anti-CADM1 (CADM1) 抗体产品概述

Full name:
anti-Cell Adhesion Molecule 1 抗体 (CADM1)
在www.antibodies-online.cn可供116 Cell Adhesion Molecule 1 (CADM1) 抗体的25不同的供货商。 再加上,我们可以发CADM1 蛋白 (15)CADM1 试剂盒 (8)和数多这个蛋白质的别的产品。 总共150 CADM1产品已列进来了。
别名:
2900073G06Rik, 3100001I08Rik, AI987920, Bl2, Igsf4, Igsf4a, Necl-2, Necl2, RA175, RA175A, RA175B, RA175C, RA175N, SgIGSF, ST17, sTSLC-1, SynCam, synCAM1, Tslc1, xnecl2
列出全部抗体 基因 基因ID UniProt
CADM1 445438  
CADM1 23705 Q9BY67
CADM1 54725 Q8R5M8

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引用最多的anti-CADM1 抗体

  1. Human Polyclonal CADM1 Primary Antibody for EIA, IHC (p) - ABIN951001 : McGovern, Jones, Taylor, Marciante, Yan, Dubinsky, Ippoliti, Vasiliauskas, Berel, Derkowski, Dutridge, Fleshner, Shih, Melmed, Mengesha, King, Pressman, Haritunians, Guo, Targan, Rotter: Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. in Human molecular genetics 2010 (PubMed)
    Show all 5 references for 951001

  2. Human Polyclonal CADM1 Primary Antibody for IF (p), IHC (p) - ABIN738351 : Liu, Cui, Ao, Zhou, Zhou, Yuan, Xiang, Liu, Cao et al.: Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ... in Toxicology and applied pharmacology 2011 (PubMed)
    Show all 2 references for 738351

  3. Human Polyclonal CADM1 Primary Antibody for ICC, IF - ABIN152528 : Biederer, Sara, Mozhayeva, Atasoy, Liu, Kavalali, Südhof: SynCAM, a synaptic adhesion molecule that drives synapse assembly. in Science (New York, N.Y.) 2002 (PubMed)
    Show all 2 references for 152528

  4. Human Polyclonal CADM1 Primary Antibody for IHC, ELISA - ABIN1585332 : Ballester, Gonin, Rodenas, Bernaudin, Rouzier, Coutant, Daraï: Eutopic endometrium and peritoneal, ovarian and colorectal endometriotic tissues express a different profile of nectin-1, -3, -4 and nectin-like molecule 2. in Human reproduction (Oxford, England) 2012 (PubMed)

  5. Human Polyclonal CADM1 Primary Antibody for IHC (p), WB - ABIN654660 : Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010 (PubMed)

更多抗CADM1的相互作用对抗体

Human Cell Adhesion Molecule 1 (CADM1) interaction partners

  1. We conclude that CADM1 was not associated with cell-cell interaction between lymphoma cells and macrophages, although CADM1 may be a useful marker of ATLL for diagnostic procedures.

  2. miR (显示 MLXIP 抗体)-21 overexpression promotes cardiac fibrosis via STAT3 (显示 STAT3 抗体) signaling pathway by decrease CADM1 expression, indicating miR (显示 MLXIP 抗体)-21 as an important signaling molecule for cardiac fibrotic remodeling and atrial fibrillation.

  3. Pathway analysis of the genes associated with the 46 CpG sites revealed an enrichment of immune system process genes, including LYST (显示 LYST 抗体) (cg16962115, FDR = 1.24E-04), CADM1 (cg21933078, FDR = 1.22E-02) and NFATC1 (显示 NFATC1 抗体) (cg06784563, FDR = 1.46E-02)

  4. CADM1 mRNA expression was highly upregulated in normal tissues compared to esophageal squamous cell carcinoma tissues, indicating that the loss of CADM1 expression influenced the pathogenesis, invasion, and metastasis of ESCC.

  5. Eight and five of the nine samples were negative for cell adhesion molecule 1 and Osterix (显示 SP7 抗体) respectively. The other markers showed no statistical significance(CD151 (显示 CD151 抗体),ALP (显示 ALP 抗体)). osteoblastic differentiation can occur in carcinoma cells and that cell adhesion molecule 1 could be a useful marker for identifying this phenomenon in carcinoma tissues

  6. Our results suggest that, as in the CNS, CADM1 interactions drive exocytic site assembly and promote actin network formation. These results support the broader hypothesis that the effects of cell-cell contact on beta-cell maturation and function are mediated by the same extracellular protein interactions that drive the formation of the presynaptic exocytic machinery. These interactions may be therapeutic targets for re...

  7. High expression of CADM1 on most HTLV-1-infected cells in the face of enhanced cytotoxic T lymphocyte counterselection implies that CADM1 confers a strong benefit on the virus.

  8. Decreased expression of TSLC1 is associated with the differentiation in ovarian epithelial cancer. TSLC1 might be used as a molecular marker of severity in early stage ovarian cancer, and to help differentiating benign and malignant ovarian tumors.

  9. Suppression of tumorigenesis by CADM1 may be mediated by the Rb-E2F1 (显示 E2F1 抗体) pathway.

  10. CADM1 prevents squamous cell carcinoma progression by reducing STAT3 (显示 STAT3 抗体) activity

Mouse (Murine) Cell Adhesion Molecule 1 (CADM1) interaction partners

  1. The results of this study demonstrate that the synapse-organizing adhesion molecule (显示 NCAM1 抗体) SynCAM 1 has pronounced effects on neuronal connectivity in the hippocampal CA3 (显示 CA3 抗体) area.

  2. Cadm1 is a direct target of NFATc1 (显示 NFATC1 抗体), which is induced by RANKL (显示 TNFSF11 抗体) through epigenetic modification, and regulates osteoclastic bone resorption in a negative feedback manner.

  3. Data show that cell adhesion molecule 1 (SynCAM 1) generally prolongs the lifetime of spines.

  4. This experiments show that the survival rate of adult-generated neurons is increased by overexpressing SynCAM 1

  5. Our study reveals a novel mechanism of chronic NF-kappaB (显示 NFKB1 抗体) activation by CADM1 in HTLV-1 infected cells

  6. Study demonstrates that polysialic acid-SynCAM 1 defines a subpopulation of NG2 (显示 Vcan 抗体) cells and identifies the presence of polysialic acid-NRP2 (显示 NRP2 抗体) in microglia

  7. CADM1 appeared to sustain gap junctional intercellular communication among alpha-cells via homophilic binding and, based on this action, CADM1 appears to prevent excessive secretion of glucagon (显示 GCG 抗体) from alpha-cells.

  8. This study demonistrated that SynCAM 1 in the synaptic organization of the rod visual pathway and provide evidence for novel roles of synaptic adhesion in the structural and functional integrity of ribbon synapses.

  9. Necl-2 co-localizes with ErbB4 (显示 ERBB4 抗体) in hippocampus and and regulates ErbB4 (显示 ERBB4 抗体) signaling in cultured neurons.

  10. TGF-beta1 is a potent cytokine that provides an effective mechanism in controlling Necl-2 expression in the testis via Smad-dependent gene repression and clathrin-mediated endocytosis.

CADM1 抗原简介

Antigen Summary

Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.

Alternative names and synonyms associated with CADM1

  • cell adhesion molecule 1 (CADM1) 抗体
  • cell adhesion molecule 1 (LOC100354915) 抗体
  • immunoglobulin superfamily, member 4 (IGSF4) 抗体
  • cell adhesion molecule 1 (cadm1) 抗体
  • cell adhesion molecule 1 (Cadm1) 抗体
  • 2900073G06Rik 抗体
  • 3100001I08Rik 抗体
  • AI987920 抗体
  • Bl2 抗体
  • Igsf4 抗体
  • Igsf4a 抗体
  • Necl-2 抗体
  • Necl2 抗体
  • RA175 抗体
  • RA175A 抗体
  • RA175B 抗体
  • RA175C 抗体
  • RA175N 抗体
  • SgIGSF 抗体
  • ST17 抗体
  • sTSLC-1 抗体
  • SynCam 抗体
  • synCAM1 抗体
  • Tslc1 抗体
  • xnecl2 抗体

Protein level used designations for CADM1

immunoglobulin superfamily, member 4 , cell adhesion molecule 1 , TSLC-1 , TSLC1/Nectin-like 2/IGSF4 , immunoglobulin superfamily member 4 , immunoglobulin superfamily, member 4D variant 1 , immunoglobulin superfamily, member 4D variant 2 , nectin-like 2 , nectin-like protein 2 , spermatogenic immunoglobulin superfamily , synaptic cell adhesion molecule , truncated CADM1 protein , tumor suppressor in lung cancer 1 , NECL-2 , cell adhesion molecule 1 transcript variant 8abc , immunoglobulin superfamily member 4A , immunosuperfamily protein Bl2 , immunoglobulin superfamily, member 4A , secretory isoform of TSLC1

GENE ID SPECIES
529873 Bos taurus
100354915 Oryctolagus cuniculus
445438 Rattus norvegicus
735231 Xenopus laevis
23705 Homo sapiens
54725 Mus musculus
363058 Rattus norvegicus
479432 Canis lupus familiaris
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