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ABCB6 产品

(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. [provided by RefSeq, Jul 2008].

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Featured ABCB6 Categories

ABCB6 抗体

High quality antibodies with extensive validation data.

ABCB6 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ABCB6 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ABCB6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN564346
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7128119
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN129698
Quantity 100 μg
Datasheet Datasheet

Recommended ABCB6 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6212452
Quantity 96 tests
Datasheet Datasheet

Recommended ABCB6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121931
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305440
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3118335
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ABCB6 Products

Kaisar, Sivandzade, Bhalerao, Cucullo et al.: "Conventional and electronic cigarettes dysregulate the expression of iron transporters and detoxifying enzymes at the brain vascular endothelium: In vivo evidence of a gender-specific cellular ..." in: Neuroscience letters, Vol. 682, pp. 1-9, (2019) (PubMed).

Grebowski, Studzian, Bartosz, Pulaski: "Leishmania tarentolae as a host for heterologous expression of functional human ABCB6 transporter." in: Biochimica et biophysica acta, Vol. 1858, Issue 11, pp. 2617-2624, (2016) (PubMed).

Nakayama, Otsuka, Kobayashi, Okajima, Matsumoto, Hagiya, Inoue, Shuin, Nakajima, Tanaka, Ogura: "Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy." in: Scientific reports, Vol. 6, pp. 36478, (2016) (PubMed).

Liu, Li, Hung, Wang, Wang, Chen, Sheng, Fu, See, Foo, Low, Liany, Irwan, Liu, Yang, Chen, Yu, Yu, Niu, You, Zhou, Ma, Wang, Yan, Goh, Common, Lane, Sun, Zhou, Lu, Wang, Tian, Cao, Chen, Liu, Liu et al.: "Genome-wide linkage, exome sequencing and functional analyses identify ABCB6 as the pathogenic gene of dyschromatosis universalis hereditaria. ..." in: PLoS ONE, Vol. 9, Issue 2, pp. e87250, (2014) (PubMed).

Fukuda, Aguilar-Bryan, Vaxillaire, Dechaume, Wang, Dean, Moitra, Bryan, Schuetz: "Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8." in: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 8481-92, (2011) (PubMed).

Mitsuhashi, Miki, Senbongi, Yokoi, Yano, Miyazaki, Nakajima, Iwanaga, Yokoyama, Shibata, Seino: "MTABC3, a novel mitochondrial ATP-binding cassette protein involved in iron homeostasis." in: The Journal of biological chemistry, Vol. 275, Issue 23, pp. 17536-40, (2000) (PubMed).

Synonyms and alternative names related to ABCB6

ATP binding cassette subfamily B member 6 (Langereis blood group) (ABCB6), ATP binding cassette subfamily B member 6 (ABCB6), ATP-binding cassette, sub-family B (MDR/TAP), member 6a (abcb6a), ATP binding cassette subfamily B member 6 (Langereis blood group) (abcb6), ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Abcb6), ATP binding cassette subfamily B member 6 (Langereis blood group) (Abcb6), ATP binding cassette subfamily B member 6 (Abcb6), 1200005B17Rik, ABC, ABC14, ABCB6, abcb6, LAN, MCOPCB7, MTABC3, PRP, umat

Protein level used designations for ABCB6

  • ATP-binding cassette, sub-family B (MDR/TAP), member 6
  • ATP-binding cassette sub-family B member 6, mitochondrial
  • ATP-binding cassette, sub-family B, member 6
  • ATP-binding cassette sub-family B member 6, mitochondrial-like
  • ATP-binding cassette half-transporter
  • P-glycoprotein-related protein
  • mitochondrial ABC transporter 3
  • mt-ABC transporter 3
  • ubiquitously-expressed mammalian ABC half transporter
  • ATG9 autophagy related 9 homolog A
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