anti-ADAMTS-Like 4 (ADAMTSL4) 抗体

ADAMTSL4 is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with protein with seven thrombospondin type 1 repeats. 再加上,我们可以发ADAMTSL4 蛋白 (4)ADAMTSL4 试剂盒 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ADAMTSL4 54507 Q6UY14
ADAMTSL4 229595 Q80T21
ADAMTSL4 310670 Q4FZU4
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antibodies-online.cn销售最多的anti-ADAMTSL4 抗体

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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: ADAMTSL4 Antibody [NBP1-84185] - Staining of human cell line A-431 shows positivity in plasma membrane & cytoplasm. Immunohistochemistry-Paraffin: ADAMTSL4 Antibody [NBP1-84185] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. 0.1 mL Log in to see 10至13个工作日
非结合性 IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded human colon cancer, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with ADAMTSL4 Polyclonal Antibody, Unconjugated  at 1:200 overnight at 4°C, followed by a conjugated secondary and DAB staining 100 μL Log in to see 3至7个工作日
小鼠 非结合性 IF, WB Western Blot analysis of ADAMTSL4 expression in transfected 293T cell line by ADAMTSL4 MaxPab polyclonal antibody.<br><br>Lane 1: ADAMTSL4 transfected lysate(46.64 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to ADAMTSL4 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Log in to see 11至12个工作日
非结合性 IHC, WB   100 μL Log in to see 16 Days
小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (71.43 KDa) . 100 μg Log in to see 11至12个工作日
FITC IF (p)   100 μL Log in to see 14至21个工作日
HRP IHC (p), WB   100 μL Log in to see 14至21个工作日
Cy3 IF (p)   100 μL Log in to see 14至21个工作日
Cy5.5 IF (p)   100 μL Log in to see 14至21个工作日
Cy5 IF (p)   100 μL Log in to see 14至21个工作日

通过反应活性、应用领域、克隆类型和共轭标记 ADAMTSL4 抗体

特性 应用范围 宿主 克隆类型 标记
Human ,
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Mouse (Murine) ,

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Rat (Rattus) ,

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引用最多的anti-ADAMTSL4 抗体

  1. Human Polyclonal ADAMTSL4 Primary Antibody for ICC, IF - ABIN4278318 : Gabriel, Wang, Bader, Ho, Majors, Hollyfield, Traboulsi, Apte: ADAMTSL4, a secreted glycoprotein widely distributed in the eye, binds fibrillin-1 microfibrils and accelerates microfibril biogenesis. in Investigative ophthalmology & visual science 2012 (PubMed)
    Show all 2 Pubmed References


Human ADAMTS-Like 4 (ADAMTSL4) interaction partners

  1. A recurrent pathogenic ADAMTSL4 variant is a major cause of early onset autosomal recessive ectopia lentis in a Cook Island Maori population and associated with a common haplotype, suggesting a founder effect.

  2. study reports a novel founder mutation in ADAMTSL4 gene in children of Bukharian Jewish origin presenting with early-onset bilateral ectopia lentis

  3. ADAMTSL4 mutations are the main cause for isolated ectopia lentis with an early onset of symptoms and possible severe ocular complications.

  4. Compound heterozygous c.1783dupT and c. 2594G>A mutations of ADAMTSL4 gene were causative mutations for this family with isolated non-syndromic ectopia lentis

  5. We have confirmed the gene and protein expression of ADAMTSL4 in human ocular tissue. The pattern of expression may suggest further functions of this gene beyond those suggested by its causative role in isolated ectopia lentis.

  6. Patients from a family with ectopia lentis et pupillae (ELP (显示 NR5A1 抗体)) in four generations have autosomal recessive ELP (显示 NR5A1 抗体) caused by novel mutations in ADAMTSL4.

  7. Mutations in ADAMTSL4 appear to cause earlier manifestation of ectopia lentis and are associated with increased axial length.

  8. Enhanced fibrillin-1 (显示 FBN1 抗体) deposition in the presence of ADAMTSL4 and colocalization of ADAMTSL4 with fibrillin-1 (显示 FBN1 抗体) in the ECM (显示 MMRN1 抗体) of cultured fibroblasts suggest a potential role for ADAMTSL4 in the formation or maintenance of the zonule.

  9. The results emphasize the association of ADAMTSL4 null mutations with isolated ectopia lentis and the presence of a founder mutation in the European population.

  10. This study confirms that homozygous mutations in ADAMTSL4 are associated with autosomal-recessive ectopia lentis in British families.

Mouse (Murine) ADAMTS-Like 4 (ADAMTSL4) interaction partners

  1. the first ADAMTSL4 mouse model, tvrm267, bearing a nonsense mutation in Adamtsl4



This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with anti-ADAMTS-Like 4 (ADAMTSL4) 抗体

  • ADAMTS like 4 (ADAMTSL4) 抗体
  • ADAMTS-like 4 (Adamtsl4) 抗体
  • ADAMTSL4 抗体
  • ECTOL2 抗体
  • Tsrc1 抗体

Protein level used designations for anti-ADAMTS-Like 4 (ADAMTSL4) 抗体

ADAMTS-like 4 , thrombospondin repeat containing 1 , ADAMTS-like protein 4 , ADAMTSL-4 , thrombospondin repeat-containing protein 1 , thrombospondin repeat protein 1

715768 Macaca mulatta
746960 Pan troglodytes
100059096 Equus caballus
100406425 Callithrix jacchus
100439893 Pongo abelii
100603837 Nomascus leucogenys
54507 Homo sapiens
483184 Canis lupus familiaris
100514576 Sus scrofa
507654 Bos taurus
229595 Mus musculus
310670 Rattus norvegicus
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