ABCA4 抗体
(ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ABCA4 抗体 (AA 2250-2263) | 人, 小鼠 | 山羊 Polyclonal |
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| ABCA4 抗体 | 人 | 兔 Polyclonal |
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| ABCA4 抗体 (AA 1398-1727) | 人 | 兔 Polyclonal |
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| ABCA4 抗体 (AA 2174-2273) | 人 | 小鼠 Polyclonal |
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| ABCA4 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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| ABCA4 抗体 (AA 630-710) | 人, 小鼠 | 兔 Polyclonal |
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| ABCA4 抗体 (AA 1893-1906) | 人, 猴 | 兔 Polyclonal |
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| ABCA4 抗体 (AA 1892-1903) | 小鼠, 大鼠, Bat, 豚鼠, 兔 | 兔 Polyclonal |
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| ABCA4 抗体 (AA 110-300) | 人 | 兔 Polyclonal |
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| ABCA4 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA4 抗体 (AA 630-710) | 人, 小鼠 | 兔 Polyclonal |
|
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| ABCA4 抗体 (HRP) | 人 | 兔 Polyclonal |
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| ABCA4 抗体 (AA 1336-49) | 人 | 山羊 Polyclonal |
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| ABCA4 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Rockland Original | ABCA4 抗体 | Cow | 小鼠 Monoclonal |
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| ABCA4 抗体 (Center) | 人, 小鼠, 大鼠, 猴, 犬 | 兔 Polyclonal |
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| ABCA4 抗体 (AA 1890-1927) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA4 抗体 (C-Term) (Cy3) | 小鼠 | 兔 Polyclonal |
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| ABCA4 抗体 (C-Term) (Cy3) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA4 抗体 (C-Term) (Cy3) | 人 | 兔 Polyclonal |
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Primary Antibody
- IF (Immunofluorescence: 有验证图片)
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
3 references - 质量等级
- Verified
- 适用
- 人, 小鼠
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2250-2263
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1398-1727
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 2174-2273
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 630-710
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1893-1906
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 小鼠, 大鼠, Bat, 豚鼠, 兔
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1892-1903
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 110-300
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 630-710
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
Primary Antibody
- ELISA (ELISA: 所列应用)
- 质量等级
- Recent
- 适用
- 人
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1336-49
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Rockland Original
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, 猴, 犬
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1890-1927
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Latest Publications for our ABCA4 抗体
: "Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution." in: Cell, Vol. 182, Issue 6, pp. 1623-1640.e34, (2021) (PubMed).
: "Assessment of AAV Dual Vector Safety in theAbca4-/- Mouse Model of Stargardt Disease." in: Translational vision science & technology, Vol. 9, Issue 7, pp. 20, (2020) (PubMed).
: "An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease." in: PLoS genetics, Vol. 15, Issue 3, pp. e1007873, (2019) (PubMed).
: "An AAV Dual Vector Strategy Ameliorates the Stargardt Phenotype in Adult Abca4-/- Mice." in: Human gene therapy, Vol. 30, Issue 5, pp. 590-600, (2019) (PubMed).
: "Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 47, pp. E11120-E11127, (2019) (PubMed).
: "Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice." in: The Journal of clinical investigation, Vol. 118, Issue 5, pp. 1955-64, (2008) (PubMed).
: "Homozygous null mutations in the ABCA4 gene in two families with autosomal recessive retinal dystrophy." in: American journal of ophthalmology, Vol. 141, Issue 5, pp. 906-13, (2006) (PubMed).
: "ABCA4 mutations causing mislocalization are found frequently in patients with severe retinal dystrophies." in: Human molecular genetics, Vol. 14, Issue 19, pp. 2769-78, (2005) (PubMed).
: "The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily." in: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10303-10, (1997) (PubMed).
: "Assessment of AAV Dual Vector Safety in theAbca4-/- Mouse Model of Stargardt Disease." in: Translational vision science & technology, Vol. 9, Issue 7, pp. 20, (2020) (PubMed).
: "An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease." in: PLoS genetics, Vol. 15, Issue 3, pp. e1007873, (2019) (PubMed).
: "An AAV Dual Vector Strategy Ameliorates the Stargardt Phenotype in Adult Abca4-/- Mice." in: Human gene therapy, Vol. 30, Issue 5, pp. 590-600, (2019) (PubMed).
: "Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 47, pp. E11120-E11127, (2019) (PubMed).
: "Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice." in: The Journal of clinical investigation, Vol. 118, Issue 5, pp. 1955-64, (2008) (PubMed).
: "Homozygous null mutations in the ABCA4 gene in two families with autosomal recessive retinal dystrophy." in: American journal of ophthalmology, Vol. 141, Issue 5, pp. 906-13, (2006) (PubMed).
: "ABCA4 mutations causing mislocalization are found frequently in patients with severe retinal dystrophies." in: Human molecular genetics, Vol. 14, Issue 19, pp. 2769-78, (2005) (PubMed).
: "The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily." in: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10303-10, (1997) (PubMed).
Aliases for ABCA4 抗体
ATP binding cassette subfamily A member 4 (ABCA4) 抗体ATP-binding cassette, sub-family A (ABC1), member 4 (Abca4) 抗体
ATP binding cassette subfamily A member 4 (Abca4) 抗体
ATP binding cassette subfamily A member 4 (abca4) 抗体
ATP binding cassette subfamily A member 4 L homeolog (abca4.L) 抗体
ATP-binding cassette, sub-family A (ABC1), member 4a (abca4a) 抗体
ABC10 抗体
Abc10 抗体
abc10 抗体
ABCR 抗体
Abcr 抗体
abcr 抗体
ARMD2 抗体
armd2 抗体
AW050280 抗体
CORD3 抗体
cord3 抗体
D430003I15Rik 抗体
FFM 抗体
ffm 抗体
RMP 抗体
RmP 抗体
rmp 抗体
RP19 抗体
rp19 抗体
STGD 抗体
stgd 抗体
STGD1 抗体
stgd1 抗体
zgc:91823 抗体
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