ABCC5 抗体
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected\; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ABCC5 抗体 (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCC5 抗体 (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCC5 抗体 (Alexa Fluor 488) | 人, 小鼠 | 兔 Polyclonal |
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| ABCC5 抗体 (Alexa Fluor 594) | 人, 小鼠 | 兔 Polyclonal |
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| ABCC5 抗体 (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCC5 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCC5 抗体 (Center) | 人, 小鼠 | 兔 Polyclonal |
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| ABCC5 抗体 | 人, 小鼠 | 兔 Polyclonal |
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| ABCC5 抗体 | 人 | 小鼠 Monoclonal |
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| ABCC5 抗体 | 人 | 大鼠 Monoclonal |
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| ABCC5 抗体 (AA 647-1409) | 人 | 兔 Polyclonal |
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| ABCC5 抗体 (AA 470-550) | 人, 小鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 647-1409
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 470-550
Latest Publications for our ABCC5 抗体
: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).
: "Effects of chronic renal failure on brain drug transporters in rats." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 1, pp. 39-46, (2011) (PubMed).
: "Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular ..." in: The American journal of pathology, Vol. 166, Issue 1, pp. 39-48, (2005) (PubMed).
: "Effects of chronic renal failure on brain drug transporters in rats." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 1, pp. 39-46, (2011) (PubMed).
: "Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular ..." in: The American journal of pathology, Vol. 166, Issue 1, pp. 39-48, (2005) (PubMed).
Aliases for ABCC5 抗体
ATP binding cassette subfamily C member 5 (ABCC5) 抗体ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (Abcc5) 抗体
ATP binding cassette subfamily C member 5 (Abcc5) 抗体
ATP binding cassette subfamily C member 5 L homeolog (abcc5.L) 抗体
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