工作日
$514.63
详细
非结合性 IHC, ELISA, WB 100 μg Log in to see 7至9个工作日
$389.00
详细
Cow 非结合性 ELISA, ICC, IF, IHC, Act (ligand), WB Western Blot: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Lane 1-10: beta Amyloid pyro E3 peptide. Load: 1 ug per lane 1-2, 0.2 ug per lane 3-4, 0.05 ug per lane 5-6, 0.01 ug per lane 7-8, 0.005 ug per lane 9-10. Primary antibody: Beta Amyloid pyro E3 antibody at 0.5 ug/mL for overnight at 4C. Secondary antibody: IRDye800 rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4C. Predicted/Observed size: 86.9 kDa for beta Amyloid pyro E3 peptide. Cross reactivity with Beta Amyloid 3 peptide is >1000 fold below pyrE3 reactivity and contains no reactivity towards the Beta Amyloid 42 A beta peptide (data not shown). Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE3Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44048 antibody. 0.05 mg Log in to see 7至9个工作日
$585.06
详细
Cow 非结合性 WB Western blot analysis of Beta Amyloid expression in HEK293T (A), Hela (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
小鸡 非结合性 IHC, WB Immunohistochemical analysis of Beta Amyloid (pT743) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Beta Amyloid (pT743) expression in MCF7 colchicine-treated (A), mouse liver (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$575.00
详细
小鼠 非结合性 ELISA, IF, WB Fluorescent microscopy image (appotome) of 6 months-old APP/PS1 mouse hypocampus and somatosensory cortex. Double staining: in blue, nuclei DAPI staining. In red, Amyloid plaques. Immunofluorescence slices with the anti-amyloid beta antibody from different mouse genotypes. Wild type (WT), APP/PS1 and APP KO. In red, amyloid plaques. 100 μg Log in to see 6至7个工作日
$342.82
详细
非结合性 WB Western blot analysis of Beta Amyloid expression in mouse kidney (A), mouse heart (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 EIA, IF, IHC (p), WB 0.1 mg Log in to see 6至8个工作日
$533.50
详细
非结合性 ELISA, IHC, IHC (p), WB Immunohistochemistry: beta Amyloid Antibody [NBP2-25093] - Analysis of APP in human brain tissue with APP antibody at 2.5 ug/ml. Immunohistochemistry-Paraffin: beta Amyloid Antibody [NBP2-25093] - Human brain (Alzheimer's disease) tissue with APP antibody at 10 ug/mL. 0.1 mg Log in to see 8至11个工作日
$485.88
详细
非结合性 ICC, IF, IHC (p), IHC, WB Western Blot: beta Amyloid Antibody [NBP1-32081] - Sample(30 ug of whole cell lysate)A:Hep G2 7. 5% SDS PAGE, antibody diluted at 1:1500. 0.1 mL Log in to see 8至11个工作日
$514.63
详细

引用最多的anti-beta Amyloid 抗体

  1. Human Monoclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284085 : Youmans, Tai, Kanekiyo, Stine, Michon, Nwabuisi-Heath, Manelli, Fu, Riordan, Eimer, Binder, Bu, Yu, Hartley, LaDu: Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. in Molecular neurodegeneration 2012 (PubMed)
    Show all 10 Pubmed References

  2. Cow (Bovine) Polyclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284076 : He, Barrow: The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta. in Biochemistry 1999 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal beta Amyloid Primary Antibody for ELISA, IF - ABIN5508784 : Markoutsa, Papadia, Clemente, Flores, Antimisiaris: Anti-Aβ-MAb and dually decorated nanoliposomes: effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012 (PubMed)
    Show all 4 Pubmed References

  4. Human beta Amyloid Primary Antibody for ELISA (Capture), IF - ABIN1110165 : Levites, Jansen, Smithson, Dakin, Holloway, Das, Golde et al.: Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor ... in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 3 Pubmed References

  5. Fruit Fly (Drosophila melanogaster) Polyclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284077 : Youssef, Florent-Béchard, Malaplate-Armand, Koziel, Bihain, Olivier, Leininger-Muller, Kriem, Oster, Pillot: N-truncated amyloid-beta oligomers induce learning impairment and neuronal apoptosis. in Neurobiology of aging 2008 (PubMed)
    Show all 3 Pubmed References

  6. Human beta Amyloid Primary Antibody for IF, IP - ABIN1110164 : Levites, Smithson, Price, Dakin, Yuan, Sierks, Kim, McGowan, Reed, Rosenberry, Das, Golde: Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 (PubMed)
    Show all 2 Pubmed References

  7. Human beta Amyloid Primary Antibody for ELISA (Capture), ELISA (Detection) - ABIN1110166 : Levites, Das, Price, Rochette, Kostura, McGowan, Murphy, Golde: Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model. in The Journal of clinical investigation 2006 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal beta Amyloid Primary Antibody for IHC (fro), IHC (p) - ABIN2477631 : Romaguera, Grimalt, Vilaplana: Eczematous and purpuric allergic contact dermatitis from boots. in Contact dermatitis 1990 (PubMed)
    Show all 3 Pubmed References

  9. All Species Monoclonal beta Amyloid Primary Antibody for ELISA, WB - ABIN316413 : Irwin, Edward Wong, Kwon: Determining binding sites of polycyclic aromatic small molecule-based amyloid-beta peptide aggregation modulators using sequence-specific antibodies. in Analytical biochemistry 2014 (PubMed)

更多抗beta Amyloid的相互作用对抗体

Human Amyloid beta (Abeta) interaction partners

  1. Data show that amyloid precursor protein (APP (显示 APP 抗体)) dimerization affects its interaction with LDL receptor (显示 LDLR 抗体) related protein 1 (LRP1 (显示 LRP1 抗体)) and LDL-receptor (显示 LDLR 抗体) related protein SorLA (SorLA (显示 SORL1 抗体)), suggesting that APP (显示 APP 抗体) dimerization modulates its interplay with sorting molecules and in turn its localization and processing.

  2. overexpression of APP (显示 APP 抗体) may promote the onset of seborrhoeic keratosis and is a marker of skin ageing and UV damage.

  3. Structural and biochemical differences between the Notch (显示 NOTCH1 抗体) and the amyloid precursor protein (显示 APP 抗体) transmembrane domains.

  4. Gnetin C may thereby prevent Abeta (显示 APP 抗体) toxicity by suppressing BACE1 (显示 BACE 抗体) and enhancing MMP-14 (显示 MMP14 抗体), together with reducing both internalization and oligomerization of exogenous Abeta (显示 APP 抗体) monomers.

  5. Amyloid precursor protein (APP (显示 APP 抗体)) binds the HIV-1 Gag polyprotein, retains it in lipid rafts and blocks HIV-1 virion production and spread.

  6. ABETA(1-42) doses >5 microM (显示 APP 抗体) inhibited the growth of U87 cells compared with the 0 microM group after 24 and 48 h treatment.

  7. The mechanism involved in the interaction of HSP60-Ass conjugate with HLA-DR-DRB allele considering the fact that Ass (1-42) is highly immunogenic in human and interactions evoked highly robust T-cell response through MHC class II binding predictions.

  8. Abeta (显示 APP 抗体) fibrils start to accumulate predominantly within certain parts of the default mode network in preclinical Alzheimer's disease and already then affect brain connectivity.

  9. findings show adverse effects of one-night sleep deprivation on brain ABB and expand on prior findings of higher Abeta (显示 APP 抗体) accumulation with chronic less sleep.

  10. This review highlights the existing link between oxidative stress and Alzheimer's disease, and the consequences towards the ABETA (显示 APP 抗体) peptide and surrounding molecules in terms of oxidative damage. [review]

Mouse (Murine) Amyloid beta (Abeta) interaction partners

  1. These results support the proposition that A&beta (显示 SUCLA2 抗体); release during thrombosis serves as part of a natural defense against infection.

  2. These data suggest a novel regulatory function of juxta- and intra-membrane domains on the metabolism and function of APP (显示 APP 抗体).

  3. Inflammasome-derived cytokine IL18 (显示 IL18 抗体) suppresses amyloid-induced seizures in Alzheimer-prone mice.

  4. pharmacological inhibition of PARP-1 (显示 PARP1 抗体) reversed both particulate matter-induced Abeta (显示 APP 抗体) increase and glial activation.

  5. The concentrations of Abeta (显示 APP 抗体) (1-42) were also significantly higher in early stage Alzheimer's disease (AD) mice compared with WT mice, however, the levels were markedly lower compared with later stage AD mice, as determined by ELISA. In addition to increased levels of Abeta (显示 APP 抗体) (1-42) in mice with later stage AD, reduced astrocyte staining was observed compared with WT mice.

  6. work expands the current knowledge regarding Abeta (显示 APP 抗体) seeding and the consequences thereof and attributes microglia an important role in diminishing Abeta (显示 APP 抗体) seeding by environmental enrichment.

  7. This study demonstrated that APP (显示 APP 抗体) as a novel receptor for Slit ligand mediating axon guidance and neural circuit formation.

  8. In vivo, the NHE6 (显示 SLC9A6 抗体) knockout (NHE6 (显示 SLC9A6 抗体)(KO)) mouse model showed elevated Abeta (显示 APP 抗体) in the brain, consistent with a causal effect. Increased nuclear translocation of histone deacetylase 4 (HDAC4 (显示 HDAC5 抗体)) in ApoE4 astrocytes, compared with the nonpathogenic ApoE3 allele, suggested a mechanistic basis for transcriptional down-regulation of NHE6 (显示 SLC9A6 抗体).

  9. This commentary reviews the role of the Alzheimer amyloid peptide Abeta (显示 APP 抗体) on basal synaptic transmission, synaptic short-term plasticity, as well as short- and long-term potentiation in transgenic mice, with a special focus on N-terminal truncated Abeta4-42.

  10. ADAP KO mice developed glomerular pathology. ADAP KO podocytes lack cell protrusions with actin cytoskeleton forming circumferential stress fibers.

beta Amyloid (Abeta) 抗原简介

蛋白简介

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Gene names and symbols associated with anti-Amyloid beta (Abeta) 抗体

  • amyloid beta precursor protein (APP) 抗体
  • amyloid beta precursor protein (app) 抗体
  • amyloid beta precursor protein (App) 抗体
  • amyloid beta (A4) precursor protein (App) 抗体
  • aaa 抗体
  • Abeta 抗体
  • Abpp 抗体
  • ad1 抗体
  • Adap 抗体
  • Ag 抗体
  • appi 抗体
  • betaApp 抗体
  • ctfgamma 抗体
  • Cvap 抗体
  • E030013M08Rik 抗体
  • PN-II 抗体
  • pn2 抗体

Protein level used designations for anti-Amyloid beta (Abeta) 抗体

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II , amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease) , amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) , beta-amyloid precursor protein , alzheimer disease amyloid A4 protein homolog , amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) , ABPP , AG , amyloid A4 , amyloidogenic glycoprotein , appican , protease nexin II

GENE ID SPECIES
351 Homo sapiens
448208 Xenopus (Silurana) tropicalis
100427716 Macaca mulatta
54226 Rattus norvegicus
11820 Mus musculus
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