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The protein encoded by ACSL4 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. 再加上，我们可以发ACSL4 蛋白 (9) 和 和数多这个蛋白质的别的产品。
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Human Polyclonal ACSL4 Primary Antibody for IF, IHC (p) - ABIN389113
Rodriguez, Bhat, Meloni, Ladd, Leslie, Doyne, Renieri, Dupont, Stevenson, Schwartz, Srivastava: Intellectual disability, midface hypoplasia, facial hypotonia, and Alport syndrome are associated with a deletion in Xq22.3. in American journal of medical genetics. Part A 2010
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Human Polyclonal ACSL4 Primary Antibody for ELISA, WB - ABIN268614
Piccini, Vitelli, Bruttini, Pober, Jonsson, Villanova, Zollo, Borsani, Ballabio, Renieri: FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation. in Genomics 1998
Study demonstrated that ACSL4 was overexpressed in HCC (显示 FAM126A 抗体).
These results suggest that ACSL1 (显示 Acsl1 抗体), ACSL4 and ACSL5 (显示 ACSL5 抗体) expression is regulated by ER signaling pathways and ACSL5 (显示 ACSL5 抗体) is a potential novel biomarker for predicting prognosis of breast cancer patients.
studies have identified a novel substrate-induced posttranslational regulatory mechanism by which AA downregulates ACSL4 protein expression in hepatic cells.
Data show that ELOVL7 (显示 ELOVL7 抗体), SOCS3 (显示 SOCS3 抗体), ACSL4 and CLU (显示 CLU 抗体) were upregulated while PRKAR1A (显示 PRKAR1A 抗体) and ABCG1 (显示 ABCG1 抗体) were downregulated in the phlegm-dampness group.
ACSL4 is not only a sensitive monitor of ferroptosis, but also an important contributor of ferroptosis.
ACLS4 and ACLS3 have roles in insulin (显示 INS 抗体) secretion
Silencing of ACSL4 eliminated the 17beta-estradiol-induced increase in AA and EPA uptake.
ACSL4 plays a tumor-suppressive role in gastric cancer.
Suggest role for ACSL4 expression in development of castration-resistant prostate cancer.
we demonstrate that ACSL4 can be considered a novel activator of the mTOR (显示 FRAP1 抗体) pathway
Report PPARdelta (显示 PPARD 抗体)-mediated regulatory mechanism for ACSL4 expression in liver tissue and cultured hepatic cells.
Sequence analysis of a 1.5-kb fragment of the Acsl4 promoter revealed the absence of a TATA box and the presence of many putative binding sites for transcription factors including Sp1 (显示 SP1 抗体) and CREB (显示 CREB1 抗体).
Acsl4 is a phosphoprotein whose phosphorylation is hormone-dependent.
These results indicate that the ACS4 protein specifically expressed in brain plays an important role in arachidonate metabolism and neuronal differentiation in the brain.
the involvement of SHP2 (显示 PTPN11 抗体) activity in the regulation of the expression of the fatty acid-metabolizing enzyme ACSL4
Results indicate that fatty acid binding protein H-FABP (显示 FABP3 抗体) and CoA ligase 4 ACSL4 genes might serve as markers to improve fat (IMF (显示 MDFI 抗体)) content in the breeding system.
ACSL4 Single Nucleotide Polymorphism G2645A is associated with several meat quality traits.
Polymorphisms within the ACSL4 gene are associated with growth and meat quality.
The analyses of mutant lines revealed strongly overlapping functions of LACS4 and LACS9 in lipid trafficking from the endoplasmic reticulum to the plastid.
The combined inactivation of LACS1 (显示 Acsl1 抗体) and LACS4 in Arabidopsis resulted in conditional pollen sterility and impaired wax biosynthesis.
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
acyl-CoA synthetase long-chain family member 4
, long-chain-fatty-acid--CoA ligase 4
, Long-chain-fatty-acid--CoA ligase 4
, long-chain-fatty-acid--CoA ligase 4-like
, LACS 4
, acyl-CoA synthetase 4
, fatty-acid-Coenzyme A ligase, long-chain 4
, lignoceroyl-CoA synthase
, long-chain acyl-CoA synthetase 4
, long-chain fatty-acid-Coenzyme A ligase 4
, fatty acid-Coenzyme A ligase, long chain 4
, fatty acid Coenzyme A ligase, long chain 4
, fatty acid-Coenzyme A ligase long chain 4
, acyl-CoA synthetase long-chain family member 3