SPINK4 Protein (AA 27-86) (His tag)
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- 抗原 See all SPINK4 蛋白
- SPINK4 (Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4))
- 蛋白类型
- Recombinant
- 产品特性
- AA 27-86
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宿主
- 人
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资源
- 人细胞
- 标记
- This SPINK4 protein is labelled with His tag.
- 原理
- Recombinant Human Serpin Kazal-4/SPINK4 (C-6His)
- 序列
- GKLPFSRMPI CEHMVESPTC SQMSNLVCGT DGLTYTNECQ LCLARIKTKQ DIQIMKDGKC VDHHHHHH
- 产品特性
- Recombinant Human Serine Protease Inhibitor Kazal-Type 4/SPINK4 produced by transfected human cells is a secreted protein with sequence (Gly27-Cys86) of human SPINK4 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SPINK4 蛋白
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Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4) protein (Fc Tag)
SPINK4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4) (AA 27-86) protein (His tag)Crystallography grade SPINK4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4) (AA 27-86) protein (His tag)Crystallography grade SPINK4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, 2 mM CaCl2, 1 mM DTT, 0.05 % Brij35, 10 % Glycerol, pH 6.0.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- SPINK4 (Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4))
- 别名
- spink4 (SPINK4 产品)
- 别名
- PEC-60 Protein, PEC60 Protein, MPGC60 Protein, serine peptidase inhibitor, Kazal type 4 Protein, SPINK4 Protein, Spink4 Protein
- Sub Type
- Fusionprotein
- 背景
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Serine Protease Inhibitor Kazal-Type 4 (SPINK4) is a secreted protein containing one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine protease inhibitors of the Kazal type (SPINK) are functional and positional candidate genes for celiac disease (CD). SPINK1 plays an important role in protecting the pancreas against excessive trypsinogen activation. It is a potent natural inhibitor of pancreatic trypsin activity. SPINK1 mutations are associated with the development of acute and chronic pancreatitis and have been detected in all forms of chronic pancreatitis. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein contains a typical Kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK9 was identified in human skin. Its expression was strong in palmar epidermis, but not detectable or very low in non palmoplantar skin.
Alternative Names: Serine Protease Inhibitor Kazal-Type 4, Peptide PEC-60 Homolog, SPINK4 - 分子量
- 7.73 kDa
- UniProt
- O60575
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