anti-Podocalyxin-Like (PODXL) 抗体产品概述

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anti-Podocalyxin-Like 抗体 (PODXL)
在www.antibodies-online.cn可供349 Podocalyxin-Like (PODXL) 抗体的25不同的供货商。 再加上,我们可以发Podocalyxin-Like 试剂盒 (48)Podocalyxin-Like 蛋白 (32)和数多这个蛋白质的别的产品。 总共436 Podocalyxin-Like产品已列进来了。
别名:
AW121214, cPCLP1, fc18d02, Gp135, Gp200, Ly102, MEP21, PC, PCLP, PCLP-1, PCLP1, podocalyxin, Podxl, wu:fc18d02

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  1. Mouse (Murine) Monoclonal PODXL Primary Antibody for FACS - ABIN1108688 : Doyonnas, Nielsen, Chelliah, Drew, Hara, Miyajima, McNagny: Podocalyxin is a CD34-related marker of murine hematopoietic stem cells and embryonic erythroid cells. in Blood 2005 (PubMed)
    Show all 4 references for 1108688

  2. Mouse (Murine) Monoclonal PODXL Primary Antibody for FACS - ABIN1108687 : Minegishi, Suzuki, Yokomizo, Pan, Fujimoto, Takahashi, Hara, Miyajima, Nishikawa, Yamamoto: Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos. in Blood 2003 (PubMed)
    Show all 4 references for 1108687

  3. Mouse (Murine) Monoclonal PODXL Primary Antibody for FACS - ABIN1108686 : Minehata, Mukouyama, Sekiguchi, Hara, Miyajima: Macrophage colony stimulating factor modulates the development of hematopoiesis by stimulating the differentiation of endothelial cells in the AGM region. in Blood 2002 (PubMed)
    Show all 4 references for 1108686

  4. Mouse (Murine) Monoclonal PODXL Primary Antibody for FACS - ABIN2853591 : Hara, Nakano, Tanaka, Tamura, Sekiguchi, Minehata, Copeland, Jenkins, Okabe, Kogo, Mukouyama, Miyajima: Identification of podocalyxin-like protein 1 as a novel cell surface marker for hemangioblasts in the murine aorta-gonad-mesonephros region. in Immunity 2000 (PubMed)
    Show all 4 references for 2853591

  5. Mouse (Murine) Monoclonal PODXL Primary Antibody for FACS, ICC - ABIN4899591 : Maltby, Hughes, Zbytnuik, Paulson, McNagny: Podocalyxin selectively marks erythroid-committed progenitors during anemic stress but is dispensable for efficient recovery. in Experimental hematology 2008 (PubMed)
    Show all 3 references for 4899591

  6. Mouse (Murine) Monoclonal PODXL Primary Antibody for FACS - ABIN4896361 : Yuri, Nishikawa, Yanagawa, Jo, Yanagawa: Maintenance of Mouse Nephron Progenitor Cells in Aggregates with Gamma-Secretase Inhibitor. in PLoS ONE 2015 (PubMed)

  7. Human Polyclonal PODXL Primary Antibody for ELISA, WB - ABIN190772 : Nielsen, Graves, Chelliah, Vogl, Roskelley, McNagny: The CD34-related molecule podocalyxin is a potent inducer of microvillus formation. in PLoS ONE 2007 (PubMed)

  8. Human Polyclonal PODXL Primary Antibody for WB - ABIN2781991 : Casey, Neville, Liu, Plummer, Cicek, Krumroy, Curran, McGreevy, Catalona, Klein, Witte: Podocalyxin variants and risk of prostate cancer and tumor aggressiveness. in Human molecular genetics 2006 (PubMed)

  9. Human Polyclonal PODXL Primary Antibody for IHC, WB - ABIN2781992 : Qiu, Xiang, Li, Krishnamoorthy, Chen, Wang: Profiling TRA-1-81 antigen distribution on a human embryonic stem cell. in Biochemical and biophysical research communications 2008 (PubMed)

  10. Human Polyclonal PODXL Primary Antibody for IF (p), IHC (p) - ABIN675264 : Xing, Ye, Chen, Hu, Chen: Hydrochloride pioglitazone protects diabetic rats against podocyte injury through preserving glomerular podocalyxin expression. in Arquivos brasileiros de endocrinologia e metabologia 2014 (PubMed)

更多抗Podocalyxin-Like的相互作用对抗体

Human Podocalyxin-Like (PODXL) interaction partners

  1. PODXL enhances motility and invasiveness through an increase in gelsolin-actin interactions in cell protrusions.

  2. Results identify an anti-metastatic miRNA, miR (显示 MLXIP 抗体)-5100, that decreases the metastatic ability of pancreatic cancer partially by suppressing expression of PODXL.

  3. Results indicate that urinary podocalyxin is not only an early marker but also a treatment target for diabetic nephropathy (DN).

  4. Obese subjects showed evidence of renal alteration through the detection of a higher number of urinary podocalyxin positive cells.

  5. Data show that both mucin16 (MUC16 (显示 MUC16 抗体)) and podocalyxin (PODXL)-E-selectin (显示 SELE 抗体)-mediated interactions are mechanically stronger than like L-selectin (显示 SELL 抗体) interactions at the single-molecule level.

  6. In gastric cancer, PODXL expression by the polyclonal antibody HPA2110 is an independent marker of poor prognosis.

  7. PCX (显示 PC 抗体) promotes cisplatin chemoresistance in osteosarcoma cells through a PI3Kdependent mechanism.

  8. EZR (显示 EZR 抗体), CLIC5 (显示 CLIC5 抗体) and PODXL are overexpressed in hepatocellular carcinoma and may have a role in cell migration and invasiveness

  9. PODXL up-regulates the expression level of Bmi1 (显示 BMI1 抗体) in OTSCC cells.

  10. podocalyxin to be an independent factor for poor prognosis in PDAC. To our knowledge, this is the first such report of its prognostic value.

Mouse (Murine) Podocalyxin-Like (PODXL) interaction partners

  1. Podxl-KO led to heightened G-CSF (显示 CSF3 抗体) activation of Rap1a (显示 RAP1A 抗体)(GTP (显示 AK3 抗体)), and Rap1a (显示 RAP1A 抗体)(GTP (显示 AK3 抗体)) inhibition attenuated Podxl-KO neutrophil migration. Studies have revealed novel roles for Podxl as an important modulator of neutrophil and monocyte formation and of Rap1a (显示 RAP1A 抗体) activation during stress hematopoiesis.

  2. Podxl-overexpression in neural stem/progenitor cells leads to an up-regulation of Annexin A2 (显示 ANXA2 抗体).

  3. when endogenous podocalyxin was removed from highly metastatic 4T1 mammary tumor cells there was a decrease in collective invasion . Podocalyxin is a tumor cell-intrinsic regulator of experimental collective tumor cell invasion and tumor budding.

  4. Podocalyxin has a role in glioblastoma multiforme cell invasion and proliferation via beta-catenin (显示 CTNNB1 抗体) signaling

  5. Loss of podocalyxin from the lung vasculature results in changes to the lung structure and function including increased lung volume when inflated under constant pressure (25 cm H2O) and changes to the matrix composition.

  6. CTGF (显示 CTGF 抗体) is an important mediator of high glucose-induced podocyte damage and decreases the protein level of podocalyxin by the ERK1/2 (显示 MAPK1/3 抗体) pathway.

  7. platelet Podxl is involved in the control of hemostasis acting as a platelet co-stimulator, likely due to its pro-adhesive properties

  8. Full-length recombinant murine podocalyxin recruits NHERF-1 (显示 SLC9A3R1 抗体) to the apical domain. Ectopic expression in human & canine epithelial cells leads to microvilli formation on an apical domain extending laterally to the junctional complexes.

  9. Podocalyxin plays multiple roles in neural development

  10. PODXL may act as a costimulator of agonists in the activation of platelets and formation of a stable thrombus.

Podocalyxin-Like (PODXL) 抗原简介

Antigen Summary

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Alternative names and synonyms associated with Podocalyxin-Like (PODXL)

  • podocalyxin-like (PODXL) 抗体
  • si:dkey-146n1.1 (si:dkey-146n1.1) 抗体
  • podocalyxin-like (LOC100614602) 抗体
  • podocalyxin-like (Podxl) 抗体
  • podocalyxin-like (LOC100512201) 抗体
  • podocalyxin-like protein 1 (PCLP1) 抗体
  • AW121214 抗体
  • cPCLP1 抗体
  • fc18d02 抗体
  • Gp135 抗体
  • Gp200 抗体
  • Ly102 抗体
  • MEP21 抗体
  • PC 抗体
  • PCLP 抗体
  • PCLP-1 抗体
  • PCLP1 抗体
  • podocalyxin 抗体
  • Podxl 抗体
  • wu:fc18d02 抗体

Protein level used designations for anti-Podocalyxin-Like (PODXL) 抗体

podocalyxin-like , podocalyxin-like protein 1-like , GCTM-2 antigen , podocalyxin , podocalyxin-like protein 1 , PC-like protein 1 , Podocalyxin-like protein 1 , thrombomucin

GENE ID SPECIES
472604 Pan troglodytes
563365 Danio rerio
100462597 Pongo abelii
100614602 Pan troglodytes
5420 Homo sapiens
27205 Mus musculus
192181 Rattus norvegicus
482252 Canis lupus familiaris
100727578 Cavia porcellus
395755 Gallus gallus
616366 Bos taurus
101106679 Ovis aries
100512201 Sus scrofa
100009552 Oryctolagus cuniculus
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