P2RX7
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
蛋白结构域
Middle Region
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-P2RX7 antibody (Catalog #: ARP35517_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.