电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

RAN 抗体

(RAN, Member RAS Oncogene Family (RAN))
RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor. Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy). RAN coactivation of the AR diminishes with polyglutamine expansion within the AR, and this weak coactivation may lead to partial androgen insensitivity during the development of Kennedy's disease. [provided by RefSeq, Jul 2008].
RAN 抗体  (AA 1-216) RAN 抗体  (AA 1-216) RAN 抗体 (AA 1-216) (ABIN5542382)

RAN 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8D1A6 unconjugated

RAN 抗体  (N-Term) RAN 抗体  (N-Term) RAN 抗体 (N-Term) (ABIN185256)

Verified RAN 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

RAN 抗体  (AA 2-216) RAN 抗体  (AA 2-216) RAN 抗体 (AA 2-216) (ABIN5518950)

RAN 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

RAN 抗体 by Grade

Find RAN 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

RAN 抗体 by 适用

Find RAN 抗体 for a variety of species such as anti-Human RAN, anti-Rat RAN, anti-Mouse RAN. The species listed below are among those available. Click on a link to go to the corresponding products.

RAN 抗体 by 应用范围

Find RAN 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

RAN 抗体 by 抗体来源

Find RAN 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

RAN 抗体 by 抗原表位

Find RAN 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

RAN 抗体 by 克隆形成能力

Find available monoclonal or polyclonal RAN 抗体. Click on a link to go to the corresponding products.

RAN 抗体 by 克隆

Find RAN 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

RAN 抗体 by 标记

Find RAN 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular RAN 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (10)
Cat. No. ABIN5542382
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN185256
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (6)
Cat. No. ABIN5518950
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (6)
Cat. No. ABIN3032431
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IHC (p), ICC
Validations
  • (4)
Cat. No. ABIN467626
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN3021203
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (5)
Cat. No. ABIN390647
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (5)
Cat. No. ABIN3032430
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN571291
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7154577
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN562575
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7255065
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6264629
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN652226
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7003146
Quantity 20 μL
Datasheet Datasheet

Latest Publications for our RAN 抗体

Zhang, Yang, Cao, Xu, Li, Chen, Gao, Xin, Zhou, Zhou, Yang, Sheng, Zeng: "MiR-203 suppresses tumor growth and invasion and down-regulates MiR-21 expression through repressing Ran in esophageal cancer." in: Cancer letters, Vol. 342, Issue 1, pp. 121-9, (2013) (PubMed).

Xia, Dohi, Martin, Raskett, Liu, Altieri: "Essential role of the small GTPase Ran in postnatal pancreatic islet development." in: PLoS ONE, Vol. 6, Issue 11, pp. e27879, (2011) (PubMed).

Ly, Wang, Pereira, Rojas, Peng, Feng, Cerione, Wilson: "Activation of the Ran GTPase is subject to growth factor regulation and can give rise to cellular transformation." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5815-26, (2010) (PubMed).

Simula, Cannizzaro, Canzonieri, Pavan, Maiero, Toffoli, De Re: "PPAR signaling pathway and cancer-related proteins are involved in celiac disease-associated tissue damage." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 5-6, pp. 199-209, (2010) (PubMed).

Nilsen, Rosendal, Sørensen, Wesche, Olsnes, Wiedłocha: "A nuclear export sequence located on a beta-strand in fibroblast growth factor-1." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26245-56, (2007) (PubMed).

Ramos, Rafikova, Melikov, Chernomordik: "Transmembrane proteins are not required for early stages of nuclear envelope assembly." in: The Biochemical journal, Vol. 400, Issue 3, pp. 393-400, (2006) (PubMed).

Nemergut, Lindsay, Brownawell, Macara: "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 17385-8, (2002) (PubMed).

Schwoebel, Ho, Moore: "The mechanism of inhibition of Ran-dependent nuclear transport by cellular ATP depletion." in: The Journal of cell biology, Vol. 157, Issue 6, pp. 963-74, (2002) (PubMed).

Faleiro, Lazebnik: "Caspases disrupt the nuclear-cytoplasmic barrier." in: The Journal of cell biology, Vol. 151, Issue 5, pp. 951-9, (2000) (PubMed).

Iborra, Jackson, Cook: "The path of RNA through nuclear pores: apparent entry from the sides into specialized pores." in: Journal of cell science, Vol. 113 Pt 2, pp. 291-302, (2000) (PubMed).

Aliases for RAN 抗体

RAN, member RAS oncogene family (RAN) 抗体
RAN, member RAS oncogene family (Ran) 抗体
RAN, member RAS oncogene family S homeolog (ran.S) 抗体
RAN, member RAS oncogene family (ran) 抗体
CG1404 gene product from transcript CG1404-RC (Ran) 抗体
AAF30287 抗体
ARA24 抗体
ara24 抗体
CG1404 抗体
Dmel\CG1404 抗体
dran 抗体
fc16b04 抗体
Gsp1 抗体
gsp1 抗体
l(1)G0075 抗体
ran 抗体
RAN 抗体
Ran 抗体
ran-1 抗体
ran10A 抗体
RANP1 抗体
TC4 抗体
tc4 抗体
wu:fc16b04 抗体
You are here:
客服