anti-Amyloid beta (Abeta) 抗体

Abeta encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. 再加上,我们可以发beta Amyloid 试剂盒 (12)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
Abeta 351 P05067
Abeta 54226 P08592
Abeta 11820 P12023
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • 在线下订单
  • orders@antibodies-online.cn

antibodies-online.cn销售最多的anti-beta Amyloid 抗体

Showing 10 out of 276 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IHC, ELISA, WB 25 μL Log in to see 1至2个工作日
$139.00
详细
小鼠 非结合性 IHC, ELISA Abeta oligomer-specific antibody was adsorbed to Nunc-Immuno MaxiSorp plates (Nunc, Roskilde, Denmark) at 2 ug/ml in PBS. 1 ml of a 10 uM Aβ(1-42) sample containing a small fraction of Aβ-oligomers was separated using a superdex G75 (10/30) column. Aβ-fractions collected from the SEC were allowed to bind to OMAB plates for 20 minutes at 0°C. All fractions were analyzed and bound Aβ was detected using a polyclonal rabbit anti-Aβ antibody (ABIN249343) at a 1:1000 dilution followed by an anti-rabbit HRP-conjugated secondary antibody at a 1:5000 dilution (GE healthcare). ECBlue (Medicago, Uppsala, Sweden) was used as a substrate for HRP and the signal was detected by measuring the absorbance at 450 nm. Blocking solution and antibody-dilutions were made with 5% Non-fat dry milk in PBST and all washes were performed with PBS containing 0.1% Tween-20 (PBST). 10 µm of coronal sections from fresh-frozen transgenic mouse brain mutant (A) and wild type (B). Post-fixation in 4% formaldehyde solution, 5 min. OMAB antibody diluted 1:500, incubation at 4ºC ON. Mouse on mouse HRP-Polymer kit according to company instructions. Biocare Medical: BC-MM510 (Histolab) DAB substrate kit for peroxidase. Vector Laboratories: SK-4100 (ImmunKemi) Counterstained with Mayers HTX. 50 μg Log in to see 6至8个工作日
$766.59
详细
小鸡 非结合性 IHC, WB Immunohistochemical analysis of Beta Amyloid (pT743) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Beta Amyloid (pT743) expression in MCF7 colchicine-treated (A), mouse liver (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$575.00
详细
小鼠 非结合性 ELISA, ICC, IF, IHC, IHC (ff), IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - Immunofluorescent detection of beta Amyloid with MOAB-2 in the subiculim of 1-, 2- and 4- month old 5xFAD mice. Scale bar 20 um (from PMID: 22423893). Immunohistochemistry: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - IHC analysis of beta Amyloid on normal mouse brain (left) and 5xFAD mouse brain (right) using DAB with hematoxylin counterstain. The MOAB-2 antibody was used at 1:20 on normal mouse brain and at 1:400 on 5xFAD mouse brain. 0.1 mL Log in to see 7至9个工作日
$514.63
详细
非结合性 ELISA, IHC, IHC (p), WB Immunohistochemistry: beta Amyloid Antibody [NBP2-25093] - Analysis of APP in human brain tissue with APP antibody at 2.5 ug/ml. Immunohistochemistry-Paraffin: beta Amyloid Antibody [NBP2-25093] - Human brain (Alzheimer's disease) tissue with APP antibody at 10 ug/mL. 0.1 mg Log in to see 8至11个工作日
$485.88
详细
小鼠 山羊 非结合性 ELISA, WB Western Blot: beta Amyloid Antibody [NBP1-97755] - (0.03ug/ml) Analysis of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$485.88
详细
Cow 非结合性 ELISA, ICC, IF, IHC, Act (ligand), WB Western Blot: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Lane 1-10: beta Amyloid pyro E3 peptide. Load: 1 ug per lane 1-2, 0.2 ug per lane 3-4, 0.05 ug per lane 5-6, 0.01 ug per lane 7-8, 0.005 ug per lane 9-10. Primary antibody: Beta Amyloid pyro E3 antibody at 0.5 ug/mL for overnight at 4C. Secondary antibody: IRDye800 rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4C. Predicted/Observed size: 86.9 kDa for beta Amyloid pyro E3 peptide. Cross reactivity with Beta Amyloid 3 peptide is >1000 fold below pyrE3 reactivity and contains no reactivity towards the Beta Amyloid 42 A beta peptide (data not shown). Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE3Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44048 antibody. 0.05 mg Log in to see 7至9个工作日
$585.06
详细
Fruit Fly 非结合性 ELISA, ICC, IF, IHC, Act (ligand), WB Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - beta-amyloid (pyroglu11) NBP1-44070 in red (left) co-labeled with 6E10 in green (middle) and merge (right). Image from verified customer review. Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE11Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44070 antibody. 0.05 mg Log in to see 7至9个工作日
$585.06
详细
非结合性 EIA, IF, IHC (p), WB 0.1 mg Log in to see 6至8个工作日
$533.50
详细
非结合性 ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using Amyloid-beta Polyclonal Antibody. 100 μL Log in to see 16 Days
$181.73
详细

通过反应活性、应用领域、克隆类型和共轭标记 Abeta 抗体

特性 应用范围 宿主 克隆类型 标记
Human , , , ,
, , ,
,
, , , , , , , , , , , , , , , , , , ,
Rat (Rattus) , ,
, ,
,
, , , , , , , , , , , , ,
Mouse (Murine) , , ,
, , ,
,
, , , , , , , , , , , , ,

引用最多的anti-beta Amyloid 抗体

  1. Human Monoclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284085 : Youmans, Tai, Kanekiyo, Stine, Michon, Nwabuisi-Heath, Manelli, Fu, Riordan, Eimer, Binder, Bu, Yu, Hartley, LaDu: Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. in Molecular neurodegeneration 2012 (PubMed)
    Show all 8 Pubmed References

  2. Cow (Bovine) Polyclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284076 : He, Barrow: The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta. in Biochemistry 1999 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal beta Amyloid Primary Antibody for ELISA, IF - ABIN5508784 : Markoutsa, Papadia, Clemente, Flores, Antimisiaris: Anti-Aβ-MAb and dually decorated nanoliposomes: effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012 (PubMed)
    Show all 4 Pubmed References

  4. Fruit Fly (Drosophila melanogaster) Polyclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284077 : Youssef, Florent-Béchard, Malaplate-Armand, Koziel, Bihain, Olivier, Leininger-Muller, Kriem, Oster, Pillot: N-truncated amyloid-beta oligomers induce learning impairment and neuronal apoptosis. in Neurobiology of aging 2008 (PubMed)
    Show all 3 Pubmed References

  5. Human beta Amyloid Primary Antibody for ELISA (Capture), IF - ABIN1110165 : Levites, Jansen, Smithson, Dakin, Holloway, Das, Golde et al.: Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor ... in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 3 Pubmed References

  6. Human beta Amyloid Primary Antibody for IF, IP - ABIN1110164 : Levites, Smithson, Price, Dakin, Yuan, Sierks, Kim, McGowan, Reed, Rosenberry, Das, Golde: Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 (PubMed)
    Show all 2 Pubmed References

  7. Human beta Amyloid Primary Antibody for ELISA (Capture), ELISA (Detection) - ABIN1110166 : Levites, Das, Price, Rochette, Kostura, McGowan, Murphy, Golde: Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model. in The Journal of clinical investigation 2006 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal beta Amyloid Primary Antibody for IHC (fro), IHC (p) - ABIN2477631 : Romaguera, Grimalt, Vilaplana: Eczematous and purpuric allergic contact dermatitis from boots. in Contact dermatitis 1990 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal beta Amyloid Primary Antibody for ELISA, IHC - ABIN4284094 : Stieren, El Ayadi, Xiao, Siller, Landsverk, Oberhauser, Barral, Boehning: Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein. in The Journal of biological chemistry 2011 (PubMed)

更多抗beta Amyloid的相互作用对抗体

Human Amyloid beta (Abeta) interaction partners

  1. Data, including data from studies using cadaver tissue, suggest that matriptase (显示 ST14 抗体) and matriptase (显示 ST14 抗体) mRNA are expressed in several regions of the brain with an enrichment in neurons; higher levels of matriptase (显示 ST14 抗体) RNA are expressed in young individuals as compared to older individuals; matriptase (显示 ST14 抗体) cleaves amyloid beta precursor protein at a specific arginine residue (Arg-102).

  2. Overexpression of SNX7 (显示 SNX7 抗体) in HEK293T cells reduces the levels of secreted Abeta (显示 APP 抗体) and beta-cleaved N-terminal APP (显示 APP 抗体) fragments (sAPPbeta). Moreover, SNX7 (显示 SNX7 抗体) overexpression caused a significant reduction of the steady-state levels of APP (显示 APP 抗体) as well as of the cell surface APP (显示 APP 抗体) levels.

  3. modulation of proteostasis is a distinct biological function of sAPPalpha and does not require surface-bound holo-APP (显示 APP 抗体).

  4. elevated levels of plasma homocysteine /homocysteine thiolactone contribute to AD pathology via the Abeta (显示 APP 抗体)-fibrin(ogen) interaction

  5. Overexpression of human APP (显示 APP 抗体) in mice reduce cortical free cholesterol under normal diet and HFD.

  6. The authors show that APP (显示 APP 抗体) can physically interact with KCC2 (显示 SLC12A5 抗体), a neuron-specific K(+)-Cl(-) cotransporter (显示 SLC12A4 抗体) that is essential for Cl(-) homeostasis and fast GABAergic inhibition.

  7. beta-amyloid interacts with fibrinogen and factor XII (显示 F12 抗体). These interactions can lead to increased clotting, abnormal clot (显示 TXNDC17 抗体) formation, persistent fibrin deposition, and generation of proinflammatory molecules.

  8. Abeta (显示 APP 抗体) activates FXII (显示 F12 抗体), resulting in FXI (显示 F11 抗体) activation and thrombin (显示 F2 抗体) generation in human plasma, thereby establishing Abeta (显示 APP 抗体) as a possible driver of prothrombotic states

  9. Data suggest that aggregates of amyloid beta(1-40) induce excessive generation of reactive oxygen species, MAPK (显示 MAPK1 抗体)/NFkappaB (显示 NFKB1 抗体) signaling activation, and NLRP3 (显示 NLRP3 抗体) inflammasome activation in retinal pigment epithelial cells mimicking changes seen in age-related macular degeneration; this mechanism is dependent on NADPH oxidase (显示 NOX1 抗体).

  10. These results demonstrate a stage-dependent plasma Abeta (显示 APP 抗体) increase that is augmented by loss of glomerulotubular integrity, low body weight, and inflammation, demonstrating a multifaceted role of renal dysfunction in Abeta (显示 APP 抗体) retention.

Mouse (Murine) Amyloid beta (Abeta) interaction partners

  1. long term survival and amyloid protein (显示 IAPP 抗体) levels are modified by positive and negative early life experiences in a mouse model of Alzheimer's disease

  2. the synaptic localization of APP (显示 APP 抗体), ADAM10 (显示 ADAM10 抗体), and BACE1 (显示 BACE 抗体) in the mouse cerebral cortex, was examined.

  3. Taken together, these results suggest that apoE (显示 APOE 抗体)-containing discoidal HDLs (显示 CSF1R 抗体) do not require LCAT (显示 LCAT 抗体)-dependent maturation to mediate efficient Abeta (显示 APP 抗体) clearance

  4. APP (显示 APP 抗体) knockout mice have shorter dendritic arbors in the hippocampus.

  5. This study demonstrates the neuroprotective effect of TSG (显示 TWSG1 抗体) on APP (显示 APP 抗体) expression, suggesting that TSG (显示 TWSG1 抗体) may be beneficial for AD prevention and treatment.

  6. SNX15 (显示 SNX15 抗体) regulates the recycling of APP (显示 APP 抗体) to cell surface and, thus, its processing for Abeta (显示 APP 抗体) generation.

  7. Immunohistochemical analysis confirmed increased amount of NOS1 (显示 NOS1 抗体) protein in neuronal somata and processes in the perilesional cortex in APP (显示 APP 抗体)/PS1 (显示 PSEN1 抗体)-severe traumatic brain injury(TBI) mice compared to APP (显示 APP 抗体)/PS1 (显示 PSEN1 抗体)-sham (p < 0.05) or Wt-sTBI mice (p < 0.01).

  8. Combining a murine APP (显示 APP 抗体)-deficient and a human APP (显示 APP 抗体)-transgenic strain, we were able to analyse the progression of the cortical amyloidosis independent of the murine variant. The lack of endogenous mAPP (显示 XPNPEP2 抗体) resulted in accelerated deposition and, thus, increased number of senile plaques and higher levels of aggregated hAbeta.

  9. our findings indicate that sortilin (显示 SORT1 抗体) is a beneficial protein for the reduction of amyloid pathology in APP (显示 APP 抗体)/PS1 (显示 PSEN1 抗体) mice by promoting APP (显示 APP 抗体) degradation

  10. APP levels then decrease progressively as a function of age in close relationship with the gradual normalization of FMRP and hnRNP C levels.

beta Amyloid (Abeta) 抗原简介

蛋白简介

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Gene names and symbols associated with anti-Amyloid beta (Abeta) 抗体

  • amyloid beta precursor protein (APP) 抗体
  • amyloid beta precursor protein (app) 抗体
  • amyloid beta precursor protein (App) 抗体
  • amyloid beta (A4) precursor protein (App) 抗体
  • aaa 抗体
  • Abeta 抗体
  • Abpp 抗体
  • ad1 抗体
  • Adap 抗体
  • Ag 抗体
  • appi 抗体
  • betaApp 抗体
  • ctfgamma 抗体
  • Cvap 抗体
  • E030013M08Rik 抗体
  • PN-II 抗体
  • pn2 抗体

Protein level used designations for anti-Amyloid beta (Abeta) 抗体

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II , amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease) , amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) , beta-amyloid precursor protein , alzheimer disease amyloid A4 protein homolog , amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) , ABPP , AG , amyloid A4 , amyloidogenic glycoprotein , appican , protease nexin II

GENE ID SPECIES
351 Homo sapiens
448208 Xenopus (Silurana) tropicalis
100427716 Macaca mulatta
54226 Rattus norvegicus
11820 Mus musculus
anti-beta Amyloid (Abeta) 抗体 精选生产商
您还需要查找其他产品吗?