anti-MED23 (MED23) 抗体产品概述

Full name:
anti-Mediator Complex Subunit 23 抗体 (MED23)
在www.antibodies-online.cn可供54 Mediator Complex Subunit 23 (MED23) 抗体的17不同的供货商。 再加上,我们可以发MED23 试剂盒 (11)MED23 蛋白 (4)和数多这个蛋白质的别的产品。 总共75 MED23产品已列进来了。
别名:
130kDa, 3000002A17Rik, ARC130, CG3695, crsp3, CRSP130, CRSP133, Dmel\\CG3695, DRIP130, dSUR2, dTRAP150beta, ESTM7, Gal11/SUR2, MED23, mKIAA1216, MRT18, si:ch211-272f15.2, SUR-2, Sur2, Trap150, Trap150beta, X83317, zgc:91979
列出全部抗体 基因 基因ID UniProt
MED23 9439 Q9ULK4
MED23 70208 Q80YQ2
MED23 309565  

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抗Human MED23 抗体:

抗Mouse (Murine) MED23 抗体:

抗Rat (Rattus) MED23 抗体:

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引用最多的anti-MED23 抗体

  1. Human Polyclonal MED23 Primary Antibody for ChIP, IP - ABIN152372 : Meyer, Donner, Knuesel, York, Espinosa, Taatjes: Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3. in The EMBO journal 2008 (PubMed)
    Show all 5 references for 152372

  2. Human Polyclonal MED23 Primary Antibody for IP - ABIN152373 : Terada, Saitoh, Ohno, Komada, Saitoh, Peles, Ohno: Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves. in Molecular and cellular biology 2011 (PubMed)
    Show all 4 references for 152373

  3. Human Monoclonal MED23 Primary Antibody for WB - ABIN967286 : Blobel: CREB-binding protein and p300: molecular integrators of hematopoietic transcription. in Blood 2000 (PubMed)
    Show all 3 references for 967286

  4. Human Polyclonal MED23 Primary Antibody for IF, IHC - ABIN1534191 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for 1534191

  5. Human Polyclonal MED23 Primary Antibody for WB - ABIN152374 : Ablack, Cohen, Thillainadesan, Fonseca, Pelka, Torchia, Mymryk: Cellular GCN5 is a novel regulator of human adenovirus E1A-conserved region 3 transactivation. in Journal of virology 2012 (PubMed)

  6. Cow (Bovine) Polyclonal MED23 Primary Antibody for WB - ABIN2776066 : Kob, Baniahmad, Escher, von Eggeling, Melle: Detection and identification of transcription factors as interaction partners of alien in vivo. in Cell cycle (Georgetown, Tex.) 2007 (PubMed)

更多抗MED23的相互作用对抗体

Human Mediator Complex Subunit 23 (MED23) interaction partners

  1. a 7-gene signature was identified which correctly predicted the primary prefibrotic myelofibrosis group with a sensitivity of 100% and a specificity of 89%. The 7 genes included MPO (显示 MPO 抗体), CEACAM8, CRISP3 (显示 CRISP3 抗体), MS4A3 (显示 MS4A3 抗体), CEACAM6, HEMGN, and MMP8 (显示 MMP8 抗体)

  2. Higher l-arginine (显示 GATM 抗体) was associated with higher risk of Ischemic heart disease (odds ratio and of myocardial infarction, based on 2 SNPs from MED23.

  3. MED23-associated intellectual disability has been found in two brothers from a non-consanguineous family.

  4. MED23 plays an important role in hepatocarcinogenesis, and it may be a novel target for HCC (显示 FAM126A 抗体) therapy.

  5. Upregulation of mediator MED23 in non-small-cell lung cancer promotes the growth, migration, and metastasis of cancer cells.

  6. Mediator MED23 regulates basal transcription in vivo via an interaction with P-TEFb (显示 CCNT1 抗体).

  7. Data show that Med23 RNAi specifically inhibits the proliferation and tumorigenicity of lung cancer cells with hyperactive Ras activity.

  8. missense mutation (p. R617Q) in MED23 that cosegregates with nonsyndromic autosomal recessive intellectual disability; mutation impaired response of JUN and FOS to mitogens by altering interaction between enhancer-bound transcription factors and Mediator

  9. DRIP130 regulates HER2 (显示 ERBB2 抗体) expression by binding to ESX (显示 ELF3 抗体)

  10. loss of DRIP-130 expression, as a result of the gross loss of human chromosome 6q16.3-q23, provokes increased tumor metastasis

Mouse (Murine) Mediator Complex Subunit 23 (MED23) interaction partners

  1. MED23 constitutes a molecular node in the regulatory network of anabolic bone formation and related diseases.

  2. Med23 contributes to controlling T-cell activation at the transcriptional level and prevents the development of autoimmunity.

  3. The hepatic Med23 deletion impaired the Mediator and RNAPII recruitment and attenuated the expression of FOXO1 (显示 FOXO1 抗体) target genes.

  4. Data show that Kruppel-like transcription factors KLF2 (显示 KLF2 抗体) expression is decreased in mediator complex Med23 null thymocytes.

  5. Mediator Med23 deficiency enhances neural differentiation of murine embryonic stem cells through modulating BMP signaling.

  6. Reduced expression of MED23 inhibits cell apoptosis by downregulation of Bax (显示 BAX 抗体), activated Caspase 3 (显示 CASP3 抗体), activated Caspase 9 (显示 CASP9 抗体) and upregulation of cyclinD1 and Bcl2 (显示 BCL2 抗体).

  7. Data show tha tMed23 deficiency in fibroblasts selectively inhibited the oncogenic transformation induced by Ras.

  8. Mediator MED23 controls the cell fate preference that directs differentiation into smooth muscle cells (SMCs) or adipocytes

  9. MED23 regulates a subset of hnRNP L (显示 HNRNPL 抗体)-targeted alternative splicing (AS) and alternative cleavage and polyadenylation (APA (显示 ENPEP 抗体)) events.

  10. MED23 Mediator controls Egr1 gene and stimulates Pol II initiation at a step subsequent to preinitiation complex assembly

Caenorhabditis elegans (C. elegans) Mediator Complex Subunit 23 (MED23) interaction partners

  1. Study shows that sur-2 mutation affects the Cbr (显示 CNR1 抗体)-sur-2/MED23 gene that is orthologous to a C. elegans gene critical for the normal response to the EGF (显示 EGF 抗体) signal. whereas Cel-sur-2 mutants exhibit a reduced vulval development because of defects in the VPC immediately adjacent to the anchor cell (the P6.p cell), similar defects in Caenorhabditis briggsae -sur-2 mutants do not have the same impact.

MED23 抗原简介

Antigen Summary

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with MED23

  • Mediator complex subunit 23 (MED23) 抗体
  • mediator complex subunit 23 (MED23) 抗体
  • mediator complex subunit 23 (LOC100342894) 抗体
  • mediator complex subunit 23 (med23) 抗体
  • mediator of RNA polymerase II transcription subunit 23 (MED23) 抗体
  • mediator complex subunit 23 (Med23) 抗体
  • Protein SUR-2 (sur-2) 抗体
  • 130kDa 抗体
  • 3000002A17Rik 抗体
  • ARC130 抗体
  • CG3695 抗体
  • crsp3 抗体
  • CRSP130 抗体
  • CRSP133 抗体
  • Dmel\\CG3695 抗体
  • DRIP130 抗体
  • dSUR2 抗体
  • dTRAP150beta 抗体
  • ESTM7 抗体
  • Gal11/SUR2 抗体
  • MED23 抗体
  • mKIAA1216 抗体
  • MRT18 抗体
  • si:ch211-272f15.2 抗体
  • SUR-2 抗体
  • Sur2 抗体
  • Trap150 抗体
  • Trap150beta 抗体
  • X83317 抗体
  • zgc:91979 抗体

Protein level used designations for MED23

CG3695-PA , CG3695-PB , MED23-PA , MED23-PB , mediator complex subunit 23 , mediator complex subunit n23 , cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa , Sp1 transcriptional activation cofactor subunit 3 , mediator of RNA polymerase II transcription subunit 23-like , mediator of RNA polymerase II transcription subunit 23 , 130 kDa transcriptional co-activator , 133 kDa transcriptional co-activator , activator-recruited cofactor 130 kDa component , cofactor required for Sp1 transcriptional activation subunit 3 , vitamin D3 receptor interacting protein , CRSP complex subunit 3 , cofactor required for Sp1 transcriptional activation, subunit 3 (130kD) , mSur-2 , protein sur-2 homolog , cofactor required for Sp1 transcriptional activation, subunit 3

GENE ID SPECIES
37639 Drosophila melanogaster
426927 Gallus gallus
472124 Pan troglodytes
474822 Canis lupus familiaris
100067556 Equus caballus
100342894 Oryctolagus cuniculus
100409950 Callithrix jacchus
100433008 Pongo abelii
100545205 Meleagris gallopavo
100562268 Anolis carolinensis
100602785 Nomascus leucogenys
412332 Apis mellifera
100466100 Ailuropoda melanoleuca
9439 Homo sapiens
70208 Mus musculus
309565 Rattus norvegicus
445483 Danio rerio
399060 Xenopus laevis
513610 Bos taurus
173345 Caenorhabditis elegans
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