HAX1 (HAX1) ELISA试剂盒产品概述

Full name:
HCLS1 Associated Protein X-1 ELISA试剂盒 (HAX1)
在www.antibodies-online.cn可供4 HCLS1 Associated Protein X-1 (HAX1) ELISA试剂盒的1不同的供货商。 再加上,我们可以发HAX1 抗体 (151)HAX1 蛋白 (12)和数多这个蛋白质的别的产品。 总共173 HAX1产品已列进来了。
别名:
HAX-1, hax1, HCLSBP1, Hs1bp1, HSP1BP-1, mHAX-1s, SCN3, SIG-111, Silg111

适于 HAX1 相互作用对的更多 ELISA 试剂盒

Human HCLS1 Associated Protein X-1 (HAX1) interaction partners

  1. results suggest that miR (显示 MLXIP ELISA试剂盒)-223 increases the sensitivity of TNBCSCs to TRAIL-induced apoptosis by targeting HAX-1

  2. The authors describe the first case series of patients with CN caused by HAX1 mutation who presented with HLH. They hypothesize that severe neutropenia persists after an HLH episode in children without FHLH mutations (especially infants) because these patients have CN caused by HAX1 mutations.

  3. Study indicates that the overexpression of HAX-1 is essential in the development of chemoresistance in breast cancer.

  4. Kv3.3 regulates Arp2/3-dependent cortical actin nucleation mediated by Hax-1; resulting cortical actin structures interact with the channel's gating machinery to slow its inactivation rate during sustained membrane depolarizations; a mutation that leads to late-onset spinocerebellar ataxia type 13.

  5. Results show that mRNA and protein levels of HAX-1 in prostate cancer cell lines were significantly higher and inhibits cell apoptosis through caspase-9 (显示 CASP9 ELISA试剂盒) inactivation.

  6. HAX-1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation.

  7. HAX1 knockdown significantly decreased the proliferation. In addition, the expression levels of ki67 (显示 MKI67 ELISA试剂盒) and phosphorylatedakt were inhibited following HAX1 knockdown.

  8. HAX-1 was significantly elevated in laryngeal carcinoma.

  9. Authors showed that HAX1 promotes auto-ubiquitination and degradation of cIAPs by facilitating the intermolecular homodimerization of RING finger (显示 PCGF1 ELISA试剂盒) domain.

  10. HAX-1 is involved in mRNA processing as an element of P-body interaction network.

Mouse (Murine) HCLS1 Associated Protein X-1 (HAX1) interaction partners

  1. HAX1 plays a general role in B cell receptor-mediated internalization events and BCR (显示 BCR ELISA试剂盒)-mediated apoptosis.

  2. The hydrophilic sequences within loop 2, and the matrix-localized hydrophilic domain of UCP3 (显示 UCP3 ELISA试剂盒), were necessary for binding to Hax-1 at the C-terminal domain, adjacent to the mitochondrial inner membrane.

  3. Protease Omi (显示 HTRA2 ELISA试剂盒) impairs mitochondrial function by cleaving Hax-1, which induces apoptosis in oxygen-glucose deprivation and reoxygenation -treated N2a cells and causes reperfusion injury in middle cerebral artery occlusion mice.

  4. Knockdown of HAX1 and EB2 (显示 MAPRE2 ELISA试剂盒) in skin epidermal cells stabilizes focal adhesions and impairs epidermal migration.

  5. These findings reveal the role of HAX-1 in regulating cyclophilin-D (显示 PPIF ELISA试剂盒) levels via an Hsp90 (显示 HSP90 ELISA试剂盒)-dependent mechanism, resulting in protection against activation of mPTP (显示 PTPN2 ELISA试剂盒) and subsequent cell death responses.

  6. anti-apoptotic role of HAX-1 versus BCL-XL (显示 BCL2L1 ELISA试剂盒) in cytokine-dependent bone marrow-derived cells

  7. The expression of Hax-1 in normal brain tissue and reduction of Hax-1 in ischemic brain tissue indicate its possible involvement in pathophysiological functions in the brain.

  8. Cardiac ischemia-reperfusion injury is associated with decreases in HAX-1 levels. Overexpression of HAX-1 promotes cardiomyocyte survival, via its interaction with Hsp90 (显示 HSP90 ELISA试剂盒) and specific inhibition of IRE-1 (显示 ERN1 ELISA试剂盒) signaling at the ER/sarcoplasmic reticulum.

  9. Focal cerebral ischemia significantly decreased cytosolic accumulation of HAX-1, induced an upregulation of HtrA2 (显示 HTRA2 ELISA试剂盒), an upregulation of AIF (显示 AIFM1 ELISA试剂盒) and activation of caspase-3 (显示 CASP3 ELISA试剂盒)

  10. HAX1 deficiency: impact on lymphopoiesis and B-cell development.

HAX1 抗原简介

Antigen Summary

The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with HAX1

  • HCLS1 associated protein X-1 (HAX1) Elisa Kit
  • HCLS1-associated protein X-1 (hax1) Elisa Kit
  • zgc:92196 (zgc:92196) Elisa Kit
  • HCLS1 associated protein X-1 (LOC100348155) Elisa Kit
  • HCLS1 associated protein X-1 (Hax1) Elisa Kit
  • HCLS1 associated X-1 (Hax1) Elisa Kit
  • HAX-1 Elisa Kit
  • hax1 Elisa Kit
  • HCLSBP1 Elisa Kit
  • Hs1bp1 Elisa Kit
  • HSP1BP-1 Elisa Kit
  • mHAX-1s Elisa Kit
  • SCN3 Elisa Kit
  • SIG-111 Elisa Kit
  • Silg111 Elisa Kit

Protein level used designations for HAX1

HCLS1 associated protein X-1 , HCLS1-associated protein X-1 , HAX-1 , HCLS1 (and PKD2) associated protein , HS1 binding protein , HS1-associating protein X-1 , HS1-binding protein 1 , HSP1BP-1 , HS1-associated protein X-1

GENE ID SPECIES
457347 Pan troglodytes
100194877 Salmo salar
436609 Danio rerio
100348155 Oryctolagus cuniculus
10456 Homo sapiens
480134 Canis lupus familiaris
506895 Bos taurus
291202 Rattus norvegicus
23897 Mus musculus
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