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抗Rat (Rattus) 抗体:
Human Polyclonal HOPX Primary Antibody for FACS, WB - ABIN655402
Kovárová, Plachy, Kosla, Trejbalová, ?ermák, Hejnar: Downregulation of HOPX controls metastatic behavior in sarcoma cells and identifies genes associated with metastasis. in Molecular cancer research : MCR 2013
Human Polyclonal HOPX Primary Antibody for ICC, IF - ABIN4319670
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
HOPX has a role in the pathogenesis of skin cancers and skin diseases.
these data indicate that the disruption of the PrP(C (显示 PRNP 抗体))-HOP (显示 STIP1 抗体) complex could be a potential therapeutic target for modulating the migratory and invasive cellular properties that lead to metastatic Colorectal cancer (CRC (显示 CALR 抗体)).
HOPX promoter methylation is not only frequent and cancer-specific but also associated with aggressive phenotype in breast cancer.
Computational results identified HOPX gene as a new potential driver for ovarian carcinogenesis.
The results suggest that HOPX may contribute to pathogenesis or manifestation of hypertrophic cardiomyopathy as a modifier gene.
Data show that binding of heat shock proteins Hsp70 (显示 HSP70 抗体) and Hsp90 (显示 HSP90 抗体) requires prior binding of Hop (显示 STIP1 抗体) protein to Hsp90 (显示 HSP90 抗体).
HOPX is methylated and exerts tumour-suppressive function through Ras-induced senescence in human lung cancer.
GATA6 (显示 GATA6 抗体) and HOPX are critical nodes in a lineage-selective pathway that directly links effectors of airway epithelial specification to the inhibition of metastasis in the lung ADC (显示 ADC 抗体) subtype.
HOPX-beta promoter methylation is a frequent and cancer-specific event in CRC (显示 CALR 抗体) progression.
Knockdown of Hop (显示 STIP1 抗体) caused a decrease in the level of RhoC GTPase (显示 RHOC 抗体), and significantly inhibited pseudopodia formation in Hs578T cells. Our data suggest that Hop (显示 STIP1 抗体) regulates directional cell migration by multiple unknown mechanisms.
Analysis of the hematopoietic stem/progenitor cell pool in Hopx-/- mice demonstrated significantly reduced cell frequencies and impaired engraftment in competitive repopulation assays, thus providing functional validation of this positional candidate gene
Type I alveolar cells expressing Hopx manifest plasticity to regenerate type II alveolar cells in the lung.
Peripherally Induced Tolerance Depends on Peripheral Regulatory T Cells That Require Hopx To Inhibit Intrinsic IL-2 (显示 IL2 抗体) Expression.
Hopx integrates Bmp and Wnt (显示 WNT2 抗体) signaling by physically interacting with activated Smads and repressing Wnt (显示 WNT2 抗体) genes.
Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells.
HOPX/Hopx expression is reduced in multiple examples of human and murine cardiac hypertrophy and failure.
Hopx regulates the expression of genes involved in regulation of apoptosis and survival and makes them refractory to Fas (显示 FAS 抗体)-induced apoptosis.
Hopx is required for the function of regulatory T cells induced by DCs and the promotion of DC-mediated T cell unresponsiveness in vivo.
Hdac2 (显示 HDAC2 抗体), Hopx, and Gata4 (显示 GATA4 抗体) coordinately regulate cardiac myocyte proliferation during embryonic development.
data show that Hop (显示 STIP1 抗体) can inhibit serum response factor-dependent transcriptional activation by recruiting histone deacetylase (HDAC (显示 HDAC1 抗体)) activity and can form a complex that includes HDAC2 (显示 HDAC2 抗体)
The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene.
, homeodomain-only protein
, Homeodomain-only protein
, lung cancer-associated Y protein
, not expressed in choriocarcinoma clone 1
, not expressed in choriocarcinoma protein 1
, odd homeobox 1 protein
, odd homeobox protein 1
, homeobox only domain
, homeobox-only protein
, homeodomain only protein
, odd homeobox 1
, global ischemia induced protein GIIG15B
, global ischemia-induced gene 15B protein
, global ischemia-induced protein 15B