anti-LFNG (LFNG) 抗体产品概述

在www.antibodies-online.cn可供62 LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) 抗体的14不同的供货商。 再加上,我们可以发LFNG 试剂盒 (15)LFNG 蛋白 (10)和数多这个蛋白质的别的产品。 总共91 LFNG产品已列进来了。
别名:
AW061165, id:ibd2614, id:ibd5029, id:ibd5138, l-fng, SCDO3, wu:fc69h02, wu:fi34c01
列出全部抗体 基因 基因ID UniProt
LFNG 3955 Q8NES3
LFNG 16848 O09010
LFNG 170905 Q924T4

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抗Human LFNG 抗体:

抗Mouse (Murine) LFNG 抗体:

抗Rat (Rattus) LFNG 抗体:

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更多抗LFNG的相互作用对抗体

Human LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) interaction partners

  1. a potent tumor-suppressive function for Lfng

  2. TGFBR2 (显示 TGFBR2 抗体) signaling can affect Notch1 (显示 NOTCH1 抗体) glycosylation via regulation of glycosyltransferase (显示 GTDC2 抗体) LFNG expression and provide a first mechanistic example for altered glycosylation in microsatellite instability colorectal tumor cells.

  3. LFNG expression correlates with expansion of cancer stem cell populations and NKX3.1 (显示 NKX3-1 抗体) expression in human prostate cancer.

  4. Reduced LFNG expression facilitates JAG/NOTCH (显示 NOTCH1 抗体) luminal progenitor signaling and cooperates with MET/CAVEOLIN basal-type signaling to promote basal-like breast cancer.

  5. Mutation of the LFNG gene causes spondylocostal dysostosis with a severe vertebral phenotype, reinforcing the hypothesis that proper regulation of the Notch (显示 NOTCH1 抗体) signaling pathway is an absolute requirement for the correct patterning of the axial skeleton.

Mouse (Murine) LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) interaction partners

  1. a potent tumor-suppressive function for Lfng

  2. Fringe modifications at EGF8 and EGF12 enhanced Notch1 binding to and activation from Delta-like 1, while modifications at EGF6 and EGF36 (added by Manic and Lunatic but not Radical) inhibited Notch1 activation from Jagged1.

  3. LFNG protein may have context-dependent effects on Notch (显示 NOTCH1 抗体) activity; somitogenesis is disrupted by a novel dominant allele of Lfng

  4. Lfng expression and activity is normal in mice whose Lfng is lengthened by 10 kb, and no effects on segmentation are evident.

  5. suggest that modulation of the Notch (显示 NOTCH1 抗体) signaling by Lfng affects the clock period during development

  6. STAT5 (显示 STAT5A 抗体)-dependent amplification of Notch (显示 NOTCH1 抗体)-modifying Lfng augments Th2 response via Dll4 (显示 DLL4 抗体) and is critical for amplifying viral exacerbation during allergic airway disease.

  7. The repressive effect of Lfng against Notch (显示 NOTCH1 抗体) activities in neighbouring cells can sufficiently explain the synchronization in vivo.

  8. Intriguing changes are observed in the cranio-caudal (显示 CAD 抗体) borders of multifidus muscle in mutant Dll3 (显示 DLL3 抗体) and Lfng models of idiopathic scoliosis.

  9. Reduced LFNG expression facilitates JAG/NOTCH (显示 NOTCH1 抗体) luminal progenitor signaling and cooperates with MET/CAVEOLIN basal-type signaling to promote basal-like breast cancer.

  10. the presence of Gal (显示 GAL 抗体) on O-fucose glycans differentially affects DLL1 (显示 DLL1 抗体)-induced NOTCH (显示 NOTCH1 抗体) signaling modulated by LFNG versus MFNG (显示 MFNG 抗体)

Zebrafish LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) interaction partners

  1. lfng regulates delta-notch (显示 NOTCH1 抗体) induction of hypochord.

  2. The sequence and embryonic expression of lfng were studied.

  3. Lfng acts in a feedback loop downstream of proneural genes.

LFNG 抗原简介

Antigen Summary

This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with LFNG

  • LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (LFNG) 抗体
  • lunatic fringe (LOC100218383) 抗体
  • LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (Lfng) 抗体
  • lunatic fringe (lfng) 抗体
  • lunatic fringe homolog (lfng) 抗体
  • AW061165 抗体
  • id:ibd2614 抗体
  • id:ibd5029 抗体
  • id:ibd5138 抗体
  • l-fng 抗体
  • SCDO3 抗体
  • wu:fc69h02 抗体
  • wu:fi34c01 抗体

Protein level used designations for LFNG

lunatic fringe , beta-1,3-N-acetylglucosaminyltransferase lunatic fringe , O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase , lunatic fringe gene homolog , lunatic fringe homolog

GENE ID SPECIES
100012518 Monodelphis domestica
100218383 Taeniopygia guttata
3955 Homo sapiens
516209 Bos taurus
16848 Mus musculus
170905 Rattus norvegicus
395790 Gallus gallus
101112372 Ovis aries
397855 Xenopus laevis
30158 Danio rerio
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