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The findings suggest that, in contrast with previous models, the ligand-binding site of integrin alphaVbeta3 (显示 ITGAV ELISA试剂盒), binds to the constant region (helices A and B) of the EC2 (显示 TCF15 ELISA试剂盒) domain of CD9 (显示 CD9 ELISA试剂盒), CD81 (显示 CD81 ELISA试剂盒), and CD151 (显示 CD151 ELISA试剂盒) antigens.
Data suggest that CD9 (显示 CD9 ELISA试剂盒) should be further evaluated as a target for glioblastoma treatment.
Collectively, using tetraspanin CD9 (显示 CD9 ELISA试剂盒) in tandem with E-cadherin (显示 CDH1 ELISA试剂盒) as a biomarker in renal cell carcinoma will help to not only distinguish between types, but also predict the metastatic potential of RCC (显示 XRCC1 ELISA试剂盒).
Data indicate that CD9 (显示 CD9 ELISA试剂盒) is implicated in BCC invasiveness and metastases by cellular mechanisms that involve specific CD9 (显示 CD9 ELISA试剂盒)+ plasma membrane protrusions of BCCs.
CD9 (显示 CD9 ELISA试剂盒)-enriched microdomains negatively regulate LPS (显示 IRF6 ELISA试剂盒)-induced receptor formation by preventing CD14 (显示 NDUFA2 ELISA试剂盒) from accumulating into lipid rafts. [Review]
Results indicate that CD9 (显示 CD9 ELISA试剂盒) downregulation promoted pancreatic cancer cell proliferation and migration through at least in part, enhancing the cell surface expression of EGFR (显示 EGFR ELISA试剂盒).
CD9 (显示 CD9 ELISA试剂盒) expression is upregulated and its expression is correlated with tumor stage and lymph node metastasis in esophageal squamous cell carcinoma patients
Although the current findings did not prove any hypothesis, the indispensable role of CD9 (显示 CD9 ELISA试剂盒) in fertilization process was not excluded and the precise role of CD9 (显示 CD9 ELISA试剂盒) remains unexplained. [review]
CD9 (显示 CD9 ELISA试剂盒) plays a role in the dysmegakaryopoiesis that occurs in primary myelofibrosis.
High CD9 (显示 CD9 ELISA试剂盒) is associated with B acute lymphoblastic leukemia.
Mice lacking RXRalpha (显示 RXRA ELISA试剂盒) in myeloid cells exhibit reduced levels of CCL6 (显示 CCL6 ELISA试剂盒) and CCL9 (显示 Ccl9 ELISA试剂盒), impaired recruitment of leukocytes to sites of inflammation, and lower susceptibility to sepsis.
enhanced expression in intestinal epithelium following immunostimulation with LPS (显示 TLR4 ELISA试剂盒) or pro-inflammatory cytokines
the injury-induced expression of C10 at the mRNA and protein level
c10 promotes fibrosis by recruiting macrophages in the inflammatory response to bleomycin in the lung
CCL6 (显示 CCL6 ELISA试剂盒) gene activation and production induced by SCF (显示 KITLG ELISA试剂盒) in the presence or absence of rather specific inhibitors for certain pathways demonstrated that the MEK (显示 MDK ELISA试剂盒)/MAPK (显示 MAPK1 ELISA试剂盒) pathway but not the PI-3K pathway was crucial for the SCF (显示 KITLG ELISA试剂盒)-induced CCL6 (显示 CCL6 ELISA试剂盒) gene activation.
the chemokines CCL6 (显示 CCL6 ELISA试剂盒) and CCL9 (显示 Ccl9 ELISA试剂盒) as genes prominently induced by the type I IFNs and ICSBP (显示 IRF8 ELISA试剂盒)
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis.
ATP-binding cassette sub-family C ( CFTR/MRP) member 1a
, ATP-binding cassette sub-family C member 1
, ATP-binding cassette, sub-family C (CFTR/MRP), member 1
, LTC4 transporter
, leukotriene C(4) transporter
, multidrug resistance protein 1
, multidrug resistance-associated protein 1
, multiple drug resistance-associated protein
, 5H9 antigen
, BA-2/p24 antigen
, CD9 antigen
, CD9 antigen (p24)
, cell growth-inhibiting gene 2 protein
, leukocyte antigen MIC3
, motility related protein-1
, C-C motif chemokine 6
, CC chemokine C10
, small inducible cytokine A6
, small-inducible cytokine A6