anti-DCC (DCC) 抗体产品概述

Full name:
anti-Deleted in Colorectal Carcinoma 抗体 (DCC)
在www.antibodies-online.cn可供91 Deleted in Colorectal Carcinoma (DCC) 抗体的23不同的供货商。 再加上,我们可以发DCC 蛋白 (8)DCC 试剂盒 (3)和数多这个蛋白质的别的产品。 总共108 DCC产品已列进来了。
别名:
Abcc1b, C030036D22Rik, CRC18, CRCR1, DCC, dcca-A, dyscalc, Dyscalc1, Igdcc1, MRMV1, Mrp6, xdcc, XDCCa, zdcc

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引用最多的anti-DCC 抗体

  1. Human Monoclonal DCC Primary Antibody for IHC (f), WB - ABIN967443 : Fearon, Cho, Nigro, Kern, Simons, Ruppert, Hamilton, Preisinger, Thomas, Kinzler: Identification of a chromosome 18q gene that is altered in colorectal cancers. in Science (New York, N.Y.) 1990 (PubMed)
    Show all 5 references for 967443

  2. Human Monoclonal DCC Primary Antibody for FACS, WB - ABIN967442 : Fearon, Hamilton, Vogelstein: Clonal analysis of human colorectal tumors. in Science (New York, N.Y.) 1987 (PubMed)
    Show all 5 references for 967442

  3. Mouse (Murine) Polyclonal DCC Primary Antibody for IHC (p), WB - ABIN656268 : Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010 (PubMed)
    Show all 3 references for 656268

  4. Human Polyclonal DCC Primary Antibody for IF, ELISA - ABIN1534435 : Cho, Oliner, Simons, Hedrick, Fearon, Preisinger, Hedge, Silverman, Vogelstein: The DCC gene: structural analysis and mutations in colorectal carcinomas. in Genomics 1994 (PubMed)
    Show all 2 references for 1534435

  5. Human Polyclonal DCC Primary Antibody for EIA, IHC (p) - ABIN953653 : Hanna, Kruskal, Ezekowitz, Bloom, Collier: Role of macrophage oxidative burst in the action of anthrax lethal toxin. in Molecular medicine (Cambridge, Mass.) 1996 (PubMed)
    Show all 2 references for 953653

更多抗DCC的相互作用对抗体

Mouse (Murine) Deleted in Colorectal Carcinoma (DCC) interaction partners

  1. Results suggest that Netrin1/DCC signaling induce neuronal migration in the dorsal spinal cord.

  2. Results suggest that Dcc plays an important role in the developmental formation of peripheral and central auditory circuits, and its mutation may contribute to sensorineural hearing loss.

  3. dcc haploinsufficient mice acquire intracranial self-stimulation behavior and that the parameters of the stimulation are comparable to those observed in wild-type littermates; reduced expression of dcc may dampen the abuse potential of cocaine

  4. Identified the Dcc gene as a novel downstream target of spontaneous calcium activity involved in axon growth.

  5. bisphosphonates may be helpful for prevention of mineral deposits in Pseudoxanthoma elasticum and generalized arterial calcification of infancy caused by mutations in the ABCC6 (显示 ABCC6 抗体) gene.

  6. suggest that DCC signaling functions through NCK1 (显示 NCK1 抗体) and NCK2 (显示 NCK2 抗体) and that both proteins are necessary for the establishment of normal spinal circuits necessary for gait

  7. Results suggest that down syndrome cell adhesion molecule (显示 DSCAM 抗体) collaborates with deleted in colorectal cancer to regulate microtubule dynamics via direct binding to dynamic TUBB3 (显示 TUBB3 抗体) in Netrin-1 (显示 NTN1 抗体)-induced axon branching.

  8. In a mouse model of CKD, ABCC6 (显示 ABCC6 抗体) protein expression was decreased in liver and kidney, however mRNA levels were unchanged.

  9. Data indicate the roles of Slit1 (显示 SLIT1 抗体)/Robo1 (显示 ROBO1 抗体) and Netrin1/DCC signals in positioning motor neuron cell bodies.

  10. These data demonstrate robust cardioprotective effect of netrin-1 (显示 NTN1 抗体) in vivo, as shown by reduced infarct size and improved cardiac function mediated by netrin-1 (显示 NTN1 抗体) receptor DCC.

Zebrafish Deleted in Colorectal Carcinoma (DCC) interaction partners

  1. Schwann cell and dcc-mediated guidance are critical early during regeneration to direct growth cones across the transection gap and onto their original axonal trajectory.

  2. in dcc mutants, turns on the inappropriate side of the body are caused by aberrant ipsilateral axonal projections

  3. Dcc-Netrin1 and roundabout2 (Robo2)-Slit coordinate axonal projection choices of neurons in the developing forebrain.

  4. Dcc regulates polarized axon initiation and asymmetric outgrowth of forebrain neurons

  5. dcc may play roles not only in axon guidance, but in morphogenesis and functioning of these organs as well

  6. First evidence that Netrin/DCC axon guidance molecules act in dendrites in a vertebrate system.

Xenopus laevis Deleted in Colorectal Carcinoma (DCC) interaction partners

  1. ESCRT-II (显示 VPS28 抗体)-mediated endocytic pathway regulates both DCC and local protein synthesis.

Human Deleted in Colorectal Carcinoma (DCC) interaction partners

  1. Environmental and endogenous proteases may contribute to cancer development by depleting DCC and neogenin (显示 NEO1 抗体).

  2. Identified DCC mutations in four families.

  3. DCC polymorphism maybe responsible for successful treatment of patients with hydrochlorothiazide . diagnosed with hypertension.

  4. Deleted in colorectal cancer (DCC) confers susceptibility to depression-like behaviors in humans and mice and Is regulated by miR (显示 MLXIP 抗体)-218. By regulating DCC, miR (显示 MLXIP 抗体)-218 may be a switch of susceptibility versus resilience to stress-related disorders.

  5. DCC/18q and ERBB2 (显示 ERBB2 抗体)/17q gene copy number variations are associated with disease-free survival in microsatellite stable colon cancer

  6. Allelic and genotypic frequencies of the DCC polymorphism rs2229080 were nominally associated with schizophrenia.

  7. Results of APC and DCC LOH, KRAS and microsatellite instability indicate our colorectal cancer cases were typical of sporadic cancers following the 'chromosomal instability' pathway.

  8. The study identified DCC as a differentially expressed gene and clustered meningiomas into DCC low expression (3 grade I and 3 grade II tumors), DCC medium expression (2 grade I and 1 grade II tumors), and DCC high expression (5 grade I tumors) groups.

  9. Data suggest that, in response to netrin-1 (显示 NTN1 抗体)/netrin receptor (DCC) signaling, p120RasGAP (显示 RASA1 抗体) is recruited to growth cones and supports axon outgrowth; p120RasGAP (显示 RASA1 抗体) Src (显示 SRC 抗体) homology 2 domains exhibit scaffolding properties sufficient to support axon outgrowth.

  10. By analyzing multiple myeloma-derived cell lines and patient-derived primary CD138 (显示 SDC1 抗体)-positive plasma cells ... authors show for the first time that transcriptional dysregulation of DCC is involved in the progression of plasma cell malignancy.

DCC 抗原简介

Antigen Summary

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.

Alternative names and synonyms associated with DCC

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (Abcc6) 抗体
  • deleted in colorectal carcinoma (DCC) 抗体
  • deleted in colorectal carcinoma (dcc) 抗体
  • deleted in colorectal carcinoma (Dcc) 抗体
  • Abcc1b 抗体
  • C030036D22Rik 抗体
  • CRC18 抗体
  • CRCR1 抗体
  • DCC 抗体
  • dcca-A 抗体
  • dyscalc 抗体
  • Dyscalc1 抗体
  • Igdcc1 抗体
  • MRMV1 抗体
  • Mrp6 抗体
  • xdcc 抗体
  • XDCCa 抗体
  • zdcc 抗体

Protein level used designations for DCC

ATP-binding cassette sub-family C member 6 , ATP-binding cassette, sub-family C, member 6 , multidrug resistance-associated protein 6 , multidrug resistance-associated protein-6 , deleted in colorectal carcinoma , netrin receptor DCC , deleted in colorectal cancer , deleted in colorectal cancer tumor suppressor , netrin receptor DCC-like , colorectal cancer suppressor , colorectal tumor suppressor , deleted in colorectal cancer protein , immunoglobulin superfamily DCC subclass member 1 , immunoglobulin superfamily, DCC subclass, member 1 , tumor suppressor protein DCC

GENE ID SPECIES
27421 Mus musculus
455425 Pan troglodytes
483976 Canis lupus familiaris
537176 Bos taurus
569360 Danio rerio
693352 Macaca mulatta
100054013 Equus caballus
378529 Xenopus laevis
100442362 Pongo abelii
100410745 Callithrix jacchus
100556072 Anolis carolinensis
100583619 Nomascus leucogenys
1630 Homo sapiens
13176 Mus musculus
25311 Rattus norvegicus
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