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Matrix Metalloproteinase 20 (MMP20) (Middle Region) Peptide

MMP20 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN980155
发货至: 中国
  • 抗原 See all MMP20 products
    MMP20 (Matrix Metalloproteinase 20 (MMP20))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-MMP20 antibody (Catalog #: ARP46497_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    MMP20 (Matrix Metalloproteinase 20 (MMP20))
    别名
    AI2A2 Peptide, MMP-20 Peptide, MMP25 Peptide, MMP20 Peptide, mmp20 Peptide, matrix metallopeptidase 20 Peptide, matrix metallopeptidase 20 L homeolog Peptide, matrix metallopeptidase 20 (enamelysin) Peptide, MMP20 Peptide, mmp20.L Peptide, Mmp20 Peptide
    背景
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP20 degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. A mutation in the gene encoding MMP20, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes that localizes to chromosome 11q22.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: AI2A2, MMP-20

    Protein Interaction Partner: ACAN

    Protein Size: 483
    分子量
    43 kDa
    基因ID
    9313
    NCBI登录号
    NM_004771, NP_004762
    UniProt
    O60882
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