anti-HLA-A (HLA-A) 抗体产品概述

Full name:
anti-Major Histocompatibility Complex, Class I, A 抗体 (HLA-A)
在www.antibodies-online.cn可供185 Major Histocompatibility Complex, Class I, A (HLA-A) 抗体的21不同的供货商。 再加上,我们可以发HLA-A 蛋白 (44)HLA-A 试剂盒 (5)和数多这个蛋白质的别的产品。 总共240 HLA-A产品已列进来了。
别名:
HLAA
列出全部抗体 基因 基因ID UniProt
HLA-A 3105 P30443 , P04439
HLA-A    
HLA-A    

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引用最多的anti-HLA-A 抗体

  1. Human Monoclonal HLA-A Primary Antibody for FACS, ICFC - ABIN2659031 : Nicodemus, Wang, Lucas, Varghese, Berek: Toll-like receptor-3 as a target to enhance bioactivity of cancer immunotherapy. in American journal of obstetrics and gynecology 2010 (PubMed)
    Show all 10 references for 2659031

  2. Human Monoclonal HLA-A Primary Antibody for FACS - ABIN2657515 : Darrow, Slingluff, Seigler: The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes. Evidence for shared tumor antigens. in Journal of immunology (Baltimore, Md. : 1950) 1989 (PubMed)
    Show all 9 references for 2657515

  3. Human Monoclonal HLA-A Primary Antibody for FACS - ABIN2657919 : Ayyoub, Taub, Keohan, Hesdorffer, Metthez, Memeo, Mansukhani, Hibshoosh, Hesdorffer, Valmori: The frequent expression of cancer/testis antigens provides opportunities for immunotherapeutic targeting of sarcoma. in Cancer immunity 2004 (PubMed)
    Show all 9 references for 2657919

  4. Human Monoclonal HLA-A Primary Antibody for FACS, IF - ABIN2663732 : Barbatis, Woods, Morton, Fleming, McMichael, McGee: Immunohistochemical analysis of HLA (A, B, C) antigens in liver disease using a monoclonal antibody. in Gut 1982 (PubMed)
    Show all 9 references for 2663732

  5. Human Monoclonal HLA-A Primary Antibody for FACS, ICFC - ABIN2658757 : De Felice, Turco, Costanzo, Corbo, Ferrone, Venuta: Inhibition by anti-HLA class I mAb of IL-2 and IL-2 receptor synthesis in lymphocytes stimulated with PHA-P. in Cellular immunology 1990 (PubMed)
    Show all 9 references for 2658757

  6. Human Monoclonal HLA-A Primary Antibody for FACS - ABIN2661910 : Fayen, Huang, Ferrone, Tykocinski: Negative signaling by anti-HLA class I antibodies is dependent upon two triggering events. in International immunology 1998 (PubMed)
    Show all 9 references for 2661910

  7. Human Monoclonal HLA-A Primary Antibody for FACS, IP - ABIN2662341 : Geppert, Wacholtz, Patel, Lightfoot, Lipsky: Activation of human T cell clones and Jurkat cells by cross-linking class I MHC molecules. in Journal of immunology (Baltimore, Md. : 1950) 1989 (PubMed)
    Show all 9 references for 2662341

  8. Human Monoclonal HLA-A Primary Antibody for FACS - ABIN4900774 : Loubaki, Chabot, Bazin: Involvement of the TNF-α/TGF-β/IDO axis in IVIg-induced immune tolerance. in Cytokine 2015 (PubMed)
    Show all 2 references for 4900774

  9. Mouse (Murine) Polyclonal HLA-A Primary Antibody for IHC, WB - ABIN3023100 : Parham, Lomen, Lawlor, Ways, Holmes, Coppin, Salter, Wan, Ennis: Nature of polymorphism in HLA-A, -B, and -C molecules. in Proceedings of the National Academy of Sciences of the United States of America 1988 (PubMed)
    Show all 2 references for 3023100

更多抗HLA-A的相互作用对抗体

Human Major Histocompatibility Complex, Class I, A (HLA-A) interaction partners

  1. this study shows that alpha3-deletion isoform of HLA-A11 plays role in the immune escape of HIV-1

  2. Data suggest that personalized peptide vaccine (PPV (显示 PPP6C 抗体)) with these nine CTL epitope peptides exhibit a good safety profile and positive immunological responses in HLA-A11+ or -A33 (显示 GPA33 抗体)+ cancer patients.

  3. findings demonstrate that gliadins contain epitopes that elicit CD8 (显示 CD8A 抗体)+ T cell responses restricted by HLA class I (显示 MICA 抗体) A*0101 and B*0801 molecules

  4. Data suggest that only a small fraction of HLA-A*02:01- (HA)-binding ESO peptides are immunogenic, namely those that have high peptide-binding strength and peptide/HA complex stability. This study involved comparison of in silico-predicted and observed cytotoxic T-lymphocyte recognition of tumor antigen epitopes in melanoma patients and transgenic/knockout mice. (ESO = tumor antigen NY-ESO-1 (显示 CTAG1B 抗体))

  5. The safety, the overall survival (OS), and the immunological responses based on an ELISPOT assay were determined to assess differences in patients who were HLA-A24 (显示 CD164 抗体)-positive [24(+)] and HLA-A24 (显示 CD164 抗体)-negative [24(-)].

  6. Here we define the nature and extent of the variation in 3,489 HLA-A, 4,356 HLA-B and 3,111 HLA-C alleles. The common alleles of human populations comprise 42 core alleles, which represent all selected polymorphism, and recombinants that have assorted this polymorphism

  7. It was shown that the HLA-A*34 allele is a risk factor for recurrent spontaneous abortion, while the HLA-A*24 and HLA-B*35 alleles are associated with protection, and no allele of the DRB1 (显示 RBM45 抗体) locus was associated with recurrent spontaneous abortion

  8. HLA-A alleles were not associated with predisposition to cutaneous leishmaniasis.

  9. a significant level of epitope-specific T cells could be detected ex vivo in peripheral blood mononuclear cells from active TB patients by an HLA-A*11:01 dextramer carrying the peptide Rv3130c194-204.

  10. In conclusion, our results confirm that the alleles HLA-A*02 and HLA-DRB1 (显示 HLA-DRB1 抗体)*07 are associated with the pathogenesis of vitiligo (显示 MITF 抗体) in the Brazilian population. We demonstrated that allele HLA-A*32 is associated with susceptibility to localized vitiligo (显示 MITF 抗体).

HLA-A 抗原简介

Antigen Summary

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described.

Alternative names and synonyms associated with HLA-A

  • major histocompatibility complex, class I, A (HLA-A) 抗体
  • HLAA 抗体

Protein level used designations for HLA-A

HLA class I histocompatibility antigen, A-1 alpha chain , MHC class I antigen HLA-A heavy chain , antigen presenting molecule , leukocyte antigen class I-A

GENE ID SPECIES
3105 Homo sapiens
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