anti-CLIC5 (CLIC5) 抗体产品概述

Full name:
anti-Chloride Intracellular Channel 5 抗体 (CLIC5)
在www.antibodies-online.cn可供46 Chloride Intracellular Channel 5 (CLIC5) 抗体的11不同的供货商。 再加上,我们可以发CLIC5 蛋白 (7)CLIC5 试剂盒 (1)和数多这个蛋白质的别的产品。 总共60 CLIC5产品已列进来了。
别名:
5730531E12Rik, B330005L24, CLIC5, Gm322, im:6907594, jbg, MGC68985, MST130, MSTP130, zgc:77538, zgc:101827

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引用最多的anti-CLIC5 抗体

  1. Human Polyclonal CLIC5 Primary Antibody for EIA, IHC (p) - ABIN359754 : Berryman, Bruno, Price, Edwards: CLIC-5A functions as a chloride channel in vitro and associates with the cortical actin cytoskeleton in vitro and in vivo. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for 359754

  2. Cow (Bovine) Polyclonal CLIC5 Primary Antibody for IHC, WB - ABIN2776218 : Li, Yin, Ni, Liu, Zhang, Du: Chloride intracellular channel 5 modulates adipocyte accumulation in skeletal muscle by inhibiting preadipocyte differentiation. in Journal of cellular biochemistry 2010 (PubMed)
    Show all 2 references for 2776218

  3. Human Monoclonal CLIC5 Primary Antibody for IF, IHC (p) - ABIN526971 : Wegner, Al-Momany, Kulak, Kozlowski, Obeidat, Jahroudi, Paes, Berryman, Ballermann: CLIC5A, a component of the ezrin-podocalyxin complex in glomeruli, is a determinant of podocyte integrity. in American journal of physiology. Renal physiology 2010 (PubMed)

更多抗CLIC5的相互作用对抗体

Human Chloride Intracellular Channel 5 (CLIC5) interaction partners

  1. loss of ETV6 (显示 ETV6 抗体) leads to significant overexpression of CLIC5, which in turn leads to decreased lysosome-mediated apoptosis. Our data suggest that heightened CLIC5 activity could promote a permissive environment for oxidative stress-induced (显示 SQSTM1 抗体) DNA damage accumulation, and thereby contribute to leukemogenesis.

  2. EZR (显示 EZR 抗体), CLIC5 and PODXL (显示 PODXL 抗体) are overexpressed in hepatocellular carcinoma and may have a role in cell migration and invasiveness

  3. The mechanism of CLIC5A action involves clustered plasma membrane phosphatidylinositol 4,5-bisphosphate accumulation, in turn facilitating ezrin activation and actin-dependent cell surface remodeling.

  4. CLIC5 is a novel gene involved in progressive hearing impairment, vestibular and possibly mild renal dysfunction.

  5. CLIC5A colocalizes with ezrin (显示 EZR 抗体) and podocalyxin (显示 PODXL 抗体) in podocytes and is required for the development/maintenance of the proper glomerular endothelial cell and podocyte architecture.

  6. association with Golgi apparatus AKAP350 (显示 AKAP9 抗体)

  7. CLIC-5A has a role as a chloride channel in vitro and binds to cortical actin cytoskeleton

  8. CLIC5 was demonstrated in cultured lymphoblasts.

  9. Data showed that CLIC1 and CLIC5, but not CLIC4, were strongly and reversibly inhibited (or inactivated) by F-actin.

Pig (Porcine) Chloride Intracellular Channel 5 (CLIC5) interaction partners

  1. results suggest that CLIC5 might be a crucial regulator of adipose accumulation in skeletal muscle of pigs

Cow (Bovine) Chloride Intracellular Channel 5 (CLIC5) interaction partners

  1. CLIC5A colocalizes with ezrin (显示 EZR 抗体) and podocalyxin (显示 PODXL 抗体) in podocytes and is required for the development/maintenance of the proper glomerular endothelial cell and podocyte architecture.

Mouse (Murine) Chloride Intracellular Channel 5 (CLIC5) interaction partners

  1. The findings indicate that CLIC4 (显示 CLIC4 抗体)/CLIC5A-mediated ERM (显示 ETV5 抗体) activation is required for maintenance of the glomerular capillary architecture.

  2. Augmented hypertension-induced glomerular capillary injury in mice lacking CLIC5 results from abrogation of Rac1-dependent Pak and ezrin activation, perhaps reducing the tensile strength of the podocyte actin cytoskeleton.

  3. The mechanism of CLIC5A action involves clustered plasma membrane phosphatidylinositol 4,5-bisphosphate accumulation, in turn facilitating ezrin activation and actin-dependent cell surface remodeling.

  4. Biochemical assays showed interaction of CLIC5 with ERM (显示 ETV5 抗体) proteins, TPRN (显示 TPRN 抗体), and possibly myosin VI (MYO6 (显示 MYO6 抗体)). In addition, CLIC5 and RDX (显示 RDX 抗体) failed to localize normally in fused stereocilia of MYO6 (显示 MYO6 抗体) mutant mice

  5. miR (显示 MLXIP 抗体)-96 and miR (显示 MLXIP 抗体)-182 regulate the in vivo expression of CLIC5 in mouse inner ear hair cells

  6. Study identifies CLIC5 as a new component that is enriched in and necessary for foot process integrity and podocyte function in vivo.

  7. CLIC5 disrupts proliferation of C2C12 cells and is involved in the differentiation of myoblasts by enhancing the protein expression level of MyHC (显示 MYH13 抗体), myogenin (显示 MYOG 抗体) and desmin (显示 DES 抗体).

  8. Clic5 mutant mice are resistant to diet-induced obesity.

  9. CLIC5A colocalizes with ezrin (显示 EZR 抗体) and podocalyxin (显示 PODXL 抗体) in podocytes and is required for the development/maintenance of the proper glomerular endothelial cell and podocyte architecture.

  10. CLIC5 associates with radixin in hair cell stereocilia and may help form or stabilize connections between the plasma membrane and the filamentous actin core.

CLIC5 抗原简介

Antigen Summary

This gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The encoded protein associates with actin-based cytoskeletal structures and may play a role in multiple processes including hair cell stereocilia formation, myoblast proliferation and glomerular podocyte and endothelial cell maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with CLIC5

  • chloride intracellular channel 5 (clic5) 抗体
  • chloride intracellular channel 5 (CLIC5) 抗体
  • chloride intracellular channel 5a (clic5a) 抗体
  • chloride intracellular channel 5 (Clic5) 抗体
  • chloride intracellular channel 5b (clic5b) 抗体
  • 5730531E12Rik 抗体
  • B330005L24 抗体
  • CLIC5 抗体
  • Gm322 抗体
  • im:6907594 抗体
  • jbg 抗体
  • MGC68985 抗体
  • MST130 抗体
  • MSTP130 抗体
  • zgc:77538 抗体
  • zgc:101827 抗体

Protein level used designations for CLIC5

chloride intracellular channel 5 , chloride intracellular channel protein 6 , chloride intracellular channel protein 5-like , chloride intracellular channel protein 5 , chloride channel protein p64 , chlorine channel protein p64

GENE ID SPECIES
380025 Xenopus laevis
462739 Pan troglodytes
492513 Danio rerio
703565 Macaca mulatta
100055661 Equus caballus
100407287 Callithrix jacchus
100453932 Pongo abelii
100470286 Ailuropoda melanoleuca
100587743 Nomascus leucogenys
422054 Gallus gallus
53405 Homo sapiens
481822 Canis lupus familiaris
100154589 Sus scrofa
281696 Bos taurus
224796 Mus musculus
94272 Rattus norvegicus
734242 Xenopus laevis
405833 Danio rerio
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