Use your antibodies-online credentials, if available.
抗Human FOXO1 抗体:
抗Rat (Rattus) FOXO1 抗体:
抗Mouse (Murine) FOXO1 抗体:
Human Polyclonal FOXO1 Primary Antibody for ICC, IF - ABIN250693
Hoekstra, Sefton, Berry, Lu, Hardt, Marsh, Yin, Clardy, Chakravarti, Bulun, Kim: Progestins activate the AKT pathway in leiomyoma cells and promote survival. in The Journal of clinical endocrinology and metabolism 2009
Show all 8 Pubmed References
Human Polyclonal FOXO1 Primary Antibody for IHC - ABIN966149
Zhao, Gan, Pan, Kan, Majeski, Adam, Unterman: Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms. in The Biochemical journal 2004
Show all 4 Pubmed References
Human Polyclonal FOXO1 Primary Antibody for IF, IHC - ABIN362088
Zhan, Wang, Li, Xu, Sun, Xu: Activation of Akt/FoxO signaling pathway contributes to induction of neuroprotection against transient global cerebral ischemia by hypoxic pre-conditioning in adult rats. in Journal of neurochemistry 2010
Show all 3 Pubmed References
Human Polyclonal FOXO1 Primary Antibody for IHC (fro), IF - ABIN4948288
Sajan, Ivey, Lee, Mastorides, Jurczak, Samuels, Shulman, Braun, Leitges, Farese: PKC? haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes. in Molecular endocrinology (Baltimore, Md.) 2014
Show all 3 Pubmed References
Human Polyclonal FOXO1 Primary Antibody for IHC - ABIN966148
Gan, Zheng, Chabot, Unterman, Quirion: Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors. in Journal of neurochemistry 2005
Show all 2 Pubmed References
Human Monoclonal FOXO1 Primary Antibody for ICC, IHC - ABIN969521
Lau, Koty, Nalbantoglu: Differential response of glioma cells to FOXO1-directed therapy. in Cancer research 2009
Show all 2 Pubmed References
Human Polyclonal FOXO1 Primary Antibody for ICC, IF - ABIN4312363
Sahu, Laakso, Ovaska, Mirtti, Lundin, Rannikko, Sankila, Turunen, Lundin, Konsti, Vesterinen, Nordling, Kallioniemi, Hautaniemi, Jänne: Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer. in The EMBO journal 2011
Show all 2 Pubmed References
Cow (Bovine) Polyclonal FOXO1 Primary Antibody for WB - ABIN2780391
Okamoto, Hribal, Lin, Bennett, Ward, Accili: Role of the forkhead protein FoxO1 in beta cell compensation to insulin resistance. in The Journal of clinical investigation 2006
Show all 2 Pubmed References
Human Polyclonal FOXO1 Primary Antibody for IF, IHC - ABIN362738
Smith, Norton, Gorospe, Jiang, Nemoto, Holbrook, Finkel, Kusiak: Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity. in The Journal of cell biology 2005
Show all 6 Pubmed References
Human Polyclonal FOXO1 Primary Antibody for ELISA, WB - ABIN252951
Paik, Kollipara, Chu, Ji, Xiao, Ding, Miao, Tothova, Horner, Carrasco, Jiang, Gilliland, Chin, Wong, Castrillon, DePinho: FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. in Cell 2007
MicroRNA-183-96-182 cluster regulates bovine granulosa cell function by targeting FOXO1 gene.
downregulation of SIRT1 (显示 SIRT1 抗体) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age
FOXO (显示 FOXO3 抗体) is a key regulator of ROS (显示 ROS1 抗体)-induced apoptosis in mammalian cells.
Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (显示 NCAM1 抗体)-1 mRNA.
The results demonstrate pathways through which two different mediators, TNF-alpha (显示 TNF 抗体) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.
These data suggest that high doses of insulin (显示 INS 抗体) downregulate apoA-I (显示 APOA1 抗体) gene expression in HepG2 cells through redistribution of FOXO1/LXRbeta (显示 NR1H2 抗体) complex, FOXA2 (显示 FOXA2 抗体), and LXRalpha (显示 NR1H3 抗体) on hepatic enhancer of apoA-I (显示 APOA1 抗体) gene.
FOXO1 inhibits the self-renewal capacity of gastric cancer cells through interaction with LGR5 (显示 LGR5 抗体).
elevated expression of microRNA-873 facilitates Th17 differentiation by targeting forkhead box O1 (Foxo1) in the pathogenesis of systemic lupus erythematosus
Results provide a mechanistic understanding for the observation that loss of IGF-1R (显示 IGF1R 抗体) expression decreases tamoxifen sensitivity resulting from reduced FoxO1 expression in breast cancer cells.
Low FOXO1 expression is associated with invasive oral cancer.
TLR4 (显示 TLR4 抗体) and C5aR (显示 C5AR1 抗体) crosstalk in dendritic cells induces a core regulatory network of RSK2 (显示 RPS6KA3 抗体), PI3Kbeta, SGK1 (显示 SGK1 抗体), and FOXO (显示 FOXO3 抗体) transcription factors.
The data suggest that pre-B cells are endowed with a protective mechanism that reduces the risk for aberrant recombinations and chromosomal translocations when exposed to DNA damage, involving the ATM (显示 ATM 抗体)-dependent regulation of FOXO1 binding to the Erag enhancer region.
expression of Bim (显示 BCL2L11 抗体) is mediated by FoxO1 and indirectly downregulated by thyroid hormone/thyroid hormone (显示 PTH 抗体) receptor (显示 THRA 抗体), leading to chemotherapy resistance and doxorubicin-promoted metastasis of hepatoma cells.
this study shows that FoxO1 plays an important role in regulating asbestos-induced apoptosis in T cells
increased FOXO1 represents a critical mechanism driving aberrant self-renewal in preleukemic cells expressing the t(8;21)-associated oncogene AML1 (显示 RUNX1 抗体)-ETO (显示 RUNX1T1 抗体).
These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (显示 AKT1 抗体)-mTOR (显示 FRAP1 抗体)-FOXO1 signaling and suppressing the activation of TLR4 (显示 TLR4 抗体) and/or NOD2 (显示 NOD2 抗体) signaling pathways.
let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (显示 MAP3K1 抗体) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.
inhibition of FoxO1 expression level caused by miR (显示 MYLIP 抗体)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (显示 MYLIP 抗体)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1
Results show that FoxO1 likely regulates MyHC I (显示 MYH7 抗体) negatively and MyHC IIx and MyHC IIb (显示 MYH4 抗体) positively and may play a pivotal role in the determination of muscle fiber type.
Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (显示 TNFSF10 抗体) and Fas ligand FasL (显示 FASL 抗体) expression during follicular atresia.
Data show that IL-4 (显示 IL4 抗体) induces upregulation of the junction protein claudin-5 (显示 CLDN5 抗体) in endothelial cells (ECs) through activation of Jak (显示 JAK3 抗体)/STAT6 (显示 STAT6 抗体) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.
FoxO1 and C/EBPb (显示 CEBPB 抗体) regulate preadipocyte adipogenesis possibly through C/EBPb (显示 CEBPB 抗体)-> FoxO1-> C/EBPb (显示 CEBPB 抗体) feedback regulatory loop and FoxO1-C/EBPb (显示 CEBPB 抗体) protein complex.
FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.
concluded that PI 3 (显示 PI3 抗体)-kinase and Akt (显示 AKT1 抗体) are activated after renal ischemia/reperfusion and that Akt (显示 AKT1 抗体) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (显示 FOXO3 抗体), which may affect epithelial cell fate in acute renal failure.
FoxO1a can regulate p27kip nuclear localization
data reveal apelin (显示 APLN 抗体) as a novel regulator of FoxO1 in cardiac cells and provide evidence for the potential of apelin (显示 APLN 抗体)-13 in prevention of apoptosis and mitochondrial damage in conditions combining I/R injury and obesity.
Besides, both in vivo and in votro studies suggested that K145 stimulated insulin (显示 INS 抗体) dependent Akt (显示 AKT1 抗体) phosphorylation and subsequently activates FoxO1 phosphorylation therefore inhibited gluconeogenetic genes expression including PEPCK (显示 PEPCK 抗体) and G6pase (显示 G6PC 抗体). Our study figures out a potential extent increase the value of developing K145 as therapeutic candidate for diabetes.
Ikaros (显示 IKZF1 抗体) is a transcriptional regulator required for maintaining levels of Foxo1 gene expression in naive T-cells.
this study shows that Foxo1 is a positive regulatory factor for the proliferation and activity of Treg cells
Data show that Fos-Related Antigen-2 (Fra-2 (显示 FOSL2 抗体)) is a key upstream regulator of forkhead box O1 (Foxo1) and interferon regulatory factor 4 (Irf4 (显示 IRF4 抗体)) expression and influences proliferation and differentiation of B cells at multiple stages.
ANG2 (显示 ANGPT2 抗体) activation of Tie2 (显示 TEK 抗体) supports stable enlargement of normal nonleaky vessels, but reduction of Tie1 (显示 TIE1 抗体) in inflammation leads to ANG2 (显示 ANGPT2 抗体) antagonism of Tie2 (显示 TEK 抗体) and initiates a positive feedback loop wherein FOXO1-driven ANG2 (显示 ANGPT2 抗体) expression promotes vascular remodeling and leakage
Link between the antioxidative activity of FoxO1 with PINK1 (显示 PINK1 抗体)/Parkin (显示 PARK2 抗体)-induced mitophagy, indicating a novel role of FoxO1 in diabetic nephropathy.
Pyruvate dehydrogenase kinase 4 (显示 PDK4 抗体) is a direct transcriptional target of FoxO1 in the heart. FoxO1 directly regulates Pdk4 (显示 PDK4 抗体) transcription in the heart, thereby controlling PDH (显示 PDP 抗体) activity and subsequent glucose oxidation rates.
the overlap of IR and IGF1R (显示 IGF1R 抗体) signaling is critical to the regulation of muscle protein turnover, and this regulation depends on suppression of FoxO (显示 FOXO3 抗体)-regulated, autophagy-mediated protein degradation
These results suggest that the LKB1 (显示 STK11 抗体)-AMPK (显示 PRKAA1 抗体)-FoxO1 signaling pathway is a critical mediator of the antioxidant properties of H2, further supporting the idea that H2 acts as a signaling molecule to serve various physiological functions.
FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (显示 SOD1 抗体) and catalase (显示 CAT 抗体) mRNA and protein levels in this organ.
These results indicate that miR (显示 MYLIP 抗体)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.
gas6 (显示 GAS6 抗体) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (显示 AKT1 抗体)-dependent inactivation of FOXO1a.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
forkhead box protein O1
, forkhead box protein O1A
, forkhead, Drosophila, homolog of, in rhabdomyosarcoma
, forkhead box O1A
, forkhead box protein O1-A
, fox family transcription factor FoxO1a.1
, foxhead box protein O1-A
, Forkhead box protein O1A
, Forkhead in rhabdomyosarcoma
, forkhead box O1A (rhabdomyosarcoma)
, forkhead box O1a
, forkhead in rhabdomyosarcoma
, forkhead protein 1
, forkhead/winged helix transcription factor FOXO1a
, forkhead box O1
, forkhead box protein O1-like