Chemokine (C-C Motif) Ligand 13 (CCL13) ELISA试剂盒产品概述

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别名:
CKb10, Mcp-4, Mcp4, MMCP-4, MMCP-4A, MMCP-4B, NCC-1, NCC1, SCYA13, SCYL1
list all ELISA KIts 基因 基因ID UniProt
CCL13 6357 Q99616
CCL13 17227 P21812
CCL13    

Chemokine (C-C Motif) Ligand 13 (CCL13) ELISA试剂盒 by Reactivity

适于 Chemokine (C-C Motif) Ligand 13 相互作用对的更多 ELISA 试剂盒

Human Chemokine (C-C Motif) Ligand 13 (CCL13) interaction partners

  1. CCL13 expression is significantly upregulated in human masticatory mucosa during wound healing

  2. The reduction of circulating levels of MCP-4, eotaxin-3 (显示 CCL26 ELISA试剂盒), and MIP-1beta (显示 CCL4 ELISA试剂盒) could be one of the mechanisms by which bariatric surgery contributes to the reduction of cardiovascular risk in these patients.

  3. CCL13 levels in serum and synovial fluid may serve as a biomarker for the progression of osteoarthritis.

  4. identified 13 ADCC-activated genes. Six gene expression assays including 8 of the 13 genes (CCL3 (显示 CCL3 ELISA试剂盒), CCL4/CCL4L1 (显示 CCL4 ELISA试剂盒)/CCL4L2, CD160 (显示 CD160 ELISA试剂盒), IFNG (显示 IFNG ELISA试剂盒), NR4A3 (显示 NR4A3 ELISA试剂盒) and XCL1 (显示 XCL1 ELISA试剂盒)/XCL2 (显示 XCL2 ELISA试剂盒)) were analyzed in 127 kidney biopsies

  5. CCL13 is an antimicrobial protein with bacteriocidal activity against E. coli.

  6. Data suggest that CCL13 binds to several chemokine (显示 CCL1 ELISA试剂盒) receptors (CCR1, CCR2 (显示 CCR2 ELISA试剂盒), and CCR3 (显示 CCR3 ELISA试剂盒)), allowing CCL13 to elicit different effects on target cells of immune system. CCL13 is involved in pathology of chronic inflammatory/autoimmune diseases. [REVIEW]

  7. MCP-4 and hsCRP may be the markers linking chronic inflammation in obesity and periodontal disease.

  8. E(2) has adverse effects on the pathogenesis of RA as a result of unregulated cell death, increased TNF-alpha (显示 TNF ELISA试剂盒)-induced MMP-3 (显示 MMP3 ELISA试剂盒) production, and CCL13 overproduction, subsequently resulting in the disease progression of RA.

  9. Data show that, for the small macrophages in COPD (显示 ARCN1 ELISA试剂盒), increased transcript and protein levels for CCL2 (显示 CCL2 ELISA试剂盒), CCL7 (显示 CCL7 ELISA试剂盒), CCL13 and CCL22 (显示 CCL22 ELISA试剂盒) with a more than 100-fold increase for CCL13 mRNA.

  10. Findings suggest that the pro-atherogenic effects of CCR2 (显示 CCR2 ELISA试剂盒) may not be restricted to interaction with MCP-1 (显示 CCL2 ELISA试剂盒), but could also involve activation by MCP-4, being an inflammatory link between platelet and monocyte activation.

Mouse (Murine) Chemokine (C-C Motif) Ligand 13 (CCL13) interaction partners

  1. deletion of the gene encoding MMCP-4 (Mcpt4), markedly reduced late, but not early, infarct size by suppressing IGF-1 (显示 IGF1 ELISA试剂盒) degradation and, consequently, diminished cardiac dysfunction and adverse structural remodeling

  2. Data indicate that a second-degree burn injury can initiate an immediate novel zonal degranulation of mast cell throughout all skin layers and a disruption of the epidermal tight junctions dependent on the nonredundant presence of mMCP4 and mMCP5 (显示 CMA1 ELISA试剂盒).

  3. these results support the conclusion that mast cells can contribute to the initial lung injury induced by bleomycin through release of the MCPT4 chymase (显示 CMA1 ELISA试剂盒).

  4. Mast cell chymase (显示 CMA1 ELISA试剂盒) degrades the alarmins heat shock protein 70 (显示 HSP70 ELISA试剂盒), biglycan (显示 BGN ELISA试剂盒), HMGB1 (显示 HMGB1 ELISA试剂盒), and interleukin-33 (IL-33 (显示 IL33 ELISA试剂盒)) and limits danger-induced inflammation.

  5. Data from Mcp-4 (mast cell protease 4) knockout mice suggest Mcp-4 plays a pivotal role in the dynamic (in vivo and in vitro) conversion of systemic Big-endothelin-1 (显示 EDN1 ELISA试剂盒) to endothelin-1 (显示 EDN1 ELISA试剂盒) (1-31).

  6. MCs (显示 SMCP ELISA试剂盒) exert protective functions after trauma, at least in part via mMCP-4, by suppressing exacerbated inflammation via their proteases.

  7. The effects of interactions between mMCP-4 and TNF (显示 TNF ELISA试剂盒) in vivo by analyzing the features of a classic model of polymicrobial sepsis, were assessed.

  8. mMCP-4 plays two different roles in the pathogenesis of experimental BP, by both activating MMP-9 (显示 MMP9 ELISA试剂盒) and by cleaving BP180 (显示 COL17A1 ELISA试剂盒), leading to injury of the hemidesmosomes and extracellular matrix of the basement membrane zone.

  9. mMCP-4-deficient mice but not to mMCP-5 (显示 CMA1 ELISA试剂盒)-deficient mice revealing nonredundant actions for these two MC proteases in a model of innate inflammatory injury with remodeling.

  10. MCP-4 contributes locally to the aggravation of glomerulonephritis by mediating a variety of proinflammatory effects.

Chemokine (C-C Motif) Ligand 13 (CCL13) 抗原简介

Antigen Summary

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis.

Alternative names and synonyms associated with Chemokine (C-C Motif) Ligand 13 (CCL13)

  • chemokine (C-C motif) ligand 13 (CCL13) Elisa Kit
  • mast cell protease 4 (Mcpt4) Elisa Kit
  • CKb10 Elisa Kit
  • Mcp-4 Elisa Kit
  • Mcp4 Elisa Kit
  • MMCP-4 Elisa Kit
  • MMCP-4A Elisa Kit
  • MMCP-4B Elisa Kit
  • NCC-1 Elisa Kit
  • NCC1 Elisa Kit
  • SCYA13 Elisa Kit
  • SCYL1 Elisa Kit

Protein level used designations for CCL13

C-C motif chemokine 13 , CK-beta-10 , monocyte chemoattractant protein 4 , monocyte chemotactic protein 4 , new CC chemokine 1 , small inducible cytokine subfamily A (Cys-Cys), member 13 , small-inducible cytokine A13 , monocyte chemotactic protein-4 , MSMCP , myonase , serosal mast cell protease

GENE ID SPECIES
6357 Homo sapiens
445451 Canis lupus familiaris
17227 Mus musculus
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