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Human BMP4 ELISA Kit for Sandwich ELISA - ABIN624950
Wozney: The bone morphogenetic protein family and osteogenesis. in Molecular reproduction and development 1992
Show all 17 Pubmed References
Human BMP4 ELISA Kit for Sandwich ELISA - ABIN624951
Wozney: The bone morphogenetic protein family and osteogenesis. in Molecular reproduction and development 1992
Show all 2 Pubmed References
Chicken BMP4 ELISA Kit for Sandwich ELISA - ABIN414154
Cheng, Leng, Wu, Zhang, Zhang, Xu, Cao, Li, Luan, Li: Expression analysis of bone morphogenetic protein 4 between fat and lean birds in adipose tissue and serum. in Domestic animal endocrinology 2016
Mouse (Murine) BMP4 ELISA Kit for Sandwich ELISA - ABIN1568654
Huang, Yao, Xie, Fu: 3D bioprinted extracellular matrix mimics facilitate directed differentiation of epithelial progenitors for sweat gland regeneration. in Acta biomaterialia 2016
Vrtn binds a bmp2b regulatory sequence and acts as a repressor to inhibit its zygotic transcription.
Study found that BMP-2 is negatively regulated by miR (显示 MYLIP ELISA试剂盒)-140 during early embryogenesis and bone development in zebra fi sh.
Data show that transcription of organizer-specific bone morphogenetic protein 2b (bmp2b) is directly down-regulated by Nodal and up-regulated by Wnt (显示 WNT2 ELISA试剂盒) signal.
Structures of Bmp2a (显示 BMP2 ELISA试剂盒), Bmp2b, Bmp4 and Bmp16 were found to be remarkably similar; with residues involved in receptor binding being highly conserved.
FGF signaling in establishment of the developmental hematopoietic stem cell niche occurs via inhibition of bmp4 transcription, and activation of bmp antagonists, nog2 and grem1a (显示 GREM1 ELISA试剂盒).
Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development.
BMP2b signaling in zebrafish embryos substantially decreases emergence of lymphatic endothelial cells.
Data show that BMP2B protein is expressed in a gradient as early as blastula stages.
we identify a previously unappreciated role for the Nodal-transcription factor FoxH1 in mediating cell responsiveness to Bmp further linking the control of these two pathways in the heart
The Bmp2b mutants and mosaic loss-of-function experiments reveal that BMP acts as a repressor of eye-field fate through inhibition of its key transcription factor Rx3, thereby protecting the future telencephalon from acquiring eye identity.
Data indicate that bone morphogenetic protein (BMP) signaling is essential for erythroid differentiation, and in the absence of BMP signaling, precursor cells adopt an endothelial cell (EC) fate.
Osr1 (显示 OSR1 ELISA试剂盒)/Osr2 normally repress bmp4 expression in the lateral plate mesoderm prior to respiratory specification.
The results suggest that DeltaNp63 is an essential gene in early epidermal specification under the control of BMP4.
PIAS (显示 PIAS1 ELISA试剂盒) proteins have differential ability to regulate signals from the growth factors activin (显示 Actbeta ELISA试剂盒), bone morphogenetic protein 4 (BMP4), and Wnt8 (显示 WNT8A ELISA试剂盒).
Data show that PV.1A undergoes combinatorial regulation during early Xenopus development as both the direct target of BMP-4 signaling and as the direct and indirect target of positive and negative regulatory factors.
BMP inhibition is sufficient for neural induction in vivo, and that in the absence of ventral BMPs, Spemann organizer signals are not required for brain formation.
Data suggest that the feedback inhibitors BAMBI (显示 BAMBI ELISA试剂盒), SMAD6 (显示 SMAD6 ELISA试剂盒), and SMAD7 (显示 SMAD7 ELISA试剂盒) expand the dynamic BMP4 signaling range essential for proper embryonic patterning and reduce interindividual phenotypic and molecular variability in Xenopus embryos.
limits homeobox (显示 PRRX1 ELISA试剂盒) gene expression in the organiser/non-organiser direction
X-epilectin expression is down-regulated by Noggin (显示 NOG ELISA试剂盒) and tBR and that this effect is inhibited by BMP4 over-expression
BMP4-dependent expression of Xenopus Grainyhead-like 1 (显示 GRHL1 ELISA试剂盒) has a critical role in epidermal differentiation
BMP4 signaling plays a role in the regulation of terminal differentiation of primary equine trophoblast cells via activation of the SMAD1 (显示 SMAD1 ELISA试剂盒)/5 pathway
Gene expression profiling showed that MuSK (显示 MUSK ELISA试剂盒) was required for the BMP4-induced expression of a subset of genes in myoblasts, including regulator of G protein signaling 4 (Rgs4 (显示 RGS4 ELISA试剂盒)).
BMP4 levels are increased dramatically in individuals with impaired glucose tolerance and type 2 diabetes.
The results suggest that selective RNA decay via TGF-beta (显示 TGFB1 ELISA试剂盒) and BMP4 signaling is critical for specifying the developmental fate of specific human embryonic cell lineages.
Expression of bone morphogenetic protein (BMP) 4, an upstream stimulator of SOX9, was upregulated by CG.
Study shows that BMP4 is overexpressed in hepatocellular carcinoma (HCC (显示 FAM126A ELISA试剂盒)) tissues and BMP4-induced ID2/CDKN1B (显示 CDKN1B ELISA试剂盒) signaling facilitates the proliferation of HCC (显示 FAM126A ELISA试剂盒).
Data suggest pituitary cells secrete factor (TSP1) that binds to and inhibits action of BMP2 and BMP4; von Willebrand type C domain of TSP1 is likely responsible for this BMP2/4-binding activity. These studies were initially conducted using cultured cells from ovine pituitary gland and mouse cell line; interactions were confirmed using recombinant human proteins. (TSP1 = thrombospondin-1; BMP = bone morphogenetic protein)
we demonstrate that expression of bone morphogenetic protein 4 (BMP-4) is universally upregulated in human colorectal cancer cells and tissues, resulting in activated BMP signaling
RUNX1T1 (显示 RUNX1T1 ELISA试剂盒) serves as a common angiogenic driver for vaculogenesis and functionality of endothelial lineage cells
Phosphorylated Smad1/5/8/9 specifically bound to the BREs of Smad8/9 gene. The present study reveals that Smad8/9 is a unique R-Smad regulated through the BMP pathway at the mRNA level.
Meta-analysis to assess the effect of BMP4 rs17563 polymorphism on nonsyndromic cleft lip with or without cleft palate (NSCL (显示 NHLH1 ELISA试剂盒)/P) suggests that the C allele of BMP4 rs17563 may be a risk factor for NSCL (显示 NHLH1 ELISA试剂盒)/P among Asians and Caucasians, and may be a protective factor for NSCL (显示 NHLH1 ELISA试剂盒)/P in Brazilian population.
differentiated cells exhibited contracting masses. These results suggest that BMP4-mediated somatic stem cell reprogramming may become an alternative approach for cell therapy
Bmp4 promotes a brown to white-like adipocyte shift.
results suggest that bone morphogenetic protein 4 promotes the generation of male germ cells from induced pluripotent stem (iPS (显示 SLC27A4 ELISA试剂盒)) cells
These results suggest how BMP4 regulates adipocyte recruitment in subcutaneous (SC) white adipose tissue, and thus promote its beneficial metabolic effects.
Expression of Bmp4 in the ureteric mesenchyme depends on HH signaling and Foxf1 (显示 FOXF1 ELISA试剂盒), and that exogenous BMP4 rescued cell proliferation and epithelial differentiation in ureters with abrogated HH signaling or FOXF1 (显示 FOXF1 ELISA试剂盒) function.
the effect of titanium (Ti) with nanotopography (Nano) on the endogenous expression of BMP-2 (显示 BMP2 ELISA试剂盒) and BMP-4 and the relevance of this process to the nanotopography-induced osteoblast differentiation.
These data indicate that Foxc1 (显示 FOXC1 ELISA试剂盒) expression is regulated by BMP4 and FOXC1 (显示 FOXC1 ELISA试剂盒) functions in the commitment of progenitor cells to the osteoblast fate and its expression is reduced when differentiation proceeds.
High BMP4 expression is associated with cystic ovarian disease.
Bone morphogenetic protein 4 and retinoic acid trigger bovine VASA homolog (显示 DDX4 ELISA试剂盒) expression in differentiating bovine induced pluripotent stem cells.
The BMP2/4 ligand and receptor system presides within bovine trophectoderm prior to uterine attachment. BMP4 negatively impacts CT1 (显示 SLC6A8 ELISA试剂盒) cell growth
BMP4 during maturation increased the proportion of Oct-4 (显示 POU5F1 ELISA试剂盒) positive cells in parthenogenic embryos. BMP4 is implicated in bovine oocytes maturation and embryo development.
analysis of polymorphic CA microsatellites in the third exon of the bovine BMP4 gene
concluded that a bone morphogenetic protein (BMP)-signaling system, consisting of BMP2, BMP4, type II and I receptors, is present in bovine antral follicles and plays a role in development and functioning of follicles rather than in oocyte maturation
Data report that BMP-7 (显示 BMP7 ELISA试剂盒) suppresses granulosa cell apoptosis by inhibiting the release of caspase-activated DNase (CAD (显示 DFFB ELISA试剂盒)) via a mechanism which does not appear to be associated with the mitochondrial pathway, whereas BMP-4 inhibits the release of CAD (显示 CAD ELISA试剂盒).
Heat shock protein 70 (显示 HSP70 ELISA试剂盒) enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein (显示 MGP ELISA试剂盒).
A microsatellite (ACn (显示 ACIN1 ELISA试剂盒)) was identified in the 3' UTR (显示 UTS2R ELISA试剂盒) of BMP4 gene.Prolificacy associated microsatellite (AC19 (显示 POLR1D ELISA试剂盒)) was detected in Indian goats.
paracrine signals from the embryo, represented by FGF4 (显示 FGF4 ELISA试剂盒) and BMP4, induce a response in the trophoblast prior to the extensive elongation.
The structure of porcine BMP4 gene is highly conservative with other mammalian BMP4 genes, but some differences may be present in the regulation of gene expression.
Altered shear stress stimulates upregulation of endothelial VCAM-1 (显示 VCAM1 ELISA试剂盒) and ICAM-1 (显示 ICAM1 ELISA试剂盒) in a BMP-4- and TGF-beta1 (显示 TGFB1 ELISA试剂盒)-dependent pathway.
The TM-induced characteristic changes in the expression pattern of Hoxa11 (显示 HOXA11 ELISA试剂盒) and Bmp4 on GDs (显示 PAEP ELISA试剂盒) 10 and/or 11 were not noted.
BMP4 is expressed peripherally in hypoblast and epiblast and in the mesoderm at the posterior pole of the embryonic disc.
Data show that BMP-2 (显示 BMP2 ELISA试剂盒), BMP-4, and BMP-7 (显示 BMP7 ELISA试剂盒), noggin (显示 NOG ELISA试剂盒), and chordin (显示 CHRD ELISA试剂盒) were colocalized in rimming osteoblasts, osteoclasts, and chondrocytes.
Both of the adenovirus-containing bone morphogenetic protein transduced MSCs expressed BMP4 mRNA and protein and underwent osteogenic differentiation.
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
, bone morphogenetic protein-4
, bone morphogenetic protein 4
, bone morphogenetic protein 4, isoform 3
, Bone morphogenetic protein 4
, bone morphogenetic protein 4-like
, bone morphogenetic protein 2
, bone morphogenetic protein 2B