ABCB1 抗体
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].
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Latest Publications for our ABCB1 抗体
: "Association Analysis of Single-Cell RNA Sequencing and Proteomics Reveals a Vital Role of Ca2+ Signaling in the Determination of Skeletal Muscle Development Potential." in: Cells, Vol. 9, Issue 4, (2021) (PubMed).: "Hypoxia-tropic Protein Nanocages for Modulation of Tumor- and Chemotherapy-Associated Hypoxia." in: ACS nano, Vol. 13, Issue 1, pp. 236-247, (2019) (PubMed).
: "PAMAM dendrimer grafted cellulose paper scaffolds as a novel in vitro 3D liver model for drug screening applications." in: Colloids and surfaces. B, Biointerfaces, Vol. 172, pp. 346-354, (2019) (PubMed).
: "Manganese transporter Slc30a10 controls physiological manganese excretion and toxicity." in: The Journal of clinical investigation, Vol. 129, Issue 12, pp. 5442-5461, (2019) (PubMed).
: "MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." in: Gene, Vol. 652, pp. 48-58, (2018) (PubMed).
: "Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance." in: Cell death & disease, Vol. 9, Issue 4, pp. 419, (2018) (PubMed).
: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).
: "Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer." in: Stem cells (Dayton, Ohio), Vol. 34, Issue 11, pp. 2613-2624, (2018) (PubMed).
: "A novel polysaccharide from Sargassum integerrimum induces apoptosis in A549 cells and prevents angiogensis in vitro and in vivo." in: Scientific reports, Vol. 6, pp. 26722, (2018) (PubMed).
: "Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis." in: Oncotarget, Vol. 7, Issue 40, pp. 64575-64588, (2018) (PubMed).
Aliases for ABCB1 抗体
ATP binding cassette subfamily B member 1 (ABCB1) 抗体ATP binding cassette subfamily B member 1A (Abcb1a) 抗体
ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) 抗体
ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 抗体
ATP binding cassette subfamily B member 1 (Abcb1) 抗体
ABC20 抗体
Abcb1 抗体
ABCB1 抗体
CD243 抗体
CLCS 抗体
GP170 抗体
mdr 抗体
MDR1 抗体
Mdr1 抗体
Mdr1a 抗体
Mdr1b 抗体
P-GP 抗体
p-gp 抗体
PGP1 抗体
Pgy-1 抗体
PGY1 抗体
Pgy1 抗体
xemdr 抗体
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