anti-Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) 抗体

The protein encoded by ACSL4 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. 再加上,我们可以发ACSL4 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ACSL4 2182 O60488
ACSL4 50790 Q9QUJ7
ACSL4 113976 O35547
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Showing 10 out of 105 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IF, IHC (p), WB The anti-FACL4 Pab (ABIN389113) is used in Western blot to detect FACL4 in RKO cell lysate (human colon cancer) treated with 10% FCS for 24 hrs. Data is kindly provided by Drs. M.G. Sciulli and P. Patrignani from the University of Chieti (Italy). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10至11个工作日
Cow 非结合性 WB WB Suggested Anti-ACSL4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Hela cell lysate 100 μL Log in to see 2至3个工作日
Cow 非结合性 WB Host:  Rabbit  Target Name:  Acsl4  Sample Type:  Mouse Thymus lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2至3个工作日
山羊 非结合性 ELISA, IHC, WB Antibody (0.1µg/ml) staining of HepG2 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6至7个工作日
非结合性 ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: FACL4 Antibody [NBP2-16401] - Paraffin-embedded mouse lymph node. FACL4 antibody [C3], C-term dilution: 1:500. Immunohistochemistry-Paraffin: FACL4 Antibody [NBP2-16401] - Immunohistochemical analysis of paraffin-embedded HBL435 xenograft, using antibody at 1:500 dilution. 0.1 mL Log in to see 8至11个工作日
非结合性 ICC, IF, IP, IHC (p), WB ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using FACL4, antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with  (Red) at 1:2000. WB Image Sample (30 ug of whole cell lysate) A: Hela B: NT2D1 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 3至4个工作日
非结合性 WB ACSL4 Antibody (N-term) (ABIN658327) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the ACSL4 antibody detected the ACSL4 protein (arrow). 400 μL Log in to see 10至11个工作日
Bat 山羊 非结合性 ELISA, IHC, IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11至14个工作日
Bat 非结合性 IHC, IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-ACSL4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Ot ... 50 μg Log in to see 11至14个工作日
非结合性 EIA, IF, IHC (p), WB   0.4 mL Log in to see 8至11个工作日

引用最多的anti-ACSL4 抗体

  1. Human Polyclonal ACSL4 Primary Antibody for IF, IHC (p) - ABIN389113 : Rodriguez, Bhat, Meloni, Ladd, Leslie, Doyne, Renieri, Dupont, Stevenson, Schwartz, Srivastava: Intellectual disability, midface hypoplasia, facial hypotonia, and Alport syndrome are associated with a deletion in Xq22.3. in American journal of medical genetics. Part A 2010 (PubMed)
    Show all 11 Pubmed References

  2. Human Polyclonal ACSL4 Primary Antibody for IHC (p), ELISA - ABIN543466 : Tsai, Sheen-Chen, Huang, Chen, Chi, Ko, Lee, Liang, Hsu, Huang, Chen, Huang, Rau, Tang: An evaluation of fatty acid-CoA ligase 4 in breast cancer. in Anticancer research 2014 (PubMed)

  3. Human Polyclonal ACSL4 Primary Antibody for ELISA, WB - ABIN268614 : Piccini, Vitelli, Bruttini, Pober, Jonsson, Villanova, Zollo, Borsani, Ballabio, Renieri: FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation. in Genomics 1998 (PubMed)


Human Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) interaction partners

  1. ACSL3 distribution closely overlapped with proteins involved in trafficking from the trans-Golgi network and endosomes. In contrast, the ACSL4 localisation pattern more closely followed that of calnexin which is an endoplasmic reticulum resident chaperone.

  2. The regulatory network among peroxisomal ABCD2:ACSL4:VLCFA serves as a novel regulator of cartilage homeostasis, and these data may provide novel insights into the role of peroxisomal fatty acid metabolism in pathogenesis of human osteoarthritis (OA).

  3. Study demonstrated that ACSL4 was overexpressed in HCC.

  4. These results suggest that ACSL1, ACSL4 and ACSL5 expression is regulated by ER signaling pathways and ACSL5 is a potential novel biomarker for predicting prognosis of breast cancer patients.

  5. studies have identified a novel substrate-induced posttranslational regulatory mechanism by which AA downregulates ACSL4 protein expression in hepatic cells.

  6. Data show that ELOVL7, SOCS3, ACSL4 and CLU were upregulated while PRKAR1A and ABCG1 were downregulated in the phlegm-dampness group.

  7. ACSL4 is not only a sensitive monitor of ferroptosis, but also an important contributor of ferroptosis.

  8. ACLS4 and ACLS3 have roles in insulin secretion

  9. Silencing of ACSL4 eliminated the 17beta-estradiol-induced increase in AA and EPA uptake.

  10. ACSL4 plays a tumor-suppressive role in gastric cancer.

  11. Suggest role for ACSL4 expression in development of castration-resistant prostate cancer.

  12. we demonstrate that ACSL4 can be considered a novel activator of the mTOR pathway

  13. In vitro analysis showed that a recombinant COX-2 enzyme more effectively metabolized 5(S)-HETE to 5-11-diHETE compared to COX-1 enzyme.

  14. Upregulation of ACSL4 is responsible for the increase in triacylglycerol species containing long polyunsaturated fatty acids during activation of hepatic stellate cells.

  15. Report PPARdelta-mediated regulatory mechanism for ACSL4 expression in liver tissue and cultured hepatic cells.

  16. ACSL4 can serve as both a biomarker for, and mediator of, an aggressive breast cancer phenotype.

  17. This study found no significant relationship between FACL4 and cognitive function.

  18. conclude that in our model system exogenous fatty acids are channeled preferentially towards phosphatidylinositol by ACSL4 overexpression

  19. MiR-205 down-regulates ACSL4 through targeting its 3'UTR in hepatoma cells.

  20. The functional interaction between Acyl-CoA synthetase 4, 5-lipooxygenase and cyclooxygenase-2 controls tumor growth.

Pig (Porcine) Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) interaction partners

  1. Results indicate that fatty acid binding protein H-FABP and CoA ligase 4 ACSL4 genes might serve as markers to improve fat (IMF) content in the breeding system.

  2. ACSL4 Single Nucleotide Polymorphism G2645A is associated with several meat quality traits.

  3. mapping to the X chromosome

  4. Polymorphisms within the ACSL4 gene are associated with growth and meat quality.

Arabidopsis thaliana Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) interaction partners

  1. The analyses of mutant lines revealed strongly overlapping functions of LACS4 and LACS9 in lipid trafficking from the endoplasmic reticulum to the plastid.

  2. The combined inactivation of LACS1 and LACS4 in Arabidopsis resulted in conditional pollen sterility and impaired wax biosynthesis.

ACSL4 抗原简介


The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.

Gene names and symbols associated with ACSL4

  • acyl-CoA synthetase long chain family member 4a (acsl4a) 抗体
  • acyl-CoA synthetase long-chain family member 4 (ACSL4) 抗体
  • acyl-CoA synthetase long chain family member 4 (ACSL4) 抗体
  • AcsL4 (acsL4) 抗体
  • acyl-CoA synthetase long chain family member 3 (acsl3) 抗体
  • Long-chain-fatty-acid--CoA ligase 4 (acsl4) 抗体
  • acyl-CoA synthetase long-chain family member 4 (Acsl4) 抗体
  • acyl-CoA synthetase long-chain family member 4 S homeolog (acsl4.S) 抗体
  • AMP-dependent synthetase and ligase family protein (LACS4) 抗体
  • 9430020A05Rik 抗体
  • acs4 抗体
  • acsl3 抗体
  • ACSL4 抗体
  • AU018108 抗体
  • facl4 抗体
  • lacs4 抗体
  • long-chain acyl-CoA synthetase 4 抗体
  • mrx63 抗体
  • mrx68 抗体
  • T32A16.20 抗体
  • T32A16_20 抗体
  • zgc:66186 抗体

Protein level used designations for ACSL4

acyl-CoA synthetase long-chain family member 4 , long-chain-fatty-acid--CoA ligase 4 , AcsL4 , Long-chain-fatty-acid--CoA ligase 4 , long-chain-fatty-acid--CoA ligase 4-like , LACS 4 , acyl-CoA synthetase 4 , fatty-acid-Coenzyme A ligase, long-chain 4 , lignoceroyl-CoA synthase , long-chain acyl-CoA synthetase 4 , long-chain fatty-acid-Coenzyme A ligase 4 , fatty acid-Coenzyme A ligase, long chain 4 , mACS4 , fatty acid Coenzyme A ligase, long chain 4 , fatty acid-Coenzyme A ligase long chain 4 , acyl-CoA synthetase long-chain family member 3

393622 Danio rerio
422345 Gallus gallus
704908 Macaca mulatta
740279 Pan troglodytes
7502699 Desulfobacterium autotrophicum HRM2
100013435 Monodelphis domestica
100036652 Xenopus (Silurana) tropicalis
100073630 Ornithorhynchus anatinus
100342485 Oryctolagus cuniculus
100380405 Salmo salar
100462347 Pongo abelii
100469615 Ailuropoda melanoleuca
100539925 Meleagris gallopavo
2182 Homo sapiens
536628 Bos taurus
50790 Mus musculus
113976 Rattus norvegicus
481018 Canis lupus familiaris
448980 Sus scrofa
100174803 Xenopus laevis
828484 Arabidopsis thaliana
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