JAG1 (JAG1) ELISA试剂盒产品概述

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Jagged 1 ELISA试剂盒 (JAG1)
在www.antibodies-online.cn可供19 Jagged 1 (JAG1) ELISA试剂盒的9不同的供货商。 再加上,我们可以发JAG1 抗体 (183)JAG1 蛋白 (27)和数多这个蛋白质的别的产品。 总共239 JAG1产品已列进来了。
别名:
ABE2, AGS, AHD, AWS, CD339, Gsfabe2, HJ1, Htu, JAG1, JAGL1, Ozz, Ser-1

JAG1 (JAG1) ELISA试剂盒 by Reactivity

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引用最多的JAG1 ELISA试剂盒

  1. Human JAG1 ELISA Kit for Sandwich ELISA - ABIN417745 : Zeng, Jin, Ao, Cleveland, Song, Xu, Fullerton, Meng: Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves. in Circulation 2012 (PubMed)
    Show all 6 references for 417745

适于 JAG1 相互作用对的更多 ELISA 试剂盒

Human Jagged 1 (JAG1) interaction partners

  1. Results showed that JAG1 was significantly downregulated in miR (显示 MLXIP ELISA试剂盒)-26a-overexpressing osteosarcoma cells and is a direct target of miR (显示 MLXIP ELISA试剂盒)-26a.

  2. the effects of two Notch (显示 NOTCH1 ELISA试剂盒) ligands, i.e., Jagged1 and DLL1 (显示 DLL1 ELISA试剂盒), on murine and human hematopoiesis in vitro. Our observations indicate that the stromal expression of Notch (显示 NOTCH1 ELISA试剂盒) ligands increases the production of both the total and phenotypically early murine and human hematopoietic cells in the co-culture.

  3. Specific Notch3 (显示 NOTCH3 ELISA试剂盒) and Jag1 subcellular localization patterns may provide clues for the behavior of the corresponding tumors and could potentially be applied in the clinic for Jag1 targeting in triple-negative breast cancer patients.

  4. there is a cross-talk between Jagged1/Notch3 (显示 NOTCH3 ELISA试剂盒) and VEGF (显示 VEGFA ELISA试剂盒) in TNBC angiogenesis. Jagged1/Notch3 (显示 NOTCH3 ELISA试剂盒) is expected to be an important signaling pathway for TNBC progression and a potential target for TNBC neovascularization therapy.

  5. Low levels of Notch pathway genes Notch1, Notch2, Notch4 and Jagged1 correlated with poor prognostic factors such as larger tumor size, positive lymph-node status, tumor phenotype and infiltrating tumor Treg cells.

  6. Human Jagged-1 induced the proliferation and differentiation of CD133+ cord blood progenitors compared with hDll-1. Thus, hJagged-1 signaling in the bone marrow niche may be used to expand EPCs for therapeutic angiogenesis

  7. By studying leprosy as a model, we provide evidence that upregulation of JAG1 on endothelium instructs monocytes to differentiate into M1 macrophages with antimicrobial activity.

  8. High Jag1 expression is associated with metastasis in colorectal cancer.

  9. amplification of Jagged1 contributed to mRNA expression that activates the Jagged1-Notch (显示 NOTCH1 ELISA试剂盒) signaling pathway in liver cancer and led to poor outcome.

  10. Our data revealed that MALAT1 inhibited tongue cancer cell growth and metastasis through miR-124-dependent JAG1 regulation. In conclusion, we revealed that MALAT1 may play an oncogenic role by increasing proliferation and metastasis of tongue cancer and is a potential therapeutic target in human tongue cancer.

Mouse (Murine) Jagged 1 (JAG1) interaction partners

  1. the effects of two Notch (显示 NOTCH1 ELISA试剂盒) ligands, i.e., Jagged1 and DLL1 (显示 DLL1 ELISA试剂盒), on murine and human hematopoiesis in vitro. Our observations indicate that the stromal expression of Notch (显示 NOTCH1 ELISA试剂盒) ligands increases the production of both the total and phenotypically early murine and human hematopoietic cells in the co-culture.

  2. Fringe modifications at EGF8 and EGF12 enhanced Notch1 binding to and activation from Delta-like 1, while modifications at EGF6 and EGF36 (added by Manic and Lunatic but not Radical) inhibited Notch1 activation from Jagged1.

  3. A Jagged1-Hey1 (显示 HEY1 ELISA试剂盒) signal might mediate the impairment of angiogenesis induced by Ang II (显示 AGT ELISA试剂盒) during cardiac hypertrophy.

  4. Data show that Rac1 induced nuclear import of STAT3 (显示 STAT3 ELISA试剂盒) by physical binding, and nuclear STAT3 (显示 STAT3 ELISA试剂盒) directly activated the transcription of essential oocyte-specific genes, including Jagged1, GDF9 (显示 GDF9 ELISA试剂盒) and BMP15 (显示 BMP15 ELISA试剂盒).

  5. Diabetes mellitus induces Jagged1 overexpression and suppresses Notch signaling in endothelial cells. Blocking Jagged1 prevented diabetes-induced microvasculopathy and could reverse it even after 4 weeks.

  6. Jagged1 intracellular domain-mediated inhibition of Notch1 (显示 NOTCH1 ELISA试剂盒) signalling regulates cardiac homeostasis in the postnatal heart.

  7. endothelial Jagged1 has a role in promoting solid tumor development

  8. Jag1 expression in pulmonary capillary endothelial cells is upregulated after repeated lung injury and contributes to lung fibrosis.

  9. On a C57BL/6 background, Jag1 haploinsufficiency results in bile duct paucity in mice

  10. Jag1-induced Notch (显示 NOTCH1 ELISA试剂盒) activity and the subsequent (or concomitant) downregulation of the Dll4 (显示 DLL4 ELISA试剂盒)-mediated signalling are both required for generating haematopoietic stem cells in the embryo.

JAG1 抗原简介

Antigen Summary

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Alternative names and synonyms associated with JAG1

  • jagged 1 (JAG1) Elisa Kit
  • jagged 1 (jag1) Elisa Kit
  • jagged 1 (Jag1) Elisa Kit
  • ABE2 Elisa Kit
  • AGS Elisa Kit
  • AHD Elisa Kit
  • AWS Elisa Kit
  • CD339 Elisa Kit
  • Gsfabe2 Elisa Kit
  • HJ1 Elisa Kit
  • Htu Elisa Kit
  • JAG1 Elisa Kit
  • JAGL1 Elisa Kit
  • Ozz Elisa Kit
  • Ser-1 Elisa Kit

Protein level used designations for Jagged 1 (JAG1) ELISA试剂盒

jagged 1 (Alagille syndrome) , jagged 1 , protein jagged-1-like , protein jagged-1 , Serrate-1

GENE ID SPECIES
718580 Macaca mulatta
780486 Ovis aries
100474031 Ailuropoda melanoleuca
100486874 Xenopus (Silurana) tropicalis
100547052 Meleagris gallopavo
100566281 Anolis carolinensis
182 Homo sapiens
29146 Rattus norvegicus
16449 Mus musculus
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