TLR4 (TLR4) ELISA试剂盒产品概述

Full name:
Toll-Like Receptor 4 ELISA试剂盒 (TLR4)
在www.antibodies-online.cn可供58 Toll-Like Receptor 4 (TLR4) ELISA试剂盒的11不同的供货商。 再加上,我们可以发TLR4 抗体 (613)TLR4 蛋白 (21)和数多这个蛋白质的别的产品。 总共707 TLR4产品已列进来了。
别名:
ARMD10, CD284, Lps, Ly87, Ran/M1, Rasl2-8, TLR-4, TOLL

引用最多的TLR4 ELISA试剂盒

  1. Mouse (Murine) TLR4 ELISA Kit for Sandwich ELISA - ABIN424269 : Campo, Avenoso, DAscola, Prestipino, Scuruchi, Nastasi, Calatroni, Campo: Inhibition of hyaluronan synthesis reduced inflammatory response in mouse synovial fibroblasts subjected to collagen-induced arthritis. in Archives of biochemistry and biophysics 2012 (PubMed)
    Show all 14 references for 424269

  2. Human TLR4 ELISA Kit for Sandwich ELISA - ABIN414556 : Kacerovsky, Andrys, Hornychova, Pliskova, Lancz, Musilova, Drahosova, Bolehovska, Tambor, Jacobsson: Amniotic fluid soluble Toll-like receptor 4 in pregnancies complicated by preterm prelabor rupture of the membranes. in The journal of maternal-fetal & neonatal medicine 2012 (PubMed)
    Show all 13 references for 414556

  3. Rat (Rattus) TLR4 ELISA Kit for Sandwich ELISA - ABIN416209 : Kusano, Etoh, Inomata, Shiraishi, Kitano: CO(2) pneumoperitoneum increases secretory IgA levels in the gut compared with laparotomy in an experimental animal model. in Surgical endoscopy 2014 (PubMed)
    Show all 5 references for 416209

适于 TLR4 相互作用对的更多 ELISA 试剂盒

Human Toll-Like Receptor 4 (TLR4) interaction partners

  1. Type I IFN is detrimental to the host, and dysregulation of iron homeostasis genes may explain lower bacteria survival in cGAS(-/-) and TLR4(-/-) cells.

  2. Here the authors show that MAL (显示 MAL ELISA试剂盒) TIR domains spontaneously and reversibly form filaments in vitro. They also form cofilaments with TLR4 TIR domains and induce formation of MyD88 (显示 MYD88 ELISA试剂盒) assemblies.

  3. Experiments demonstrate for the first time that palmitic acid activation of TLR4 occurs in response to direct molecular interactions between palmitic acid and MD-2 (显示 LY96 ELISA试剂盒); suggest a likely molecular mechanism for palmitic acid induction of pro-inflammatory immune responses in human dendritic cells expressing TLR4.

  4. In LPS-stimulated HEK293 cells with low CD14 and high (显示 IRF6 ELISA试剂盒) TLR4, no accumulation of PI(4,5)P2 occurred. With an increasing amount of CD14 and decrease of TLR4, 2 peaks of PI(4,5)P2 appeared, approaching those found in LPS-stimulated cells expressing CD14 alone. This suggests that LPS-induced accumulation of PI(4,5)P2 that maximizes TLR4 signaling is controlled by CD14, whereas TLR4 can fine tune this via PI(4,5)P2 turnover.

  5. TLR4 coding SNPs Asp299Gly and Thr399Ile might be used as genetic susceptibility alleles for POAG

  6. Estradiol alters the immune-responsiveness of cultured HECECs to TLR2 (显示 TLR2 ELISA试剂盒) and TLR4 ligands in a complex fashion that appears to vary with bacterial ligand, TLR subtype, and duration of exposure

  7. Ligand-driven triggering of TLR-3 (显示 TLR3 ELISA试剂盒), -4, NOD2 (显示 NOD2 ELISA试剂盒), and DC-SIGN (显示 CD209 ELISA试剂盒), despite reducing viral replication, markedly increased the capacity of infected dendritic cells to stimulate HIV-specific cytotoxic T-cells.

  8. The study demonstrated that HIV infection sensitizes Kupffer cells to the proinflammatory effects of lipopolysaccharides in a TLR4-dependent manner.

  9. The lipid flippases, ATP8B1 (显示 ATP8B1 ELISA试剂盒) and ATP11A (显示 ATP11A ELISA试剂盒) are novel elements of the innate immune response that are essential to attenuate the inflammatory response, possibly by mediating endotoxin-induced internalization of TLR4.

  10. these findings identify new compounds for antagonizing TLR2 (显示 TLR2 ELISA试剂盒) and TLR4 activation and define structural properties of POPG analogs for discriminating between two TLR systems.

Mouse (Murine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. Stimulation of the TLR4-TRIF (显示 RNF138 ELISA试剂盒) pathway can protect against the development of allergic airway disease and that a TRIF (显示 RNF138 ELISA试剂盒)-dependent adjuvant effect on CD4 (显示 CD4 ELISA试剂盒)(+) ICOS (显示 ICOS ELISA试剂盒)(+) T-cell responses may be a contributing mechanism.

  2. HMGB1 (显示 HMGB1 ELISA试剂盒) activates the NF-kappaB (显示 NFKB1 ELISA试剂盒) and JNK (显示 MAPK8 ELISA试剂盒)/p38 (显示 CRK ELISA试剂盒) pathways through TLR4/MyD88 (显示 MYD88 ELISA试剂盒)-dependent signaling and induces an inflammatory response in lungs exposed to cigarette smoke.

  3. Findings reveal that TLR4 mutant significantly abated the intestinal IR injury and ALI at least in part by alleviating the inflammatory response and oxidative stress.

  4. These findings indicate that TLR2 (显示 TLR2 ELISA试剂盒) and TLR4 are required to control Brucella microti infection in mice and that this effect could be related to its participation in the maturation of dendritic cells and the generation of specific CD8 (显示 CD8A ELISA试剂盒)(+) Tc cells.

  5. Monophosphoryl lipid A stimulation of a TLR4-TRIF (显示 RNF138 ELISA试剂盒)-PI3K-Akt (显示 AKT1 ELISA试剂盒) pathway prevents lipopolysaccharide-induced ERK (显示 EPHB2 ELISA试剂盒) activation in the medullar thick ascending limb.

  6. Results show that TLR4 plays a critical role in the effects of dietary fat composition on the development of hepatic steatosis, inflammation, and injury consistent with nonalcoholic steatohepatitis.

  7. FasL (显示 FASL ELISA试剂盒) expression in splenic CD5 (显示 CD5 ELISA试剂盒)(+)CD1d (显示 CD1D ELISA试剂盒)(hi) B cells was decreased compared to the control group after TLR4 ligation.

  8. Stimulation of murine peritoneal macrophages with LPS induces biphasic accumulation of PI(4,5)P2 with peaks at 10 and 60-90 min that were still seen after silencing of TLR4 expression, questioning the involvement of TLR4 in this process.

  9. Data suggest that the transmembrane domains of Tlr4 and Tlr6 (显示 TLR6 ELISA试剂盒) have essential roles in Tlr4/Tlr6 (显示 TLR6 ELISA试剂盒)/Cd36 (显示 CD36 ELISA试剂盒) receptor multimerization and activation; disruption of receptor multimerization (here, using a recombinant peptide fragment from Tlr4 transmembrane domain) reduces secretion of proinflammatory mediators from microglia and ultimately rescues neurons from death.

  10. This study demonstrated that TLR4 deficiency contributes to regulating microglia to switch to the M2 phenotype, which ameliorates neurological impairment after traumatic brain injury in mice.

Cow (Bovine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. TLR4 polymorphisms are associated with lower reproductive Performance.

  2. As a pilot study, the present results revealed that identified SNPs in IL8 (显示 IL8 ELISA试剂盒) and TLR4 genes can be used as a genetic marker and predisposing factor for resistance/susceptibility to digital dermatitis in dairy cows. However, TLR4 gene may be a potential candidate for such disease.

  3. Transcription levels of TLR2 (显示 TLR2 ELISA试剂盒), TLR4, and CD14 (显示 CD14 ELISA试剂盒) in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.

  4. Bovine viral diarrhea virus type 2 infection modulates TLR4 responsiveness in differentiated myeloid cells.

  5. TLR2 (显示 TLR2 ELISA试剂盒) and TLR4 mediate innate response against Cryptosporidium parvum in bovine intestinal epithelial cells.

  6. TLR4 polymorphisms are associated with susceptibility to Mycobacterium avium ssp. paratuberculosis infection in Holsteins

  7. positive correlation between lower neutrophil apoptosis and higher expression of TLR2 (显示 TLR2 ELISA试剂盒) and TLR4 with the formation of NETs and change in surface architecture.

  8. Studied SNPs in the bovine toll-like receptor 4 (TLR4) and monocyte chemo attractant protein-1(CCL2 (显示 CCL2 ELISA试剂盒)) genes.

  9. Studied bovine TLR4 gene in mastitis resistance by association as well as expression profiling analysis in crossbred cattle.

  10. Findings indicate that intervertebral disc (IVD (显示 IVD ELISA试剂盒)) cells constitutively express TLR4.

Rabbit Toll-Like Receptor 4 (TLR4) interaction partners

  1. TLR2 (显示 TLR2 ELISA试剂盒), 3, 4, and 8 mRNA expression is strongly upregulated and correlates with the progression of atherosclerosis in the aorta. Fluvastatin significantly inhibited this progress and reduced inflammation via TLR downregulation.

  2. The expression of TLR4 protein and mRNA, the level of activated NF-kappaB (显示 NFKB1 ELISA试剂盒) (p65 (显示 SYT1 ELISA试剂盒)) were respectively detected.

  3. Lipopolysaccharide upregulates the expression of rabbit TLR2 (显示 TLR2 ELISA试剂盒) and 4 in the uterine body and horn, and the expression of TLR4 in the ovary.

  4. Polydatin might have a protective effect on lung ischemia/reperfusion injury by down-regulating TLR4 and NF-kappaB (显示 NFKB1 ELISA试剂盒) expression, then inhibiting the release of mediators of inflammation as ICAM-1 (显示 ICAM1 ELISA试剂盒).

  5. TLR4 expression is upregulated in the brain after experimental subarachnoid haemorrhage

  6. The elevated expression of TLR4 was detected after SAH (显示 ACSM3 ELISA试剂盒) and peaked on day 3 and 5. TLR4 is increasingly expressed in a parallel time course to the development of cerebral vasospasm in a rabbit experimental model of SAH (显示 ACSM3 ELISA试剂盒).

Pig (Porcine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. These results further confirm the involvement of the TLR4 signaling pathway in resistance to E. coli F18 (显示 MAMLD1 ELISA试剂盒) in Meishan weaned piglets.

  2. Data suggest expression of TLR4 and NFKB (nuclear factor kappa B) are regulated by dietary factors affecting innate immunity; here, Lactobacillus acidophilus in feed down-regulates expression of TLR4 and NFKB in mononuclear cells after LPS (显示 IRF6 ELISA试剂盒) challenge.

  3. At 30 days after autotransplantation of a pig kidney, mRNA expression increases for TLR4.

  4. Data suggest TLR2 (显示 TLR2 ELISA试剂盒), TLR4, and calcium signaling in enterocytes play principal roles in mucosal immunity against enterotoxigenic Escherichia coli; probiotic Lactobacillus delbrueckii and its extracellular polysaccharides appear to stimulate TLR2 (显示 TLR2 ELISA试剂盒)/TLR4.

  5. TLR2 (显示 TLR2 ELISA试剂盒) is required for the suppression of TLR4 signaling activation.

  6. The current study screened for single nucleotide polymorphisms (SNPs) in the TLR4 gene and tested their association with Salmonella fecal shedding.

  7. The role of TLR2 (显示 TLR2 ELISA试剂盒), TLR4 and RP105 (显示 CD180 ELISA试剂盒)/MD1 (显示 LY86 ELISA试剂盒) in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (显示 CLPTM1 ELISA试剂盒), is reported.

  8. Data suggest expression of TLR4 in liver can be regulated by dietary factors; here, supplementation with aspartate down-regulates expression of TLR4 in liver in a model of liver disease.

  9. Fish Oil attenuates the activation of the HPA (显示 HPSE ELISA试剂盒) axis induced by LPS (显示 IRF6 ELISA试剂盒) challenge. So it may be associated with decreasing the production of brain or peripheral proinflammatory cytokines through inhibition of TLR4 and NOD signaling pathways in weaned pigs.

  10. Single nucleotide polymorphisms in TLR4 is associated with immune response to gram-negative bacterial infections.

Horse (Equine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. The research findings suggest that Th17 cells are involved in active equine inflammatory bowel disease, and that TLR4 expression was increased in affected horses.

  2. A low steady expression of TLR4, MD-2 (显示 LY96 ELISA试剂盒) and CD14 (显示 CD14 ELISA试剂盒) mRNA was demonstrated for the intestinal samples with no variation between the intestinal segments analysed.

  3. In the present study, the authors show that TLR4 expression is significantly decreased following the exogenous expression of BPV-1 E2 and E7 in primary equine fibroblasts.

  4. evidence that pulmonary intravascular macrophages are equipped with TLR4 to handle and rapidly respond to circulating endotoxins

  5. TLR4/MD-2 (显示 LY96 ELISA试剂盒) complex is responsible for recognition of Rhodococcus spheroides lipopolysaccharide as an agonist in equine cells.

TLR4 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TLR4

  • toll-like receptor 4 (TLR4) Elisa Kit
  • toll-like receptor 4 (Tlr4) Elisa Kit
  • ARMD10 Elisa Kit
  • CD284 Elisa Kit
  • Lps Elisa Kit
  • Ly87 Elisa Kit
  • Ran/M1 Elisa Kit
  • Rasl2-8 Elisa Kit
  • TLR-4 Elisa Kit
  • TOLL Elisa Kit

Protein level used designations for TLR4

hToll , homolog of Drosophila toll , lipopolysaccharide response , toll4 , Toll-like receptor4 protein , Toll-like receptor 4-like protein

GENE ID SPECIES
7099 Homo sapiens
21898 Mus musculus
417241 Gallus gallus
29260 Rattus norvegicus
281536 Bos taurus
100009497 Oryctolagus cuniculus
100724803 Cavia porcellus
403417 Canis lupus familiaris
399541 Sus scrofa
493698 Felis catus
100066890 Equus caballus
100860955 Capra hircus
554263 Ovis aries
100980644 Pan paniscus
100689329 Cricetulus griseus
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