anti-F-Box Protein 11 (FBXO11) 抗体产品概述

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anti-F-Box Protein 11 抗体 (FBXO11)
在www.antibodies-online.cn可供81 F-Box Protein 11 (FBXO11) 抗体的15不同的供货商。 再加上,我们可以发F-Box Protein 11 试剂盒 (12)F-Box Protein 11 蛋白 (9)和数多这个蛋白质的别的产品。 总共108 F-Box Protein 11产品已列进来了。
别名:
C80048, DKFZp459P2410, FBX11, Fbxo11, im:6906507, Jf, MGC84634, PRMT9, UBR6, Vit1, wu:fj83f06, zgc:153171
列出全部抗体 基因 基因ID UniProt
FBXO11 80204 Q86XK2
FBXO11 225055  
FBXO11 301674 Q7TSL3

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  1. Human Monoclonal FBXO11 Primary Antibody for IHC (p), ELISA - ABIN393772 : Guan, Lin, Hong, Fu, Zhou, Xu, Xu: [Expression of InnVit/FBXO11 in vitiligo and its role in tyrosinase export from endoplasmic reticulum]. in Zhonghua yi xue za zhi 2010 (PubMed)
    Show all 5 references for 393772

  2. Human Polyclonal FBXO11 Primary Antibody for IP, SimWes - ABIN252979 : Duan, Cermak, Pagan, Rossi, Martinengo, di Celle, Chapuy, Shipp, Chiarle, Pagano: FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas. in Nature 2012 (PubMed)
    Show all 3 references for 252979

  3. Amphibian Polyclonal FBXO11 Primary Antibody for ChIP, WB - ABIN4890506 : Lee, Pal, Tasaki, Roy, Jiang, An, Banerjee, Kwon: Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  4. Human Polyclonal FBXO11 Primary Antibody for IP, WB - ABIN252978 : Pagan, Marzio, Jones, Saraf, Jallepalli, Florens, Washburn, Pagano: Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing. in Nature cell biology 2014 (PubMed)

更多抗F-Box Protein 11的相互作用对抗体

Human F-Box Protein 11 (FBXO11) interaction partners

  1. FBXO11 is a direct target of miR (显示 MLXIP 抗体)-621 in breast cancer cells.

  2. UBR3/6 regulate cardiomyocyte Nav 1.5 channel protein levels via the ubiquitin-proteasome pathway.

  3. siRNA-mediated knockdown of FBXO11 facilitated HIF-1alpha (显示 HIF1A 抗体) expression in various cancer cells and HIF-1alpha (显示 HIF1A 抗体)-driven gene expressions, but the FBXO10 (显示 FBXO10 抗体) knockdown did not.

  4. Our results identify FBXO11 as a novel miR (显示 MLXIP 抗体)-21 target gene, and demonstrate that the oncogenic miRNA miR (显示 MLXIP 抗体)-21 decreases the expression of FBXO11, which normally acts as a tumor suppressor, and thereby promotes tumorigenesis.

  5. study defined eight additional recurrently mutated genes in SMZL; these genes are CREBBP (显示 CREBBP 抗体), CBFA2T3 (显示 CBFA2T3 抗体), AMOTL1 (显示 AMOTL1 抗体), FAT4 (显示 FAT4 抗体), FBXO11, PLA2G4D, TRRAP (显示 TRRAP 抗体) and USH2A (显示 USH2A 抗体).

  6. The PKD1 (显示 PKD1 抗体)-FBXO11-SNAIL (显示 SNAI1 抗体) axis is a mechanism of posttranslational regulation of epithelial-mesenchymal transition and cancer metastasis.

  7. TGF-beta signaling promotes exit from the cell cycle and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2.

  8. The functional interaction between FBXO11 and CDT2 is evolutionary conserved from worms to humans and plays an important role in regulating the timing of cell-cycle exit.

  9. Migration of epithelial cells is stimulated by CRL1 (显示 IL27RA 抗体)(FBXO11)-mediated downregulation of Cdt2 (显示 DTL 抗体) and the consequent stabilization of Set8 (显示 SETD8 抗体).

  10. A molecular mechanism controlling BCL6 (显示 BCL6 抗体) stability--mutations and deletions in FBXO11 contribute to lymphomagenesis through BCL6 (显示 BCL6 抗体) stabilization

Mouse (Murine) F-Box Protein 11 (FBXO11) interaction partners

  1. FBXO11 inactivation was associated with the development of lymphoproliferative disorders in mice.

  2. FBXO11 regulates the TGF-beta (显示 TGFB1 抗体) pathway in the embryonic lung via cross-talk with p53 (显示 TP53 抗体).

  3. FBXO11 is one of the first molecules to be identified, contributing to the genetic aetiology of otitis media

  4. Relationship between dilation of endoplasmic reticulum and decreased levels of the FBXO11 gene in vitiligo (显示 MITF 抗体) melanocytes.

F-Box Protein 11 (FBXO11) 抗原简介

Antigen Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It can function as an arginine methyltransferase that symmetrically dimethylates arginine residues, and it acts as an adaptor protein to mediate the neddylation of p53, which leads to the suppression of p53 function. This gene is known to be down-regulated in melanocytes from patients with vitiligo, a skin disorder that results in depigmentation. Polymorphisms in this gene are associated with chronic otitis media with effusion and recurrent otitis media (COME/ROM), a hearing loss disorder, and the knockout of the homologous mouse gene results in the deaf mouse mutant Jeff (Jf), a single gene model of otitis media. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with F-Box Protein 11 (FBXO11)

  • F-box protein 11 (FBXO11) 抗体
  • F-box protein 11a (fbxo11a) 抗体
  • F-box protein 11 (fbxo11) 抗体
  • F-box only protein 11 (CpipJ_CPIJ009919) 抗体
  • F-box only protein 11 (CpipJ_CPIJ017549) 抗体
  • F-box only protein 11 (Bm1_52225) 抗体
  • F-box only protein 11 (LOAG_02072) 抗体
  • F-box protein 11 (Fbxo11) 抗体
  • F-box only protein 11 (LOC100351392) 抗体
  • C80048 抗体
  • DKFZp459P2410 抗体
  • FBX11 抗体
  • Fbxo11 抗体
  • im:6906507 抗体
  • Jf 抗体
  • MGC84634 抗体
  • PRMT9 抗体
  • UBR6 抗体
  • Vit1 抗体
  • wu:fj83f06 抗体
  • zgc:153171 抗体

Protein level used designations for anti-F-Box Protein 11 (FBXO11) 抗体

F-box only protein 11 , F-box protein 11 , fj83f06 , F-box only protein 11-like , f-box only protein 11-like , protein arginine N-methyltransferase 9 , ubiquitin protein ligase E3 component n-recognin 6 , vitiligo-associated protein 1 , vitiligo-associated protein VIT-1 , GENA 104 , jeff

GENE ID SPECIES
508172 Bos taurus
777607 Danio rerio
421289 Gallus gallus
100624629 Sus scrofa
446439 Xenopus laevis
459219 Pan troglodytes
481363 Canis lupus familiaris
6042345 Culex quinquefasciatus
6051322 Culex quinquefasciatus
6105329 Brugia malayi
9939454 Loa loa
100036658 Xenopus (Silurana) tropicalis
100115478 Nasonia vitripennis
100174158 Pongo abelii
100414214 Callithrix jacchus
100472231 Ailuropoda melanoleuca
100541804 Meleagris gallopavo
100562601 Anolis carolinensis
100581026 Nomascus leucogenys
100351392 Oryctolagus cuniculus
80204 Homo sapiens
225055 Mus musculus
301674 Rattus norvegicus
101107682 Ovis aries
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