Erythrocyte Ankyrin (ANK1) ELISA试剂盒产品概述

Full name:
Ankyrin 1, Erythrocytic ELISA试剂盒 (ANK1)
在www.antibodies-online.cn可供2 Ankyrin 1, Erythrocytic (ANK1) ELISA试剂盒的1不同的供货商。 再加上,我们可以发Erythrocyte Ankyrin 抗体 (66)和数多这个蛋白质的别的产品。 总共75 Erythrocyte Ankyrin产品已列进来了。
ANK, Ank-1, ANK1, CHANK1, nb, pale, SPH1, SPH2, wu:fa09h06, zgc:101835
list all ELISA KIts 基因 基因ID UniProt
ANK1 286 P16157
大鼠 ANK1 ANK1 306570  
ANK1 11733 Q02357



Erythrocyte Ankyrin (ANK1) ELISA试剂盒 by Reactivity

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Human Ankyrin 1, Erythrocytic (ANK1) interaction partners

  1. ANK1 is up-regulated 4-fold in Alzheimer disease microglia, but not in neurons or astrocytes from the same individuals.

  2. Two novel mutations in ANK1 (Y216X and E142X) are responsible for hereditary spherocytosis.

  3. These results suggest that sAnk1 interacts with SLN (显示 SLN ELISA试剂盒) both directly and in complex with SERCA1 (显示 ATP2A1 ELISA试剂盒) and reduces SLN's inhibitory effect on SERCA1 (显示 ATP2A1 ELISA试剂盒) activity.

  4. Mutational characteristics of ANK1 and SPTB (显示 SPTB ELISA试剂盒) genes in Korean hereditary spherocytosis have been described.

  5. Ankyrin-1 is induced to a greater extent than the embedded miRNA following DNA damage.

  6. analysis of a novel p.Q1772X ANK1 mutation in a Korean family with hereditary spherocytosis [case report of two family members]

  7. The study reports the refinement for a protein heterodimer complex using limited EPR (显示 EREG ELISA试剂盒) spectroscopic data and a rigid-body docking algorithm: a three-dimensional model for an ankyrin 1-BND3 (显示 SLC4A1 ELISA试剂盒) complex.

  8. A novel L1340P mutation in the ANK1 gene is associated with hereditary spherocytosis.

  9. Our analyses suggest that these DNA methylation (显示 HELLS ELISA试剂盒) changes may have a role in the onset of Alzheimer disease given that we observed them in presymptomatic subjects and that six of the validated genes connect to a known susceptibility gene network.

  10. We identified a differentially methylated region in the ankyrin 1 (ANK1) gene that was associated with neuropathology in the entorhinal cortex, a primary site of Alzheimer disease manifestation.

Mouse (Murine) Ankyrin 1, Erythrocytic (ANK1) interaction partners

  1. With increasing age (at 12-15 mo of age) extensor digitorum longus (EDL (显示 LIPG ELISA试剂盒)) skeletal muscles of sAnk1 KO mice develop prematurely large tubular aggregates.

  2. Study shows a direct interaction between beta-III spectrin (显示 SPTBN2 ELISA试剂盒) and erythroid ankyrin in the cerebellum and to demonstrate a critical role for beta-III spectrin (显示 SPTBN2 ELISA试剂盒) in maintaining ankyrin R throughout the Purkinje cell dendritic tree.

  3. Hema6 mutation of ankyrin-1 causes hereditary spherocytosis in mice through a mild reduction of protein expression.

  4. Suppression of hepcidin (显示 HAMP ELISA试剂盒) expression and iron overload mediate Salmonella susceptibility in ankyrin 1-mutated mice.

  5. We conclude that increased malaria resistance due to ankyrin-1 deficiency is caused by the intraerythrocytic death of P. chabaudi parasites.

  6. These results demonstrate that mammalian erythroblast enucleation does not depend on the membrane integrity generated by the ankyrin-band 3 (显示 SLC4A1 ELISA试剂盒) complex.

  7. The Ank1(E924X) strain provides a novel tool to study Ank1 and model HS.

  8. A spontaneous mutation, normoblastosis (Ank1nb) in mice provides an important animal model for human ankyrin-deficient anemias.

  9. Results support a role of obscurin (显示 OBSCN ELISA试剂盒) in mediating the subcellular localization of small ankyrin1 isoforms in striated (显示 NSDHL ELISA试剂盒) muscle cells.

  10. the organization of obscurin (显示 OBSCN ELISA试剂盒) at different locations in the sarcomere changes during muscle development and that this might affect the interaction with ank1.5.

Erythrocyte Ankyrin (ANK1) 抗原简介

Antigen Summary

Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified.

Alternative names and synonyms associated with Erythrocyte Ankyrin (ANK1)

  • ankyrin 1, erythrocytic (ANK1) Elisa Kit
  • ankyrin 1, erythrocytic (ank1) Elisa Kit
  • ankyrin 1, erythrocytic (Ank1) Elisa Kit
  • ankyrin 1, erythroid (Ank1) Elisa Kit
  • ANK Elisa Kit
  • Ank-1 Elisa Kit
  • ANK1 Elisa Kit
  • CHANK1 Elisa Kit
  • nb Elisa Kit
  • pale Elisa Kit
  • SPH1 Elisa Kit
  • SPH2 Elisa Kit
  • wu:fa09h06 Elisa Kit
  • zgc:101835 Elisa Kit

Protein level used designations for ANK1

ankyrin 1, erythrocytic , erythroid ankyrin , ankyrin-1-like , ANK-1 , ankyrin-1 , ankyrin-R , erythrocyte ankyrin , ankyrin 1, erythroid , normoblastic anemia

396311 Gallus gallus
449796 Danio rerio
613080 Xenopus (Silurana) tropicalis
736634 Pan troglodytes
100036926 Xenopus laevis
100055459 Equus caballus
100388861 Callithrix jacchus
100482591 Ailuropoda melanoleuca
100155697 Sus scrofa
286 Homo sapiens
353108 Bos taurus
306570 Rattus norvegicus
482842 Canis lupus familiaris
11733 Mus musculus
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