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G Protein Pathway Suppressor 2 (GPS2) (C-Term) Peptide

GPS2 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5511198
发货至: 中国
  • 抗原 See all GPS2 products
    GPS2 (G Protein Pathway Suppressor 2 (GPS2))
    蛋白结构域
    C-Term
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    TAQPPPHYGP TQPAYSPSQQ LRAPSAFPAV QYLSQPQPQP YAVHGHFQPT
    产品特性
    This is a synthetic peptide designed for use in combination with anti-GPS2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    GPS2 (G Protein Pathway Suppressor 2 (GPS2))
    别名
    gps2 Peptide, MGC68832 Peptide, MGC63588 Peptide, zgc:63588 Peptide, GPS2 Peptide, MGC133909 Peptide, amf-1 Peptide, AMF-1 Peptide, AI505953 Peptide, G protein pathway suppressor 2 Peptide, G protein pathway suppressor 2 L homeolog Peptide, gps2 Peptide, gps2.L Peptide, GPS2 Peptide, Gps2 Peptide
    背景
    This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

    Alias Symbols: GPS2,

    Protein Size: 327
    基因ID
    2874
    NCBI登录号
    XP_005256674
    UniProt
    Q13227
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