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Mouse (Murine) FSHB ELISA Kit for Sandwich ELISA - ABIN455141
Hejmej, Kotula-Balak, Chojnacka, Kuras, Lydka-Zarzycka, Bilinska: Photoperiod-Dependent Effects of 4-tert-Octylphenol on Adherens and Gap Junction Proteins in Bank Vole Seminiferous Tubules. in International journal of endocrinology 2013
Action of Lh and Fsh (显示 BRD2 ELISA试剂盒) signaling is redundant in that either alone can support zebrafish spermatogenesis.
FSH (显示 BRD2 ELISA试剂盒)-deficient zebrafish (fshb(-/-)) were surprisingly fertile in both sexes; however, the development of both the ovary and testis was significantly delayed.
zfFSHbeta promoter responded to 6h of gonadotropin-releasing hormone treatment by activating calcium influx and protein kinase C (PKC (显示 PKC ELISA试剂盒)), but after 24h, GnRH (显示 GNRH1 ELISA试剂盒) induction was generated by activation of extracellular-regulated kinase 1/2 and repression by PKC (显示 PKC ELISA试剂盒).
LHbeta (显示 LHB ELISA试剂盒) and LH-R (显示 LHCGR ELISA试剂盒) mRNA expression might be involved in initial maturation events of gametes, at least in males, while the gradually increase of FSH-R (显示 FSHR ELISA试剂盒) mRNA coincided with the advancing process of gamete maturation in both sexes
A major regulatory mechanism for FSH (显示 BRD2 ELISA试剂盒) glycosylation involves control of beta-subunit (显示 POLG ELISA试剂盒) N-glycosylation, possibly by inhibition of oligosaccharyl transferase. Two primate species exhibited the same all-or-none pattern of pituitary FSHbeta glycosylation.
These mice showed an increase in FSH (显示 BRD2 ELISA试剂盒) levels, but they remained in a prepubertal state. Together with previous findings, our data indicate that leptin (显示 LEP ELISA试剂盒)-selective action in gonadotropes serves a role in adult reproductive physiology but is not sufficient to allow pubertal maturation in mice.
GnRH (显示 GNRH1 ELISA试剂盒) stimulated the secretion of the VGF (显示 VGF ELISA试剂盒)-derived peptide NERP1 (显示 VGF ELISA试剂盒). NERP1 (显示 VGF ELISA试剂盒) caused a concentration-dependent decrease in Fshb gene induction.
the signaling pathways mediating GnRH activation of CREB and ICER are distinct, contributing to the decoding of the pulsatile GnRH to regulate FSHbeta expression.
Data show that estradiol or bisphenol A decreased expression of luteinizing hormone beta (Lhb (显示 LHB ELISA试剂盒)), follicle stimulating hormone beta (Fshb), and intracellular adhesion molecule (显示 NCAM1 ELISA试剂盒)-5 (Icam5 (显示 ICAM5 ELISA试剂盒)) in females but only decreased expression of Icam5 (显示 ICAM5 ELISA试剂盒) in males.
GnRH (显示 GNRH1 ELISA试剂盒) stimulation of Fshb expression is dependent on miR (显示 MLXIP ELISA试剂盒)-132/212 and involves a SIRT1 (显示 SIRT1 ELISA试剂盒)-FOXO1 (显示 FOXO1 ELISA试剂盒) pathway.
results suggest that FOXO1 (显示 FOXO1 ELISA试剂盒) binding to the proximal Fshb promoter as well as FOXO1 (显示 FOXO1 ELISA试剂盒) interaction with SMAD3 (显示 SMAD3 ELISA试剂盒)/4 proteins may result in decreased activin (显示 Actbeta ELISA试剂盒) induction of Fshb in gonadotropes
SCGB3A2 (显示 SCGB3A2 ELISA试剂盒) regulates FSH (显示 BRD2 ELISA试剂盒)/LH production in the anterior pituitary lobe.
Data suggest that the BMP2 (显示 BMP2 ELISA试剂盒)-like Activin A (显示 INHBA ELISA试剂盒)/BMP2 (显示 BMP2 ELISA试剂盒) chimera AB215 regulates follicle stimulating hormone beta (FSHbeta) induction in LbetaT2 gonadotroph cells due to its ability to block activin A (显示 INHBA ELISA试剂盒) signaling.
Two regions of the proximal Fshb promoter (-50/-41 and -30/-21) appear to be necessary for FOXO1 (显示 FOXO1 ELISA试剂盒) suppression of GnRH (显示 GNRH1 ELISA试剂盒)-induced Fshb transcription.
Data suggest BMP2 (bone morphogenetic protein 2) stimulates SMAD2/3 signaling in gonadotrophs via Bmpr1a (bone morphogenetic protein receptor type 1A); such signaling via SMAD3 appears to be necessary for up-regulation of Fshb transcription.
Genetic variation affecting FSH (显示 BRD2 ELISA试剂盒) production (FSHB c.-211G>T) was associated with age at pubertal onset, as assessed by testicular enlargement. The effect appeared further modified by coexistence of genetic variation affecting FSH (显示 BRD2 ELISA试剂盒) sensitivity (FSHR (显示 FSHR ELISA试剂盒) c.-29G>A).
A novel homozygous mutation in the FSHbeta gene (c.343C > T) identified in a male patient with isolated FSH (显示 BRD2 ELISA试剂盒) deficiency and infertility.
Association of the FSHB 211G > T polymorphism with male infertility in Han-Chinese
Genetic variations of FSH (显示 BRD2 ELISA试剂盒) signaling appear to determine the individual set point of the hypothalamic-pituitary-gonadal axis already early in life.
Modeling and high-throughput experimental data uncover the mechanisms underlying Fshb gene sensitivity to gonadotropin-releasing hormone pulse frequency
Variants in FSHB gene are associated with polycystic ovary syndrome and LH levels in Han Chinese women.
Data indicate that compared with normal eggs, oocytes with a brown zona pellucida (ZP) were found to have a higher ZP thickness (ZPT), lower embryo quality and lower pregnancy rate, which might be due to a high gonadotropin (Gn) dosage injection and high serum follicle stimulating hormone (FSH (显示 BRD2 ELISA试剂盒)) levels.
genetic association studies in peripubertal girls in Denmark: Data suggest that an SNP in FSHR (follicle stimulating hormone receptor (显示 FSHR ELISA试剂盒), c.2039A>G) is associated with blood levels of FSH (显示 BRD2 ELISA试剂盒), LH, and estradiol; minor alleles in FSHB (follicle stimulating hormone beta subunit, c.-211G>T) and FSHR (显示 FSHR ELISA试剂盒) (c.-29G>A) are associated with delayed pubertal onset.
The FSHB -211G>T variant attenuates serum FSH (显示 BRD2 ELISA试剂盒) levels in the supraphysiological gonadotropin setting of Klinefelter syndrome
3 known FSH-action modulating SNPs (FSHB -211G/T; FSHR -29G/A, c.2039 A/G)explained together 2.3%, 1.4%, 1.0 and 1.1% of the measured variance in serum FSH, Inhibin B, testosterone and total testes volume, respectively.
Study describes generation and characterization of a new Fshb-iCre deleter strain using 4.7 kb of ovine Fshb promoter sequences driving iCre expression exclusively in the gonadotrope lineage with mice developing normally, and fertile.
the novel cis (显示 CISH ELISA试剂盒)-regulatory element generated by the c.-1539_-1538delGGinsTTAACT mutations might play an important role in repressing FSHB transcription, possibly leading to reduced fertility
A 200-base region in the bovine FSHbeta 3' untranslated region downregulates reporter expression at the translational level via interactions between AREs in both the 3'UTR (显示 UTS2R ELISA试剂盒) and transfactors.
The shift in FSH (显示 BRD2 ELISA试剂盒) isoforms toward a greater abundance of the less acidic isoforms appears to be a key component in determining the capability for producing a preovulatory rise in estradiol.
The effect of a single nucleotide polymorphism of the follicle stimulating hormone beta chain on bull fertility and semen quality is reported.
As in vitro experiments in the present study suggested that LHX2 (显示 LHX2 ELISA试剂盒) regulated the expression of Fshbeta, it is possible that LHX2 (显示 LHX2 ELISA试剂盒) controls FSH (显示 BRD2 ELISA试剂盒) synthesis at the transcriptional level.
Results showed that the effects of FSHb, ESR (显示 ESR1 ELISA试剂盒), and PRLR (显示 PRLR ELISA试剂盒) genes were significant in the Tibet pig population, and the effective genotypes of the three genes for reproductive traits were BB, BB, and AA, respectively.
LHX3 (显示 LHX3 ELISA试剂盒) LIM homeodomain (显示 LHX2 ELISA试剂盒) transcription factor is involved in activation of the FSH beta-subunit (显示 POLG ELISA试剂盒) gene in the pituitary gonadotrope cell.
Prop-1 (显示 PROP1 ELISA试剂盒) participates in the regulation of FSHbeta gene
A allele of FSHbeta-1 locus in all the population and FSHbeta-2 locus in pigs of the first parity had the positive effective on TNB, NBA, and WB.
The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein.
, Gth I
, follicle-stimulating hormone beta subunit
, follitropin subunit beta
, FSH beta
, follcle-stimulating hormone beta subunit
, follicle stimulating hormone, beta polypeptide
, follitropin beta chain
, Follicle-stimulating hormone beta subunit
, follicle stimulating hormone beta-subunit
, follitropin, beta chain
, follicle - stimulating hormone subunit beta
, follicle stimulating hormone beta
, follicle-stimulating hormone beta-subunit
, follicle-stimulating hormone subunit beta
, class 1 follicle-stimulating hormone beta polypeptide
, class 2 follicle-stimulating hormone beta polypeptide
, follicule stimulating hormone, beta polypeptide
, follicle stimulating hormone beta subunit
, follitropin beta subunit