ABCA1 抗体
(ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ABCA1 抗体 (AA 1100-1300) | 人 | 兔 Polyclonal |
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| ABCA1 抗体 (AA 1248-1350) | 人 | 绵羊 Polyclonal |
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| ABCA1 抗体 (Extracellular Loop, N-Term) | 大鼠 | 小鼠 Monoclonal |
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| ABCA1 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA1 抗体 (AA 2253-2257) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA1 抗体 | 人 | 小鼠 Monoclonal |
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| ABCA1 抗体 (Alexa Fluor 680) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA1 抗体 (Alexa Fluor 555) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA1 抗体 (Biotin) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA1 抗体 (Alexa Fluor 647) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA1 抗体 (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA1 抗体 (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA1 抗体 (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA1 抗体 | 人 | 小鼠 Monoclonal |
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| ABCA1 抗体 (AA 1112-1180) | 人, 小鼠, Golden Syrian Hamster | 兔 Polyclonal |
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| ABCA1 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ABCA1 抗体 | 人 | 小鼠 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- ELISA (ELISA: 所列应用)
- IC (Immunochromatography: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1100-1300
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- IC (Immunochromatography: 所列应用)
- 适用
- 人
- 宿主
- 绵羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1248-1350
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 8A274
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Extracellular Loop, N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 2253-2257
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, Golden Syrian Hamster
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1112-1180
Latest Publications for our ABCA1 抗体
: "Macrophage iron retention aggravates atherosclerosis: Evidence for the role of autocrine formation of hepcidin in plaque macrophages." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1865, Issue 2, pp. 158531, (2020) (PubMed).
: "Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression." in: Journal of pharmacological sciences, Vol. 142, Issue 1, pp. 9-15, (2020) (PubMed).
: "Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress." in: Cancer research, Vol. 80, Issue 2, pp. 189-203, (2020) (PubMed).
: "Liver X Receptor Agonist Therapy Prevents Diffuse Alveolar Hemorrhage in Murine Lupus by Repolarizing Macrophages." in: Frontiers in immunology, Vol. 9, pp. 135, (2019) (PubMed).
: "Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux." in: Oncogene, Vol. 38, Issue 12, pp. 2135-2150, (2019) (PubMed).
: "OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1865, Issue 1, pp. 161-180, (2019) (PubMed).
: "Nutritionally Derived Metabolic Cues Typical of the Obese Microenvironment Increase Cholesterol Efflux Capacity of Adipose Tissue Macrophages." in: Molecular nutrition & food research, Vol. 63, Issue 2, pp. e1800713, (2019) (PubMed).
: "Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages." in: Molecular and cellular biology, Vol. 39, Issue 5, (2019) (PubMed).
: "Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages." in: Journal of lipid research, Vol. 60, Issue 3, pp. 506-515, (2019) (PubMed).
: "E3317 promotes cholesterol efflux in macrophage cells via enhancing ABCA1 expression." in: Biochemical and biophysical research communications, Vol. 504, Issue 1, pp. 68-74, (2019) (PubMed).
: "Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression." in: Journal of pharmacological sciences, Vol. 142, Issue 1, pp. 9-15, (2020) (PubMed).
: "Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress." in: Cancer research, Vol. 80, Issue 2, pp. 189-203, (2020) (PubMed).
: "Liver X Receptor Agonist Therapy Prevents Diffuse Alveolar Hemorrhage in Murine Lupus by Repolarizing Macrophages." in: Frontiers in immunology, Vol. 9, pp. 135, (2019) (PubMed).
: "Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux." in: Oncogene, Vol. 38, Issue 12, pp. 2135-2150, (2019) (PubMed).
: "OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1865, Issue 1, pp. 161-180, (2019) (PubMed).
: "Nutritionally Derived Metabolic Cues Typical of the Obese Microenvironment Increase Cholesterol Efflux Capacity of Adipose Tissue Macrophages." in: Molecular nutrition & food research, Vol. 63, Issue 2, pp. e1800713, (2019) (PubMed).
: "Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages." in: Molecular and cellular biology, Vol. 39, Issue 5, (2019) (PubMed).
: "Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages." in: Journal of lipid research, Vol. 60, Issue 3, pp. 506-515, (2019) (PubMed).
: "E3317 promotes cholesterol efflux in macrophage cells via enhancing ABCA1 expression." in: Biochemical and biophysical research communications, Vol. 504, Issue 1, pp. 68-74, (2019) (PubMed).
Aliases for ABCA1 抗体
ATP binding cassette subfamily A member 1 (ABCA1) 抗体ATP binding cassette subfamily A member 1 (Abca1) 抗体
ATP-binding cassette, sub-family A (ABC1), member 1 (ABCA1) 抗体
ATP binding cassette subfamily A member 1 (abca1) 抗体
ATP-binding cassette, sub-family A (ABC1), member 1 (Abca1) 抗体
ATP-binding cassette A1 (ABCA1) 抗体
ATP-binding cassette, sub-family A (ABC1), member 1B (abca1b) 抗体
ABC-1 抗体
ABC1 抗体
Abc1 抗体
ABCA1 抗体
Arabidopsis thaliana ATP-binding cassette A1 抗体
AtABCA1 抗体
ATP-binding cassette A1 抗体
CERP 抗体
HDLDT1 抗体
im:7136239 抗体
sb:cb407 抗体
TGD 抗体
wu:fa07e06 抗体
zgc:171581 抗体
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