RNA Binding Motif Protein 8A (RBM8A) (N-Term) Peptide
RBM8A
适用: 人, 大鼠
宿主: 合成
BP, WB
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- 抗原 See all RBM8A products
- RBM8A (RNA Binding Motif Protein 8A (RBM8A))
- 蛋白结构域
- N-Term
- 宿主
- 人, 大鼠
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- EDFAMDEDGD ESIHKLKEKA KKRKGRGFGS EEGSRARMRE DYDSVEQDGD
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-Rbm8a Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- RBM8A (RNA Binding Motif Protein 8A (RBM8A))
- 别名
- BOV-1A Peptide, BOV-1B Peptide, BOV-1C Peptide, C1DELq21.1 Peptide, DEL1q21.1 Peptide, MDS014 Peptide, RBM8 Peptide, RBM8B Peptide, TAR Peptide, Y14 Peptide, ZNRP Peptide, ZRNP1 Peptide, 2310057C03Rik Peptide, AA673428 Peptide, Rbm8 Peptide, RBM8A Peptide, rbm8 Peptide, rbm8a Peptide, rnp-5 Peptide, fb34f03 Peptide, wu:fb34f03 Peptide, zgc:110525 Peptide, rbm8-A Peptide, rbm8a-A Peptide, rbm8-B Peptide, RNA binding motif protein 8A Peptide, RNA binding motif protein 8a Peptide, RNA binding motif protein 8A S homeolog Peptide, RNA binding motif protein 8A L homeolog Peptide, RBM8A Peptide, Rbm8a Peptide, rbm8a Peptide, rbm8a.S Peptide, rbm8a.L Peptide
- 背景
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Rbm8a is a component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mRNA and thereby influences downstream processes of gene expression including mRNA splicing, nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). The heterodimer MAGOH-RBM8A interacts with PYM that function to enhance the translation of EJC-bearing spliced mRNAs by recruiting them to the ribosomal 48S preinitiation complex.
Alias Symbols: Rbm8
Protein Size: 174 - 分子量
- 19 kDa
- 基因ID
- 295284
- NCBI登录号
- XM_215637, XP_215637
- UniProt
- Q27W01
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